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In this study, we conduct a study on magnetic hyperthermia treatment when a vessel is located near the tumor. The holistic framework is established to solve the process of tumor treatment. The interstitial tissue fluid, MNP distribution,…

This study was undertaken to develop a system for heat transfer simulation for optimization and treatment planning of magnetic hyperthermia treatment (MHT) using magnetic particle imaging (MPI). First, we performed phantom experiments to…

Medical Physics · Physics 2016-05-27 Natsuo Banura , Atsushi Mimura , Kohei Nishimoto , Kenya Murase

High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…

Medical Physics · Physics 2020-07-14 Gajendra Singh , Anup Paul , Himanshu Shekhar , Abhijit Paul

During laser and ultrasound thermotherapy it is always desirable to have a precise necrosis of deeply seated tumor preserving the adjoining healthy tissue with minimum thermally induced nociceptive pain sensation to the patient. The aim of…

Medical Physics · Physics 2020-07-29 Abhijit Paul , Anup Paul

Heat-based cancer treatment, so-called hyperthermia, can be used to destroy tumour cells directly or to make them more susceptible to chemotherapy or radiation therapy. To apply heat locally, iron oxide nanoparticles are injected into the…

Computational Engineering, Finance, and Science · Computer Science 2025-02-04 Barbara Wirthl , Paolo Decuzzi , Bernhard A. Schrefler , Wolfgang A. Wall

We report a model for hyperthermia therapies based on heat diffusion in a biological tissue containing a topological defect. Biological tissues behave like active liquid crystals with the presence of topological defects which are likely to…

Statistical Mechanics · Physics 2024-10-02 Andy Manapany , Loriane Didier , Leïla Moueddene , Bertrand Berche , Sébastien Fumeron

We analyze the necrosis growth due to thermal coagulation induced by laser light absorption and limited by heat diffusion into the surrounding live tissue. The tissue is assumed to contain a certain tumor in the undamaged tissue whereof the…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 B. Y. Datsko , V. V. Gafiychuk , I. A. Lubashevsky , A. V. Priezzhev

We develop a multiphysics-based model to predict the response of localized tumors to combined-hyperthermia-radiotherapy (CHR) treatment. This procedure combines hyperthermia (tumor heating) with standard radiotherapy to improve efficacy of…

Tissues and Organs · Quantitative Biology 2019-07-05 Japan K. Patel , Richard Vasques , Barry D. Ganapol

Magnetic hyperthermia is a new type of cancer treatment designed for overcoming resistance to chemotherapy during the treatment of solid, inaccessible human tumors. The main challenge of this technology is increasing the local tumoral…

Tissues and Organs · Quantitative Biology 2016-11-09 Beatriz Sanz , M. Pilar Calatayud , Teobaldo E. Torres , Mónica L. Fanarraga , M. Ricardo Ibarra , Gerardo F. Goya

Fast and reliable monitoring of volumetric heat distribution during MRI-guided tumor ablation is an urgent clinical need. In this work, we introduce a method for generating 2.5D thermometry maps from uniformly distributed 2D MRI phase…

Image and Video Processing · Electrical Eng. & Systems 2021-12-01 Julian Alpers , Daniel L. Reimert , Maximilian Rötzer , Thomas Gerlach , Marcel Gutberlet , Frank Wacker , Bennet Hensen , Christian Hansen

Intracorporeal needle-based therapeutic ultrasound (NBTU) is a minimally invasive option for intervening in malignant brain tumors, commonly used in thermal ablation procedures. This technique is suitable for both primary and metastatic…

Magnetic nanoparticle hyperthermia is an attractive emerging cancer treatment, but the acting microscopic energy deposition mechanisms are not well understood and optimization suffers. We describe several approximate forms for the…

Mesoscale and Nanoscale Physics · Physics 2014-03-26 Daniel B. Reeves , John B. Weaver

A new model is considered to describe the evolution of tissue temperature and water concentration during a thermal ablation process. The aim of this study is to expand the results obtained in Blauth et. al. 2020, where the tissue water…

Analysis of PDEs · Mathematics 2023-12-22 Federico Herrero-Hervás , Angiolo Farina

Intracorporeal needle-based therapeutic ultrasound (NBTU) offers a minimally invasive approach for the thermal ablation of malignant brain tumors, including both primary and metastatic cancers. NBTU utilizes a high-frequency alternating…

Medical Physics · Physics 2024-09-11 Zhanyue Zhao , Yiwei Jiang , Charles Bales , Yang Wang , Gregory Fischer

Radiotherapy can effectively kill malignant cells, but the doses required to cure cancer patients may inflict severe collateral damage to adjacent healthy tissues. Hyperthermia (HT) is a promising option to improve the outcome of radiation…

Since decades, many techniques have been developed for curing cancer. Here, an effort has been made to cure tumor by inserting a cryoprobe into the target region which is connected to a cryogenic mechanism. This technique is presently used…

Medical Physics · Physics 2022-12-23 G Sai Krishna , Anup Paul

A simplified 2-D model which is an example of regional RF hyperthermia is presented. Human body is inside the wire with exciting current and the electromagnetic energy is concentrated within the tumor. The analyzed model is therefore a…

Medical Physics · Physics 2017-10-31 Piotr Gas

Multimodal oncological strategies which combine chemotherapy or radiotherapy with hyperthermia have a potential of improving the efficacy of the non-surgical methods of cancer treatment. Hyperthermia engages the heat-shock response…

Subcellular Processes · Quantitative Biology 2013-09-05 Mikołaj Rybiński , Zuzanna Szymańska , Sławomir Lasota , Anna Gambin

Hyperthermia therapy (HT) is used to treat diseases through heating of high temperature usually in conjunction with some other medical therapeutics like chemotherapy and radiotherapy. In this study, we propose a promising thermostatic…

Medical Physics · Physics 2021-09-14 Yuchan Wang , Yuening Wang , Yuan Jie , Paul Carson

Lasers are becoming a more and more important tool in cutting and shaping materials. Improving precision and effectivity is an ongoing demand in science and industry. One possibility are double pulses. Here we study laser ablation of…

Materials Science · Physics 2015-06-19 Johannes Roth , Armin Krauß , Jan Lotze , Hans-Rainer Trebin
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