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Incidental detection and quantification of coronary calcium in CT scans could lead to the early introduction of lifesaving clinical interventions. However, over-reporting could negatively affect patient wellbeing and unnecessarily burden…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Olivier Jaubert , Salman Mohammadi , Keith A. Goatman , Shadia S. Mikhael , Conor Bradley , Rebecca Hughes , Richard Good , John H. Hipwell , Sonia Dahdouh

The Agatston score, which is the sum of the calcification in the four main coronary arteries, has been widely used in the diagnosis of coronary artery disease (CAD). However, many studies have emphasized the importance of the…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Doyoung Park , Jinsoo Kim , Qi Chang , Shuang Leng , Liang Zhong , Lohendran Baskaran

Cardiovascular disease (CVD) is a common and strong threat to human beings, featuring high prevalence, disability and mortality. The amount of coronary artery calcification (CAC) is an effective factor for CVD risk evaluation.…

Image and Video Processing · Electrical Eng. & Systems 2019-07-29 Jiechao Ma , Rongguo Zhang

Coronary calcium causes beam hardening and blooming artifacts on cardiac computed tomography angiography (CTA) images, which lead to overestimation of lumen stenosis and reduction of diagnostic specificity. To properly remove coronary…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Siming Yan , Feng Shi , Yuhua Chen , Damini Dey , Sang-Eun Lee , Hyuk-Jae Chang , Debiao Li , Yibin Xie

This case study details The University of Texas Medical Branch (UTMB)'s partnership with Zauron Labs, Inc. to enhance detection and coding of aortic calcifications (ACs) using chest radiographs. ACs are often underreported despite their…

Image and Video Processing · Electrical Eng. & Systems 2025-09-30 Eric Walser , Peter McCaffrey , Kal Clark , Nicholas Czarnek

We report an object tracking algorithm that combines geometrical constraints, thresholding, and motion detection for tracking of the descending aorta and the network of major arteries that branch from the aorta including the iliac and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-19 Liang Zhao , Brendan Odigwe , Susan Lessner , Daniel G. Clair , Firas Mussa , Homayoun Valafar

Cardiovascular disease (CVD) is the global leading cause of death. A strong risk factor for CVD events is the amount of coronary artery calcium (CAC). To meet demands of the increasing interest in quantification of CAC, i.e. coronary…

Computer Vision and Pattern Recognition · Computer Science 2021-09-09 Bob D. de Vos , Jelmer M. Wolterink , Tim Leiner , Pim A. de Jong , Nikolas Lessmann , Ivana Isgum

Cardiovascular Diseases (CVDs) are the leading cause of death worldwide, taking 17.9 million lives annually. Abdominal Aortic Calcification (AAC) is an established marker for CVD, which can be observed in lateral view Vertebral Fracture…

Computer Vision and Pattern Recognition · Computer Science 2024-09-27 Zaid Ilyas , Afsah Saleem , David Suter , Siobhan Reid , John Schousboe , William Leslie , Joshua Lewis , Syed Zulqarnain Gilani

Coronary artery calcification (CAC) is a strong predictor of cardiovascular events, with CT-based Agatston scoring widely regarded as the clinical gold standard. However, CT is costly and impractical for large-scale screening, while chest…

Computer Vision and Pattern Recognition · Computer Science 2026-01-07 Dylan Saeed , Ramtin Gharleghi , Susann Beier , Sonit Singh

Coronary artery calcification (CAC) is a strong and independent predictor of cardiovascular disease (CVD). However, manual assessment of CAC often requires radiological expertise, time, and invasive imaging techniques. The purpose of this…

Computer Vision and Pattern Recognition · Computer Science 2024-02-16 Andrew M. Nguyen , Jianfei Liu , Tejas Sudharshan Mathai , Peter C. Grayson , Ronald M. Summers

We analyze the Agatston score of coronary artery calcium (CAC) from the Multi-Ethnic Study of Atherosclerosis (MESA) using the semiparametric zero-inflated modeling approach, where the observed CAC scores from this cohort consist of high…

Applications · Statistics 2012-10-02 Hai Liu , Shuangge Ma , Richard Kronmal , Kung-Sik Chan

The accuracy of coronary artery disease (CAD) diagnosis is dependent on a variety of factors, including demographic, symptom, and medical examination, ECG, and echocardiography data, among others. In this context, artificial intelligence…

Artificial Intelligence · Computer Science 2023-08-30 Elham Nasarian , Danial Sharifrazi , Saman Mohsenirad , Kwok Tsui , Roohallah Alizadehsani

Coronary artery calcium (CAC) scoring from chest CT is a well-established tool to stratify and refine clinical cardiovascular disease risk estimation. CAC quantification relies on the accurate delineation of calcified lesions, but is…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Xinran Gong , Gorkem Durak , Halil Ertugrul Aktas , Vedat Cicek , Jinkui Hao , Ulas Bagci , Nilay S. Shah , Bo Zhou

As a potential non-invasive biomarker for ischaemic stroke, intracranial arterial calcification (IAC) could be used for stroke risk assessment on CT head scans routinely acquired for other reasons (e.g. trauma, confusion). Artificial…

Image and Video Processing · Electrical Eng. & Systems 2025-07-03 Benjamin Jin , Maria del C. Valdés Hernández , Alessandro Fontanella , Wenwen Li , Eleanor Platt , Paul Armitage , Amos Storkey , Joanna M. Wardlaw , Grant Mair

Heavy smokers undergoing screening with low-dose chest CT are affected by cardiovascular disease as much as by lung cancer. Low-dose chest CT scans acquired in screening enable quantification of atherosclerotic calcifications and thus…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Nikolas Lessmann , Bram van Ginneken , Majd Zreik , Pim A. de Jong , Bob D. de Vos , Max A. Viergever , Ivana Išgum

Our long-range goal is to improve current whole-heart CT calcium score by extracting quantitative features from individual calcifications. We performed deconvolution to improve small calcifications assessment which challenge conventional CT…

Traditional echocardiographic parameters such as ejection fraction (EF) and global longitudinal strain (GLS) have limitations in the early detection of cardiac dysfunction. EF often remains normal despite underlying pathology, and GLS is…

Machine Learning · Computer Science 2025-07-21 Beka Begiashvili , Carlos J. Fernandez-Candel , Matías Pérez Paredes

Background: Invasive coronary arteriography (ICA) is recognized as the gold standard for diagnosing cardiovascular diseases, including unstable angina (UA). The challenge lies in determining the optimal timing for ICA in UA patients,…

Machine Learning · Computer Science 2024-08-09 Candi Zheng , Kun Liu , Yang Wang , Shiyi Chen , Hongli Li

Coronary artery disease remains one of the leading causes of mortality globally. Despite advances in revascularization treatments like PCI and CABG, postoperative stroke is inevitable. This study aims to develop and evaluate a sophisticated…

Machine Learning · Computer Science 2025-03-18 Haonan Pan , Shuheng Chen , Elham Pishgar , Kamiar Alaei , Greg Placencia , Maryam Pishgar

Background: While intravascular imaging, particularly optical coherence tomography (OCT), improves percutaneous coronary intervention (PCI) outcomes, its interpretation is operator-dependent. General-purpose artificial intelligence (AI)…