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Cardiovascular diseases (CVD) are the leading cause of death globally. Non-invasive, cost-effective imaging techniques play a crucial role in early detection and prevention of CVD. Optical coherence tomography (OCT) has gained recognition…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Cynthia Maldonado-Garcia , Rodrigo Bonazzola , Enzo Ferrante , Thomas H Julian , Panagiotis I Sergouniotis , Nishant Ravikumara , Alejandro F Frangi

Coronary artery stenosis is a critical health risk, and its precise identification in Coronary Angiography (CAG) can significantly aid medical practitioners in accurately evaluating the severity of a patient's condition. The complexity of…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 In Kyu Lee , Junsup Shin , Yong-Hee Lee , Jonghoe Ku , Hyun-Woo Kim

Assessing coronary artery plaque segments in coronary CT angiography scans is an important task to improve patient management and clinical outcomes, as it can help to decide whether invasive investigation and treatment are necessary. In…

Aortic stenosis (AS) is the most common valvular heart disease in developed countries. High-fidelity preclinical models can improve AS management by enabling therapeutic innovation, early diagnosis, and tailored treatment planning. However,…

Computational Engineering, Finance, and Science · Computer Science 2024-07-02 Caglar Ozturk , Daniel H. Pak , Luca Rosalia , Debkalpa Goswami , Mary E. Robakowski , Raymond McKay , Christopher T. Nguyen , James S. Duncan , Ellen T. Roche

Diagnostic investigation has an important role in risk stratification and clinical decision making of patients with suspected and documented Coronary Artery Disease (CAD). However, the majority of existing tools are primarily focused on the…

Background: AI-driven prediction algorithms have the potential to enhance emergency medicine by enabling rapid and accurate decision-making regarding patient status and potential deterioration. However, the integration of multimodal data,…

Machine Learning · Computer Science 2025-05-02 Juan Miguel Lopez Alcaraz , Hjalmar Bouma , Nils Strodthoff

Most of the functions performed by astrocytes in brain information processing are related to calcium waves. Experimental studies involving calcium waves present discrepant results, leading to gaps in the full understanding of the functions…

Biological Physics · Physics 2021-07-09 Thais Appelt Peres Bartiê , Leonel Teixeira Pinto

Multi-omics data, that is, datasets containing different types of high-dimensional molecular variables (often in addition to classical clinical variables), are increasingly generated for the investigation of various diseases. Nevertheless,…

Machine Learning · Statistics 2020-12-22 Moritz Herrmann , Philipp Probst , Roman Hornung , Vindi Jurinovic , Anne-Laure Boulesteix

Explainable Artificial Intelligence (XAI) has been identified as a viable method for determining the importance of features when making predictions using Machine Learning (ML) models. In this study, we created models that take an…

Quantitative Methods · Quantitative Biology 2021-12-28 Isaac Ronald Ward , Ling Wang , Juan lu , Mohammed Bennamoun , Girish Dwivedi , Frank M Sanfilippo

The adverse effects of microgravity exposure on mammalian physiology during spaceflight necessitate a deep understanding of the underlying mechanisms to develop effective countermeasures. One such concern is muscle atrophy, which is partly…

Background: Photoplethysmography (PPG), increasingly available through wearable devices, provides a non-invasive means of monitoring human hemodynamics. In this study, we introduce artificial intelligence-derived photoplethysmography…

Signal Processing · Electrical Eng. & Systems 2025-09-26 Guangkun Nie , Qinghao Zhao , Gongzheng Tang , Yaxin Li , Shenda Hong

Cardiac diseases are among the leading causes of morbidity and mortality worldwide, which requires accurate and timely diagnostic strategies. In this study, we introduce an innovative approach that combines deep learning image registration…

Machine Learning · Computer Science 2025-07-09 Comte Valentin , Gemma Piella , Mario Ceresa , Miguel A. Gonzalez Ballester

This study evaluates two approaches applied to computed tomography (CT) images of patients with abdominal aortic aneurysm: one deterministic, based on tools of Approximation Theory, and one based on Artificial Intelligence. Both aim to…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Lucrezia Rinelli , Arianna Travaglini , Nicolò Vescera , Gianluca Vinti

Advanced AI systems offer substantial benefits but also introduce risks. In 2025, AI-enabled cyber offense has emerged as a concrete example. This technical report applies a quantitative risk modeling methodology (described in full in a…

Purpose of Review Recently, machine learning has developed rapidly in the field of medicine, playing an important role in disease diagnosis. Our aim of this paper is to provide an overview of the advancements in machine learning techniques…

Medical Physics · Physics 2024-05-15 Pukar Baral , Chen Zhao , Michele Esposito , Weihua Zhou

Cardiovascular Diseases (CVD) and strokes produce immense health and economic burdens globally. Coronary Artery Disease (CAD) is the most common type of cardiovascular disease. Coronary Angiography, which is an invasive treatment, is also…

Artificial Intelligence · Computer Science 2020-05-22 Ioannis Apostolopoulos , Peter Groumpos

Atherosclerosis, a chronic inflammatory disease affecting the large arteries, presents a global health risk. Accurate analysis of diagnostic images, like computed tomographic angiograms (CTAs), is essential for staging and monitoring the…

Image and Video Processing · Electrical Eng. & Systems 2023-11-28 Alireza Bagheri Rajeoni , Breanna Pederson , Daniel G. Clair , Susan M. Lessner , Homayoun Valafar

Advanced Ovarian Cancer (AOC) is often diagnosed at an advanced stage with peritoneal carcinosis (PC). Fagotti score (FS) assessment at diagnostic laparoscopy (DL) guides treatment planning by estimating surgical resectability, but its…

Computational fluid dynamics (CFD) based simulation of coronary blood flow provides valuable hemodynamic markers, such as pressure gradients, for diagnosing coronary artery disease (CAD). However, CFD is computationally expensive,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Rene Lisasi , Michele Esposito , Chen Zhao

Accurate segmentation of coronary arteries remains a significant challenge in clinical practice, hindering the ability to effectively diagnose and manage coronary artery disease. The lack of large, annotated datasets for model training…

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