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We apply logic-based machine learning techniques to facilitate cellular engineering and drive biological discovery, based on comprehensive databases of metabolic processes called genome-scale metabolic network models (GEMs). Predicted host…

Artificial Intelligence · Computer Science 2024-11-14 Lun Ai , Stephen H. Muggleton , Shi-shun Liang , Geoff S. Baldwin

High-throughput technologies such as next generation sequencing allow biologists to observe cell function with unprecedented resolution, but the resulting datasets are too large and complicated for humans to understand without the aid of…

Applications · Statistics 2021-10-08 David S. Watson

Solving Inductive Logic Programming (ILP) problems with neural networks is a key challenge in Neural-Symbolic Ar- tificial Intelligence (AI). While most research has focused on designing novel network architectures for individual prob-…

Artificial Intelligence · Computer Science 2025-11-18 Bowen He , Xiaoan Xu , Alper Kamil Bozkurt , Vahid Tarokh , Juncheng Dong

The capability of making interpretable and self-explanatory decisions is essential for developing responsible machine learning systems. In this work, we study the learning to explain problem in the scope of inductive logic programming…

Artificial Intelligence · Computer Science 2020-02-20 Yuan Yang , Le Song

One approach to explaining the hierarchical levels of understanding within a machine learning model is the symbolic method of inductive logic programming (ILP), which is data efficient and capable of learning first-order logic rules that…

Machine Learning · Computer Science 2023-09-01 Andreas Bueff , Vaishak Belle

The application of Artificial Intelligence (AI) to synthetic biology will provide the foundation for the creation of a high throughput automated platform for genetic design, in which a learning machine is used to iteratively optimise the…

Artificial Intelligence · Computer Science 2021-05-18 Wang-Zhou Dai , Liam Hallett , Stephen H. Muggleton , Geoff S. Baldwin

Reasoning about hypotheses and updating knowledge through empirical observations are central to scientific discovery. In this work, we applied logic-based machine learning methods to drive biological discovery by guiding experimentation.…

Molecular Networks · Quantitative Biology 2025-06-09 Lun Ai , Stephen H. Muggleton , Shi-Shun Liang , Geoff S. Baldwin

Recently deep reinforcement learning has achieved tremendous success in wide ranges of applications. However, it notoriously lacks data-efficiency and interpretability. Data-efficiency is important as interacting with the environment is…

Machine Learning · Computer Science 2021-06-23 Duo Xu , Faramarz Fekri

Despite recent advances in modern machine learning algorithms, the opaqueness of their underlying mechanisms continues to be an obstacle in adoption. To instill confidence and trust in artificial intelligence systems, Explainable Artificial…

Machine Learning · Computer Science 2023-03-06 Zheng Zhang , Liangliang Xu , Levent Yilmaz , Bo Liu

Inductive logic programming (ILP) is a form of logical machine learning. The goal is to search a hypothesis space for a hypothesis that generalises training examples and background knowledge. We introduce an approach that 'shrinks' the…

Artificial Intelligence · Computer Science 2026-05-18 Andrew Cropper , Filipe Gouveia , David M. Cerna

Inductive logic programming (ILP) has been a deeply influential paradigm in AI, enjoying decades of research on its theory and implementations. As a natural descendent of the fields of logic programming and machine learning, it admits the…

Artificial Intelligence · Computer Science 2020-01-16 Vaishak Belle

The modeling and simulation of high-dimensional multiscale systems is a critical challenge across all areas of science and engineering. It is broadly believed that even with today's computer advances resolving all spatiotemporal scales…

Machine Learning · Statistics 2023-09-13 Emmanuel Menier , Sebastian Kaltenbach , Mouadh Yagoubi , Marc Schoenauer , Petros Koumoutsakos

Despite the advancements in in-context learning (ICL) for large language models (LLMs), current research centers on specific prompt engineering, such as demonstration selection, with the expectation that a single iteration of demonstrations…

Computation and Language · Computer Science 2024-06-05 Jiaxi Yang , Binyuan Hui , Min Yang , Bailin Wang , Bowen Li , Binhua Li , Fei Huang , Yongbin Li

My research explores integrating deep learning and logic programming to set the basis for a new generation of AI systems. By combining neural networks with Inductive Logic Programming (ILP), the goal is to construct systems that make…

Logic in Computer Science · Computer Science 2025-02-14 Talissa Dreossi

Inductive logic programming (ILP) is a form of machine learning. The goal of ILP is to induce a hypothesis (a set of logical rules) that generalises training examples. As ILP turns 30, we provide a new introduction to the field. We…

Artificial Intelligence · Computer Science 2022-03-23 Andrew Cropper , Sebastijan Dumančić

To learn about real world phenomena, scientists have traditionally used models with clearly interpretable elements. However, modern machine learning (ML) models, while powerful predictors, lack this direct elementwise interpretability (e.g.…

Machine Learning · Statistics 2024-07-16 Timo Freiesleben , Gunnar König , Christoph Molnar , Alvaro Tejero-Cantero

The goal of Inductive Logic Programming (ILP) is to learn a program that explains a set of examples in the context of some pre-existing background knowledge. Until recently, most research on ILP targeted learning Prolog programs. Our own…

Artificial Intelligence · Computer Science 2020-05-05 Mark Law , Alessandra Russo , Krysia Broda

Inductive logic programming (ILP) is a form of logic-based machine learning. The goal is to induce a hypothesis (a logic program) that generalises given training examples. As ILP turns 30, we review the last decade of research. We focus on…

Artificial Intelligence · Computer Science 2021-09-23 Andrew Cropper , Sebastijan Dumančić , Richard Evans , Stephen H. Muggleton

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

Inductive Logic Programming (ILP) provides interpretable rule learning in relational domains, yet remains limited in its ability to induce and reason with numerical constraints. Classical ILP systems operate over discrete predicates and…

Artificial Intelligence · Computer Science 2025-12-16 Nijesh Upreti , Vaishak Belle
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