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Vertex Models, as used to describe cellular tissue, have an energy controlled by deviations of each cell area and perimeter from target values. The constrained nonlinear relation between area and perimeter leads to new mechanical response.…

Soft Condensed Matter · Physics 2022-07-04 Arthur Hernandez , Michael F. Staddon , Mark J. Bowick , M. Cristina Marchetti , Michael Moshe

The vertex model of epithelia describes the apical surface of a tissue as a tiling of polygonal cells, with a mechanical energy governed by deviations in cell shape from preferred, or target, area, $A_0$, and perimeter, $P_0$. The model…

Soft Condensed Matter · Physics 2023-04-12 Michael F. Staddon , Arthur Hernandez , Mark J. Bowick , Michael Moshe , M. Cristina Marchetti

Image acquisition techniques such as micro-computed tomography are nowadays widely available. Quantitative analysis of the resulting 3D image data enables geometric characterization of the micro-structure of materials. Stochastic geometry…

Numerical Analysis · Mathematics 2025-01-28 Anne Jung , Claudia Redenbach , Katja Schladitz , Sarah Staub

The elastic moduli of four numerical random isotropic packings of Hertzian spheres are studied. The four samples are assembled with different preparation procedures, two of which aim to reproduce experimental compaction by vibration and…

Materials Science · Physics 2007-11-19 I. Agnolin , J. -N. Roux

Animal morphogenesis often involves significant shape changes of epithelial tissue sheets. Great progress has been made in understanding the underlying cellular driving forces and their coordination through biomechanical feedback loops.…

Soft Condensed Matter · Physics 2024-09-23 Nikolas H. Claussen , Fridtjof Brauns

Cell extrusion is an essential mechanism for controlling cell density in epithelial tissues. Another essential element of epithelia is curvature, which is required to achieve complex shapes, like in the lung or intestine. Here we introduce…

In the perspective of developing smart hybrid materials with customized features, ferrogels and magnetorheological elastomers allow a synergy of elasticity and magnetism. The interplay between elastic and magnetic properties gives rise to a…

Soft Condensed Matter · Physics 2016-10-12 Giorgio Pessot , Hartmut Löwen , Andreas M. Menzel

The origin of rigidity in disordered materials is an outstanding open problem in statistical physics. Previously, a class of 2D cellular models has been shown to undergo a rigidity transition controlled by a mechanical parameter that…

Soft Condensed Matter · Physics 2023-01-18 Matthias Merkel , Lisa Manning

The shape assumed by a slender elastic structure is a function both of the geometry of the space in which it exists and the forces it experiences. We explore by experiments and theoretical analysis, the morphological phase-space of a…

Soft Condensed Matter · Physics 2023-12-11 S Ganga Prasath , Joel Marthelot , Rama Govindarajan , Narayanan Menon

Using a mean field approach and simulation, we study the non-linear mechanical response of the vertex model (VM) of biological tissue under compression and dilation. The VM is known to exhibit a transition between rigid and fluid-like, or…

Soft Condensed Matter · Physics 2023-03-14 Arthur Hernandez , Michael F. Staddon , Michael Moshe , M. Cristina Marchetti

We consider a model of an elastic manifold driven on a disordered energy landscape, with generalized long range elasticity. Varying the form of the elastic kernel by progressively allowing for the existence of zero-modes, the model…

Disordered Systems and Neural Networks · Physics 2019-11-27 E. E. Ferrero , E. A. Jagla

Living cells respond to mechanical changes in the matrix surrounding them by applying contractile forces that are in turn transmitted to distant cells. We calculate the mechanical work that each cell performs in order to deform the matrix,…

Soft Condensed Matter · Physics 2021-08-17 Chaviva Sirote , Yair Shokef

Morphogenesis involves complex shape changes of biological tissues. Yet, tissue shape changes depend on tissue rheology, which in turn arises from the interplay of large numbers of cells. Here, we link cell- and tissue-scale mechanics by…

Soft Condensed Matter · Physics 2026-02-27 Shalabh Kumar Anand , Matthias Merkel

Vertex models have been extensively used for simulating the evolution of multicellular systems, and have given rise to important global properties concerning their macroscopic rheology or jamming transitions. These models are based on the…

Soft Condensed Matter · Physics 2023-06-30 Ahmad K. Khan , Cécilia Olivesi , Jose J. Muñoz

One of the central appealing properties of magnetic gels and elastomers is that their elastic moduli can reversibly be adjusted from outside by applying magnetic fields. The impact of the internal magnetic particle distribution on this…

Soft Condensed Matter · Physics 2014-10-22 Giorgio Pessot , Peet Cremer , Dmitry Y. Borin , Stefan Odenbach , Hartmut Löwen , Andreas M. Menzel

We study equilibrium configurations for the Euler-Plateau energy with elastic modulus, which couples an energy functional of Euler-Plateau type with a total curvature term often present in models for the free energy of biomembranes. It is…

Differential Geometry · Mathematics 2020-10-02 Anthony Gruber , Álvaro Pámpano , Magdalena Toda

The paper addresses the problem of finding the necessary and sufficient conditions to be satisfied by the engineering moduli of an anisotropic material for the elastic energy to be positive for each state of strain or stress. The problem is…

Classical Physics · Physics 2024-04-29 Paolo Vannucci

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

This paper presents a phase-field model for simulating the three-dimensional deformation of vesicle membranes, incorporating area-difference elasticity, with constraints on bulk volume and surface area. We develop efficient numerical…

Numerical Analysis · Mathematics 2025-11-19 Yihong Liang , Emine Celiker , Ping Lin

While it is commonly observed that the shape dynamics of mammalian cells can undergo large random fluctuations, theoretical models aiming at capturing cell mechanics often focus on the deterministic part of the motion. In this paper, we…

Biological Physics · Physics 2021-04-07 Vikram Deshpande , Antonio DeSimone , Robert McMeeking , Pierre Recho
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