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The Cancer Registry of Norway (CRN) is a part of the Norwegian Institute of Public Health (NIPH) and is tasked with producing statistics on cancer among the Norwegian population. For this task, CRN develops, tests, and evolves a software…

Software Engineering · Computer Science 2024-11-08 Xinyi Wang , Shaukat Ali , Paolo Arcaini , Narasimha Raghavan Veeraragavan , Jan F. Nygård

The Cancer Registry of Norway (CRN) collects, curates, and manages data related to cancer patients in Norway, supported by an interactive, human-in-the-loop, socio-technical decision support software system. Automated software testing of…

Software Engineering · Computer Science 2023-11-07 Christoph Laaber , Tao Yue , Shaukat Ali , Thomas Schwitalla , Jan F. Nygård

The Cancer Registry of Norway (CRN) collects and processes cancer-related data for patients in Norway. For this, it employs a sociotechnical software system that evolves with changing requirements and medical standards. The current practice…

Software Engineering · Computer Science 2024-12-17 Christoph Laaber , Shaukat Ali , Thomas Schwitalla , Jan F. Nygård

Automating data extraction from clinical documents offers significant potential to improve efficiency in healthcare settings, yet deploying Natural Language Processing (NLP) solutions presents practical challenges. Drawing upon our…

Computation and Language · Computer Science 2025-08-18 Lovedeep Gondara , Gregory Arbour , Raymond Ng , Jonathan Simkin , Shebnum Devji

The presence of detailed clinical information in electronic health record (EHR) systems presents promising prospects for enhancing patient care through automated retrieval techniques. Nevertheless, it is widely acknowledged that accessing…

Information Retrieval · Computer Science 2024-09-13 Abderrahim Oussama Batouche , Eugen Czeizler , Miika Koskinen , Tuomas Mirtti , Antti Sakari Rannikko

The Cancer Registry of Norway (CRN) uses an automated cancer registration support system (CaReSS) to support core cancer registry activities, i.e, data capture, data curation, and producing data products and statistics for various…

Software Engineering · Computer Science 2025-03-03 Erblin Isaku , Christoph Laaber , Hassan Sartaj , Shaukat Ali , Thomas Schwitalla , Jan F. Nygård

In modern cancer research, the vast volume of medical data generated is often underutilised due to challenges related to patient privacy. The OncoReg Challenge addresses this issue by enabling researchers to develop and validate image…

Skin cancer is a common problem in Australia and indeed around the world. Within the domain of e-Health, there appears to be no satisfactory clinical software that follows the flow of a normal skin cancer examination. This paper introduces…

Computers and Society · Computer Science 2018-08-20 Ahmed D. Alharthi , Peter Busch , Stephen Smith

This research focuses on evaluating and enhancing data readiness for the development of an Artificial Intelligence (AI)-based Clinical Decision Support System (CDSS) in the context of skin cancer treatment. The study, conducted at the Skin…

Artificial Intelligence · Computer Science 2025-03-13 Joscha Grüger , Tobias Geyer , Tobias Brix , Michael Storck , Sonja Leson , Laura Bley , Carsten Weishaupt , Ralph Bergmann , Stephan A. Braun

Cancer remains one of the most challenging diseases to treat in the medical field. Machine learning has enabled in-depth analysis of rich multi-omics profiles and medical imaging for cancer diagnosis and prognosis. Despite these…

Machine Learning · Computer Science 2024-01-15 Lingchao Mao , Hairong Wang , Leland S. Hu , Nhan L Tran , Peter D Canoll , Kristin R Swanson , Jing Li

Precision medicine is an emerging approach for disease treatment and prevention that delivers personalized care to individual patients by considering their genetic makeups, medical histories, environments, and lifestyles. Despite the rapid…

Machine Learning · Computer Science 2021-11-11 William Briguglio , Parisa Moghaddam , Waleed A. Yousef , Issa Traore , Mohammad Mamun

Data cleaning consumes about 80% of the time spent on data analysis for clinical research projects. This is a much bigger problem in the era of big data and machine learning in the field of medicine where large volumes of data are being…

Medical Physics · Physics 2018-01-03 Timothy Rozario , Troy Long , Mingli Chen , Weiguo Lu , Steve Jiang

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Personalized head and neck cancer therapeutics have greatly improved survival rates for patients, but are often leading to understudied long-lasting symptoms which affect quality of life. Sequential rule mining (SRM) is a promising…

Human-Computer Interaction · Computer Science 2023-09-28 Carla Floricel , Andrew Wentzel , Abdallah Mohamed , C. David Fuller , Guadalupe Canahuate , G. Elisabeta Marai

The advent of large scale, high-throughput genomic screening has introduced a wide range of tests for diagnostic purposes. Prominent among them are tests using miRNA expression levels. Genomics and proteomics now provide expression levels…

Genomics · Quantitative Biology 2016-11-08 Neerja Garikipati

Single-cell technologies have revolutionized biomedical research by enabling scalable measurement of the genome, transcriptome, and proteome of multiple systems at single-cell resolution. Now widely applied to cancer models, these assays…

Genomics · Quantitative Biology 2020-05-05 Allen W Zhang , Kieran R Campbell

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

Image and Video Processing · Electrical Eng. & Systems 2022-10-24 Solene Bechelli

Electronic medical records (EMRs) are critical, highly sensitive private information in healthcare, and need to be frequently shared among peers. Blockchain provides a shared, immutable and transparent history of all the transactions to…

Computers and Society · Computer Science 2017-09-20 Alevtina Dubovitskaya , Zhigang Xu , Samuel Ryu , Michael Schumacher , Fusheng Wang

Carcinoma is the prevailing type of cancer and can manifest in various body parts. It is widespread and can potentially develop in numerous locations within the body. In the medical domain, data for carcinoma cancer is often limited or…

Computer Vision and Pattern Recognition · Computer Science 2024-09-18 Kislay Raj , Teerath Kumar , Alessandra Mileo , Malika Bendechache
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