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Related papers: Multi-Focus Querying of the Human Genome Informati…

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Biologists are leading current research on genome characterization (sequencing, alignment, transcription), providing a huge quantity of raw data about many genome organisms. Extracting knowledge from this raw data is an important process…

Quantitative Methods · Quantitative Biology 2007-05-23 Nicolas Férey , Pierre-Emmanuel Gros , Joan Hérisson , Rachid Gherbi

Large scale visual understanding is challenging, as it requires a model to handle the widely-spread and imbalanced distribution of <subject, relation, object> triples. In real-world scenarios with large numbers of objects and relations,…

Computer Vision and Pattern Recognition · Computer Science 2019-08-20 Ji Zhang , Yannis Kalantidis , Marcus Rohrbach , Manohar Paluri , Ahmed Elgammal , Mohamed Elhoseiny

We investigate a densely packed, non-random arrangement of forty-six chromosomes (46,XY) in human nuclei. Here, we model systems-level chromosomal crosstalk by unifying intrinsic parameters (chromosomal length and number of genes) across…

Genomics · Quantitative Biology 2017-11-09 Sarosh N. Fatakia , Ishita S. Mehta , Basuthkar J. Rao

The ability to precisely visualize the atomic geometry of the interactions between a drug and its protein target in structural models is critical in predicting the correct modifications in previously identified inhibitors to create more…

Biomolecules · Quantitative Biology 2018-08-14 Erick Martins Ratamero , Dom Bellini , Christopher G. Dowson , Rudolf A. Roemer

Virtual reality (VR) enables data visualization in an immersive and engaging manner, and it can be used for creating ways to explore scientific data. Here, we use VR for visualization of 3D histology data, creating a novel interface for…

Graphics · Computer Science 2022-01-31 Kaisa Liimatainen , Leena Latonen , Masi Valkonen , Kimmo Kartasalo , Pekka Ruusuvuori

It has been shown that genome spatial structures largely affect both genome activity and DNA function. Knowing this, many researchers are currently attempting to accurately model genome structures. Despite these increased efforts there…

Genomics · Quantitative Biology 2015-07-24 Jackson Nowotny , Avery Wells , Lingfei Xu , Renzhi Cao , Tuan Trieu , Chenfeng He , Jianlin Cheng

Each human genome is a 3 billion base pair set of encoding instructions. Decoding the genome using deep learning fundamentally differs from most tasks, as we do not know the full structure of the data and therefore cannot design…

Machine Learning · Computer Science 2016-05-24 Laura Deming , Sasha Targ , Nate Sauder , Diogo Almeida , Chun Jimmie Ye

The effective visualization of genomic data is crucial for exploring and interpreting complex relationships within and across genes and genomes. Despite advances in developing dedicated bioinformatics software, common visualization tools…

Genomics · Quantitative Biology 2024-11-22 Thomas Hackl , Markus Ankenbrand , Bart van Adrichem , David Wilkins , Kristina Haslinger

Realistic human-centric rendering plays a key role in both computer vision and computer graphics. Rapid progress has been made in the algorithm aspect over the years, yet existing human-centric rendering datasets and benchmarks are rather…

Despite progress in perceptual tasks such as image classification, computers still perform poorly on cognitive tasks such as image description and question answering. Cognition is core to tasks that involve not just recognizing, but…

Computer Vision and Pattern Recognition · Computer Science 2016-02-25 Ranjay Krishna , Yuke Zhu , Oliver Groth , Justin Johnson , Kenji Hata , Joshua Kravitz , Stephanie Chen , Yannis Kalantidis , Li-Jia Li , David A. Shamma , Michael S. Bernstein , Fei-Fei Li

Data visualization is a fundamental tool in genomics research, enabling the exploration, interpretation, and communication of complex genomic features. While machine learning models show promise for transforming data into insightful…

An approach for approximately calculating the number of genes in a genome is presented, which takes into account the average protein length expected for the species. A number of virus, bacterial and eukaryotic genomes are scrutinized.…

Genomics · Quantitative Biology 2015-02-13 N. S. Santos-Magalhaes , H. M. de Oliveira

The CellxGene project has enabled access to single-cell data in the scientific community, providing tools for browsed-based no-code analysis of more than 500 annotated datasets. However, single-cell data requires dimensional reduction to…

Human-Computer Interaction · Computer Science 2022-12-02 Luke Hyman , Ivo F. Sbalzarini , Stephen Quake , Ulrik Günther

In recent years, substantial advancements have been achieved in understanding the diversity of the human virome and its intricate roles in human health and diseases. Despite this progress, the field of human virome research remains nascent,…

Quantitative Methods · Quantitative Biology 2024-02-26 Yifan Wu , Yousong Peng

Genomic data visualization is essential for interpretation and hypothesis generation as well as a valuable aid in communicating discoveries. Visual tools bridge the gap between algorithmic approaches and the cognitive skills of…

Genomics · Quantitative Biology 2019-11-04 Sabrina Nusrat , Theresa Harbig , Nils Gehlenborg

Scientists have been trying to identify all of the genes in the human genome since the initial draft of the genome was published in 2001. Over the intervening years, much progress has been made in identifying protein-coding genes, and the…

Nucleosome positioning is an important process required for proper genome packing and its accessibility to execute the genetic program in a cell-specific, timely manner. In the recent years hundreds of papers have been devoted to the…

Genomics · Quantitative Biology 2017-10-10 Vladimir B. Teif

We investigate the possibility of encoding multiple solutions of a problem in a single chromosome. The best solution encoded in an individual will represent (will provide the fitness of) that individual. In order to obtain some benefits the…

Neural and Evolutionary Computing · Computer Science 2021-10-22 Mihai Oltean

How to represent the genetic code? Despite the fact that it is extensively known, the DNA mapping into proteins remains as one of the relevant discoveries of genetics. However, modern genomic signal processing usually requires converting…

Other Quantitative Biology · Quantitative Biology 2015-03-10 H. M. de Oliveira , N. S. Santos-Magalhaes

Contouring is an indispensable step in Radiotherapy (RT) treatment planning. However, today's contouring software is constrained to only work with a 2D display, which is less intuitive and requires high task loads. Virtual Reality (VR) has…

Human-Computer Interaction · Computer Science 2022-11-09 Chen Chen , Matin Yarmand , Varun Singh , Michael V. Sherer , James D. Murphy , Yang Zhang , Nadir Weibel
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