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Human brain development is a complex and dynamic process that begins during the first weeks of pregnancy and lasts until early adulthood. This chapter focuses on the developmental window from prenatal period to infancy, probably the most…

Neurons and Cognition · Quantitative Biology 2025-05-01 Arnaud Cachia , Jean-François Mangin , Jessica Dubois

As more connectome data become available, the question of how to best analyse the structure of biological neural networks becomes increasingly pertinent. In brain networks, knowing that two areas are connected is often not sufficient, as…

Neurons and Cognition · Quantitative Biology 2024-01-30 Tanguy Fardet , Emmanouil Giannakakis , Lukas Paulun , Anna Levina

Dynamic networks have been increasingly used to characterize brain connectivity that varies during resting and task states. In such characterizations, a connectivity network is typically measured at each time point for a subject over a…

Methodology · Statistics 2023-03-23 Maoyu Zhang , Biao Cai , Wenlin Dai , Dehan Kong , Hongyu Zhao , Jingfei Zhang

Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

The distributed nature of the neural substrate, and the difficulty of establishing necessity from correlative data, combine to render the mapping of brain function a far harder task than it seems. Methods capable of combining connective…

The structural network of the brain, or structural connectome, can be represented by fiber bundles generated by a variety of tractography methods. While such methods give qualitative insights into brain structure, there is controversy over…

Computer Vision and Pattern Recognition · Computer Science 2022-06-15 Kristen M. Campbell , Haocheng Dai , Zhe Su , Martin Bauer , P. Thomas Fletcher , Sarang C. Joshi

The human brains are organized into hierarchically modular networks facilitating efficient and stable information processing and supporting diverse cognitive processes during the course of development. While the remarkable reconfiguration…

Neurons and Cognition · Quantitative Biology 2020-09-16 Xuyun Wen , Liming Hsu , Weili Lin , Han Zhang , Dinggang Shen

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

Neurons and Cognition · Quantitative Biology 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Neural network oscillations are a fundamental mechanism for cognition, perception and consciousness. Consequently, perturbations of network activity play an important role in the pathophysiology of brain disorders. When structural…

Neurons and Cognition · Quantitative Biology 2016-04-29 Timothée Proix , Fabrice Bartolomei , Maxime Guye , Viktor K. Jirsa

The premature fusion of cranial bones, craniosynostosis, affects the correct development of the skull producing morphological malformations in newborns. To assess the susceptibility of each craniofacial articulation to close prematurely, we…

Tissues and Organs · Quantitative Biology 2016-12-28 Borja Esteve-Altava , Toni Valles-Catala , Roger Guimera , Marta Sales-Pardo , Diego Rasskin-Gutman

Autism spectrum disorder (ASD) is one of the major developmental disorders affecting children. Recently, it has been hypothesized that ASD is associated with atypical brain connectivities. A substantial body of researches use Pearson's…

Neurons and Cognition · Quantitative Biology 2019-03-06 Biwei Huang , Kun Zhang , Ruben Sanchez-Romero , Joseph Ramsey , Madelyn Glymour , Clark Glymour

Understanding the evolution of brain functional networks over time is of great significance for the analysis of cognitive mechanisms and the diagnosis of neurological diseases. Existing methods often have difficulty in capturing the…

Machine Learning · Computer Science 2025-10-30 Tianqi Guo , Liping Chen , Ciyuan Peng , Jingjing Zhou , Jing Ren

Despite differences in brain sizes and cognitive niches among mammals, their cerebral cortices posses many common features and regularities. These regularities have been a subject of experimental investigation in neuroanatomy for the last…

Neurons and Cognition · Quantitative Biology 2007-05-23 Jan Karbowski

The understanding of the convoluted evolution of infant brain networks during the first postnatal year is pivotal for identifying the dynamics of early brain connectivity development. Existing deep learning solutions suffer from three major…

Neurons and Cognition · Quantitative Biology 2024-01-09 Michalis Pistos , Gang Li , Weili Lin , Dinggang Shen , Islem Rekik

Structural and functional neuroimaging modalities provide complementary windows into brain organization: structural imaging characterizes neural tissue anatomy and microstructure, while functional imaging captures dynamic patterns of neural…

Methodology · Statistics 2026-03-24 Sakul Mahat , Sharmistha Guha , Jessica Bernard

Recent cellular-level volumetric brain reconstructions have revealed high levels of anatomic complexity. Determining which structural aspects of the brain to focus on, especially when comparing with computational models and other organisms,…

Disordered Systems and Neural Networks · Physics 2023-09-29 Helen S. Ansell , István A. Kovács

Understanding brain connectivity in a network-theoretic context has shown much promise in recent years. This type of analysis identifies brain organisational principles, bringing a new perspective to neuroscience. At the same time, large…

Neural and Evolutionary Computing · Computer Science 2016-11-28 Sarah Parisot , Jonathan Passerat-Palmbach , Markus D. Schirmer , Boris Gutman

Background: The treatment of depressive episodes is well established, with clearly demonstrated effectiveness of antidepressants and psychotherapies. However, more than one-third of depressed patients do not respond to treatment.…

Neurons and Cognition · Quantitative Biology 2024-03-29 Sébastien Dam , Jean-Marie Batail , Gabriel H Robert , Dominique Drapier , Pierre Maurel , Julie Coloigner

There is a growing interest in using diffusion MRI to study the white matter tracts and structural connectivity of the fetal brain. Recent progress in data acquisition and processing suggests that this imaging modality has a unique role in…

Neurons and Cognition · Quantitative Biology 2024-08-09 Camilo Calixto , Matheus D. Soldatelli , Bo Li , Lana Pierotich , Ali Gholipour , Simon K. Warfield , Davood Karimi

Brain networks characterize complex connectivities among brain regions as graph structures, which provide a powerful means to study brain connectomes. In recent years, graph neural networks have emerged as a prevalent paradigm of learning…

Machine Learning · Computer Science 2022-06-10 Yi Yang , Yanqiao Zhu , Hejie Cui , Xuan Kan , Lifang He , Ying Guo , Carl Yang
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