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Representation learning on electronic health records (EHRs) plays a vital role in downstream medical prediction tasks. Although natural language processing techniques, such as recurrent neural networks, and self-attention, have been adapted…

Artificial Intelligence · Computer Science 2026-01-12 Xueping Peng , Guodong Long , Tao Shen , Sen Wang , Chengqi Zhang , Allison Clarke , Clement Schlegel

In medical information extraction, medical Named Entity Recognition (NER) is indispensable, playing a crucial role in developing medical knowledge graphs, enhancing medical question-answering systems, and analyzing electronic medical…

Computation and Language · Computer Science 2024-03-26 Xiaojing Du , Hanjie Zhao , Danyan Xing , Yuxiang Jia , Hongying Zan

This study addresses a critical gap in the healthcare system by developing a clinically meaningful, practical, and explainable disease surveillance system for multiple chronic diseases, utilizing routine EHR data from multiple U.S.…

Machine Learning · Computer Science 2025-01-28 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Ahmad Abdullah , Ibrahim Hashmat , Muddassar Farooq

Forecasting how a patient's condition is likely to evolve, including possible deterioration, recovery, treatment needs, and care transitions, could support more proactive and personalized care, but requires modeling heterogeneous and…

Machine Learning · Computer Science 2026-03-26 Chantal Pellegrini , Ege Özsoy , David Bani-Harouni , Matthias Keicher , Nassir Navab

Effective representation learning of electronic health records is a challenging task and is becoming more important as the availability of such data is becoming pervasive. The data contained in these records are irregular and contain…

Machine Learning · Computer Science 2020-05-05 Sajad Darabi , Mohammad Kachuee , Shayan Fazeli , Majid Sarrafzadeh

There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance…

Machine Learning · Statistics 2017-03-27 Long Ho , David Ledbetter , Melissa Aczon , Randall Wetzel

Objective: Machine learning (ML) predictive models are often developed without considering downstream value trade-offs and clinical interpretability. This paper introduces a cost-aware prediction (CAP) framework that combines cost-benefit…

Machine Learning · Computer Science 2025-11-20 Yinan Yu , Falk Dippel , Christina E. Lundberg , Martin Lindgren , Annika Rosengren , Martin Adiels , Helen Sjöland

The recent wide adoption of Electronic Medical Records (EMR) presents great opportunities and challenges for data mining. The EMR data is largely temporal, often noisy, irregular and high dimensional. This paper constructs a novel ordinal…

Applications · Statistics 2014-07-24 Truyen Tran , Dinh Phung , Wei Luo , Svetha Venkatesh

In the healthcare sector, the application of deep learning technologies has revolutionized data analysis and disease forecasting. This is particularly evident in the field of diabetes, where the deep analysis of Electronic Health Records…

Machine Learning · Computer Science 2024-12-06 Huadong Pang , Li Zhou , Yiping Dong , Peiyuan Chen , Dian Gu , Tianyi Lyu , Hansong Zhang

Accurate and interpretable mortality risk prediction in intensive care units (ICUs) remains a critical challenge due to the irregular temporal structure of electronic health records (EHRs), the complexity of longitudinal disease…

Machine Learning · Computer Science 2026-03-10 Zahra Jafari , Azadeh Zamanifar , Amirfarhad Farhadi

Proactive analysis of patient pathways helps healthcare providers anticipate treatment-related risks, identify outcomes, and allocate resources. Machine learning (ML) can leverage a patient's complete health history to make informed…

Machine Learning · Computer Science 2024-05-24 Sandra Zilker , Sven Weinzierl , Mathias Kraus , Patrick Zschech , Martin Matzner

Electronic Health Records (EHRs) provide a rich, longitudinal view of patient health and hold significant potential for advancing clinical decision support, risk prediction, and data-driven healthcare research. However, most artificial…

The inherent complexity of structured longitudinal Electronic Health Records (EHR) data poses a significant challenge when integrated with Large Language Models (LLMs), which are traditionally tailored for natural language processing.…

Computation and Language · Computer Science 2024-02-13 Yinghao Zhu , Zixiang Wang , Junyi Gao , Yuning Tong , Jingkun An , Weibin Liao , Ewen M. Harrison , Liantao Ma , Chengwei Pan

Machine learning holds great promise for advancing the field of medicine, with electronic health records (EHRs) serving as a primary data source. However, EHRs are often sparse and contain missing data due to various challenges and…

Machine Learning · Computer Science 2026-02-25 Jun Han , Josue Nassar , Sanjit Singh Batra , Aldo Cordova-Palomera , Vijay Nori , Robert E. Tillman

The widespread adoption of electronic health records (EHRs) enables the acquisition of heterogeneous clinical data, spanning lab tests, vital signs, medications, and procedures, which offer transformative potential for artificial…

Signal Processing · Electrical Eng. & Systems 2026-03-17 Mingcheng Zhu , Yu Liu , Zhiyao Luo , Tingting Zhu

In this work, we introduce the Multiple Embedding Model for EHR (MEME), an approach that serializes multimodal EHR tabular data into text using pseudo-notes, mimicking clinical text generation. This conversion not only preserves better…

Computation and Language · Computer Science 2025-07-08 Simon A. Lee , Sujay Jain , Alex Chen , Kyoka Ono , Jennifer Fang , Akos Rudas , Jeffrey N. Chiang

Artificial intelligence (AI) tools for radiology are commonly unmonitored once deployed. The lack of real-time case-by-case assessments of AI prediction confidence requires users to independently distinguish between trustworthy and…

Causal inference from electronic health records (EHR) is fundamentally limited by unmeasured confounding: critical clinical states such as frailty, goals of care, and mental status are documented in free-text notes but absent from…

Machine Learning · Computer Science 2026-04-22 Lei Liu , Jialin Chen , Kathy Macropol

We present RAM-EHR, a Retrieval AugMentation pipeline to improve clinical predictions on Electronic Health Records (EHRs). RAM-EHR first collects multiple knowledge sources, converts them into text format, and uses dense retrieval to obtain…

Computation and Language · Computer Science 2024-07-30 Ran Xu , Wenqi Shi , Yue Yu , Yuchen Zhuang , Bowen Jin , May D. Wang , Joyce C. Ho , Carl Yang

We present a self-supervised, time-to-event (TTE) foundation model called MOTOR (Many Outcome Time Oriented Representations) which is pretrained on timestamped sequences of events in electronic health records (EHR) and health insurance…

Machine Learning · Computer Science 2023-12-06 Ethan Steinberg , Jason Fries , Yizhe Xu , Nigam Shah
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