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Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Denoising diffusion probabilistic models (DDPMs) have achieved unprecedented success in computer vision. However, they remain underutilized in medical imaging, a field crucial for disease diagnosis and treatment planning. This is primarily…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Hongxu Jiang , Muhammad Imran , Teng Zhang , Yuyin Zhou , Muxuan Liang , Kuang Gong , Wei Shao

Positron range (PR) limits spatial resolution and quantitative accuracy in PET imaging, particularly for high-energy positron-emitting radionuclides like 68Ga. We propose a deep learning method using 3D residual encoder-decoder…

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

Given the potential X-ray radiation risk to the patient, low-dose CT has attracted a considerable interest in the medical imaging field. The current main stream low-dose CT methods include vendor-specific sinogram domain filtration and…

Medical Physics · Physics 2017-12-12 Hu Chen , Yi Zhang , Mannudeep K. Kalra , Feng Lin , Yang Chen , Peixi Liao , Jiliu Zhou , Ge Wang

Computed tomography (CT) is widely used in scientific imaging systems such as synchrotron and laboratory-based nano-CT, but acquiring full-view sinograms requires high radiation dose and long scan times. Sparse-view CT reduces this burden…

Image and Video Processing · Electrical Eng. & Systems 2026-02-10 Jiaze E , Srutarshi Banerjee , Tekin Bicer , Guannan Wang , Yanfu Zhang , Bin Ren

By decomposing the image formation process into a sequential application of denoising autoencoders, diffusion models (DMs) achieve state-of-the-art synthesis results on image data and beyond. Additionally, their formulation allows for a…

Computer Vision and Pattern Recognition · Computer Science 2022-04-14 Robin Rombach , Andreas Blattmann , Dominik Lorenz , Patrick Esser , Björn Ommer

Our aim was to enhance visual quality and quantitative accuracy of dynamic positron emission tomography (PET)uptake images by improved image reconstruction, using sophisticated sparse penalty models that incorporate both 2D spatial+1D…

Computer Vision and Pattern Recognition · Computer Science 2019-06-17 Ida Häggström , Yizun Lin , Si Li , Andrzej Krol , Yuesheng Xu , C. Ross Schmidtlein

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Combining dual-energy computed tomography (DECT) with positron emission tomography (PET) offers many potential clinical applications but typically requires expensive hardware upgrades or increases radiation doses on PET/CT scanners due to…

Medical Physics · Physics 2024-06-21 Siqi Li , Yansong Zhu , Benjamin A. Spencer , Guobao Wang

Low-dose computed tomography (CT) has attracted a major attention in the medical imaging field, since CT-associated x-ray radiation carries health risks for patients. The reduction of CT radiation dose, however, compromises the…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Yi Zhang , Qingsong Yang , Uwe Kruger , Mannudeep K. Kalra , Ling Sun , Wenxiang Cong , Ge Wang

Magnetic resonance imaging (MRI)-based synthetic computed tomography (sCT) simplifies radiation therapy treatment planning by eliminating the need for CT simulation and error-prone image registration, ultimately reducing patient radiation…

Image and Video Processing · Electrical Eng. & Systems 2023-06-01 Shaoyan Pan , Elham Abouei , Jacob Wynne , Tonghe Wang , Richard L. J. Qiu , Yuheng Li , Chih-Wei Chang , Junbo Peng , Justin Roper , Pretesh Patel , David S. Yu , Hui Mao , Xiaofeng Yang

In clinical practice, single-radiotracer positron emission tomography (PET) is commonly used for imaging. Although multi-tracer PET imaging can provide supplementary information of radiotracers that are sensitive to physiological function…

Image and Video Processing · Electrical Eng. & Systems 2025-06-23 Bin Huang , Feihong Xu , Xinchong Shi , Shan Huang , Binxuan Li , Fei Li , Qiegen Liu

Utilizing a low-dose CT approach significantly reduces the radiation exposure for patients, yet it introduces challenges, such as increased noise and artifacts in the resultant images, which can hinder accurate medical diagnostics.…

Image and Video Processing · Electrical Eng. & Systems 2024-04-03 Helena Shawn , Thompson Chyrikov , Jacob Lanet , Lam-chi Chen , Jim Zhao , Christina Chajo

The imaging performance of a high-resolution preclinical microPET system employing liquid xenon as the gamma ray detection medium was simulated. The arrangement comprises a ring of detectors consisting of trapezoidal LXe time projection…

Medical Physics · Physics 2012-03-23 A. Miceli , J. Glister , A. Andreyev , D. Bryman , L. Kurchaninov , P. Lu , A. Muennich , F. Retiere , V. Sossi

Nuclear image has emerged as a promising research work in medical field. Images from different modality meet its own challenge. Positron Emission Tomography (PET) image may help to precisely localize disease to assist in planning the right…

Computer Vision and Pattern Recognition · Computer Science 2013-03-05 A. Meena , R. Raja

Low-light photography produces images with low signal-to-noise ratios due to limited photons. In such conditions, common approximations like the Gaussian noise model fall short, and many denoising techniques fail to remove noise…

Computer Vision and Pattern Recognition · Computer Science 2025-07-08 Liying Lu , Raphaël Achddou , Sabine Süsstrunk

This study presents FP-PET, a comprehensive approach to medical image segmentation with a focus on CT and PET images. Utilizing a dataset from the AutoPet2023 Challenge, the research employs a variety of machine learning models, including…

Computer Vision and Pattern Recognition · Computer Science 2023-09-25 Yixin Chen , Ourui Fu , Wenrui Shao , Zhaoheng Xie

Access to high-quality datasets in the medical industry limits machine learning model performance. To address this issue, we propose a Denoising Diffusion Probabilistic Model (DDPM) combined with a UNet architecture for X-ray image…

Image and Video Processing · Electrical Eng. & Systems 2024-01-04 Praveen Mahaulpatha , Thulana Abeywardane , Tomson George

Working from a Poisson-Gaussian noise model, a multi-sample extension of the Photon Counting Histogram Expectation Maximization (PCH-EM) algorithm is derived as a general-purpose alternative to the Photon Transfer (PT) method. This…

Instrumentation and Detectors · Physics 2024-03-08 Aaron J. Hendrickson , David P. Haefner , Stanley H. Chan , Nicholas R. Shade , Eric R. Fossum