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Spatial transcriptomics assays are rapidly increasing in scale and complexity, making computational analysis a major bottleneck in biological discovery. Although frontier AI agents have improved dramatically at software engineering and…

Artificial Intelligence · Computer Science 2026-01-06 Kenny Workman , Zhen Yang , Harihara Muralidharan , Hannah Le

New telescopes like the Square Kilometre Array (SKA) will push into a new sensitivity regime and expose systematics, such as direction-dependent effects, that could previously be ignored. Current methods for handling such systematics rely…

Instrumentation and Methods for Astrophysics · Physics 2015-05-22 Michelle Lochner , Iniyan Natarajan , Jonathan T. L. Zwart , Oleg Smirnov , Bruce A. Bassett , Nadeem Oozeer , Martin Kunz

With the advent of the Square Kilometre Array Observatory (SKAO), scientists will be able to directly observe the Epoch of Reionization by mapping the distribution of neutral hydrogen at different redshifts. While physically motivated…

Cosmology and Nongalactic Astrophysics · Physics 2023-03-10 Damien Korber , Michele Bianco , Emma Tolley , Jean-Paul Kneib

This paper presents a dataset, called Reeds, for research on robot perception algorithms. The dataset aims to provide demanding benchmark opportunities for algorithms, rather than providing an environment for testing application-specific…

Computer Vision and Pattern Recognition · Computer Science 2021-09-20 Ola Benderius , Christian Berger , Krister Blanch

Many advances in astronomy and astrophysics originate from accurate images of the sky emission across multiple wavelengths. This often requires reconstructing spatially and spectrally correlated signals detected from multiple instruments.…

Instrumentation and Methods for Astrophysics · Physics 2024-09-17 Vincent Eberle , Matteo Guardiani , Margret Westerkamp , Philipp Frank , Julian Rüstig , Julia Stadler , Torsten A. Enßlin

Most applications of Bayesian Inference for parameter estimation and model selection in astrophysics involve the use of Monte Carlo techniques such as Markov Chain Monte Carlo (MCMC) and nested sampling. However, these techniques are time…

Instrumentation and Methods for Astrophysics · Physics 2022-01-26 Geetakrishnasai Gunapati , Anirudh Jain , P. K. Srijith , Shantanu Desai

Upcoming astronomical surveys such as the Large Synoptic Survey Telescope (LSST) will rely on photometric classification to identify the majority of the transients and variables that they discover. We present a set of techniques for…

Instrumentation and Methods for Astrophysics · Physics 2020-01-08 Kyle Boone

This study introduces an approach to detecting exocomet transits in the dataset of the Transiting Exoplanet Survey Satellite (TESS), specifically within its Sector 1. Given the limited number of exocomet transits detected in the observed…

Earth and Planetary Astrophysics · Physics 2024-03-01 D. V. Dobrycheva , M. Yu. Vasylenko , I. V. Kulyk , Ya. V. Pavlenko , O. S. Shubina , I. V. Luk'yanyk , P. P. Korsun

We present GalSBI, a phenomenological model of the galaxy population for cosmological applications using simulation-based inference. The model is based on analytical parametrizations of galaxy luminosity functions, morphologies and spectral…

Cosmology and Nongalactic Astrophysics · Physics 2025-06-09 Silvan Fischbacher , Tomasz Kacprzak , Luca Tortorelli , Beatrice Moser , Alexandre Refregier , Patrick Gebhardt , Daniel Gruen

While Bayesian inference provides a principled framework for reasoning under uncertainty, its widespread adoption is limited by the intractability of exact posterior computation, necessitating the use of approximate inference. However,…

Machine Learning · Statistics 2026-05-19 George Whittle , Juliusz Ziomek , Jacob Rawling , Maike A. Osborne

There is an increasing number of large, digital, synoptic sky surveys, in which repeated observations are obtained over large areas of the sky in multiple epochs. Likewise, there is a growth in the number of (often automated or robotic)…

One of the big challenges in astrophysics is the comparison of complex simulations to observations. As many codes do not directly generate observables (e.g. hydrodynamic simulations), the last step in the modelling process is often a…

Instrumentation and Methods for Astrophysics · Physics 2018-05-08 Frederik Beaujean , Hans C. Eggers , Wolfgang E. Kerzendorf

Karabo is a versatile Python-based software framework simplifying research with radio astronomy data. It bundles existing software packages into a coherent whole to improve the ease of use of its components. Karabo includes useful…

We develop a fast and scalable computational framework to solve large-scale and high-dimensional Bayesian optimal experimental design problems. In particular, we consider the problem of optimal observation sensor placement for Bayesian…

Numerical Analysis · Mathematics 2020-11-09 Keyi Wu , Peng Chen , Omar Ghattas

Cosmological inference becomes increasingly difficult when complex data-generating processes cannot be modeled by simple probability distributions. With the ever-increasing size of data sets in cosmology, there is increasing burden placed…

Cosmology and Nongalactic Astrophysics · Physics 2015-06-05 Anja Weyant , Chad Schafer , W. Michael Wood-Vasey

The Bright Transient Survey (BTS) aims to obtain a classification spectrum for all bright ($m_\mathrm{peak}\,\leq\,18.5\,$mag) extragalactic transients found in the Zwicky Transient Facility (ZTF) public survey. BTS critically relies on…

This paper introduces a framework for speeding up Bayesian inference conducted in presence of large datasets. We design a Markov chain whose transition kernel uses an (unknown) fraction of (fixed size) of the available data that is randomly…

Methodology · Statistics 2018-06-01 Florian Maire , Nial Friel , Pierre Alquier

Inference on time series data is a common requirement in many scientific disciplines and internet of things (IoT) applications, yet there are few resources available to domain scientists to easily, robustly, and repeatably build such…

Mathematical Software · Computer Science 2016-09-16 Brett Naul , Stéfan van der Walt , Arien Crellin-Quick , Joshua S. Bloom , Fernando Pérez

Approximate Bayesian Computation (ABC) methods have become essential tools for performing inference when likelihood functions are intractable or computationally prohibitive. However, their scalability remains a major challenge in…

Methodology · Statistics 2025-07-09 Antoine Luciano , Charly Andral , Christian P. Robert , Robin J. Ryder

Recent galaxy redshift surveys have brought in a large amount of accurate cosmological data out to redshift 0.3, and future surveys are expected to achieve a high degree of completeness out to a redshift exceeding 1. Consequently, a…

General Relativity and Quantum Cosmology · Physics 2008-11-26 Teresa Hui-Ching Lu , Charles Hellaby