Related papers: Parametric Investigation on Different Bone Densiti…
This study presents a computational optimisation framework of a hip implant through the development of a functionally graded biomimetic lattice structure, whose design was structurally optimised to limit stress shielding. The optimisation…
We introduce the Optimal Fingerprinting Process which is aimed at accurately identifying the parameters which characterize the dynamics of a physical system. A database is first built from the time evolution of an ensemble of dynamical…
In this work, the Theory of Porous Media (TPM) is employed to model percutaneous vertebroplasty, a medical procedure in which acrylic cement is injected into cancellous vertebral bone. Previously, isothermal macroscale models have been…
We construct optimal designs for estimating fetal malformation rate, prenatal death rate and an overall toxicity index in a toxicology study under a broad range of model assumptions. We use Weibull distributions to model these rates and…
Cementless implants are widely used in orthopedic and oral surgery. However, debonding-related failure still occurs at the bone-implant interface. It remains difficult to predict such implant failure since the underlying osseointegration…
Mechanical pain (or mechanical algesia) can both be a vital mechanism warning us for dangers or an undesired medical symptom important to mitigate. Thus, a comprehensive understanding of the different mechanisms of this type of pain is…
In this work we present the design of a new test geometry inspired by the Tapered Double Cantilever Beam (TDCB) specimen that is shown to provide an improved characterization of the fracture properties of brittle solids. First, we show that…
Accelerated destructive degradation test (ADDT) is a technique that is commonly used by industries to access material's long-term properties. In many applications, the accelerating variable is usually the temperature. In such cases, a…
Achieving an optimal biomechanical environment within bone scaffolds is critical for promoting tissue regeneration, particularly in load-bearing anatomical sites where rigid fixation can induce stress shielding and compromise healing.…
Density Functional Theory (DFT) has become a cornerstone in the modeling of metals. However, accurately simulating metals, particularly under extreme conditions, presents two significant challenges. First, simulating complex metallic…
Vision processing on traditional architectures is inefficient due to energy-expensive off-chip data movement. Many researchers advocate pushing processing close to the sensor to substantially reduce data movement. However, continuous…
Designing topological materials with specific topological indices is a complex inverse problem, traditionally tackled through manual, intuition-driven methods that are neither scalable nor efficient for exploring the vast space of possible…
A three-way coupled thermo-mechanical fracture model is presented to predict the damage of brittle ceramics, in particular {\alpha}-SiC, over a wide range of temperatures (20-1400 C). Predicting damage over such a range of temperatures is…
The fracture behavior of brittle and ductile materials can be strongly influenced by thermal fluctuations, especially in micro- and nano-devices as well as in rubberlike and biological materials. However, temperature effects, in particular…
Cells and tissues are constantly exposed to various chemical and physical signals that intricately regulate various physiological and pathological processes. This study explores the integration of two biophysical methods, Traction Force…
Segmentation is a fundamental task in medical image analysis. The clinical interest is often to measure the volume of a structure. To evaluate and compare segmentation methods, the similarity between a segmentation and a predefined ground…
This work is concerned with the numerical simulation of ablation of geological materials using a millimetre wave source. To this end, a new mathematical model is developed for a thermal approach to the problem, allowing for large scale…
For bone segmentation, the classical geodesic active contour model is usually limited by its indiscriminate feature extraction, and then struggles to handle the phenomena of edge obstruction, edge leakage and bone fracture. Thus, we propose…
This paper introduces a method for estimating the shape and location of an embedded tumor. The approach utilizes shape optimization techniques, applying the coupled complex boundary method. By rewriting the problem -- characterized by a…
Damage models for ductile materials typically need to be parameterized, often with the appropriate parameters changing for a given material depending on the loading conditions. This can make parameterizing these models computationally…