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Spatiotemporal graph represents a crucial data structure where the nodes and edges are embedded in a geometric space and can evolve dynamically over time. Nowadays, spatiotemporal graph data is becoming increasingly popular and important,…

Machine Learning · Computer Science 2022-03-02 Yuanqi Du , Xiaojie Guo , Hengning Cao , Yanfang Ye , Liang Zhao

Many natural systems, such as neurons firing in the brain or basketball teams traversing a court, give rise to time series data with complex, nonlinear dynamics. We can gain insight into these systems by decomposing the data into segments…

Understanding how decision making changes across the lifespan is a central challenge for neuroscience, yet research on cognitive aging has remained largely disconnected from the theoretical and computational advances that now shape modern…

Neurons and Cognition · Quantitative Biology 2026-03-04 Michael B. Ryan , Letizia Ye , Anne K. Churchland

Function and dysfunctions of neural systems are tied to the temporal evolution of neural states. The current limitations in showing their causal role stem largely from the absence of tools capable of probing the brain's internal state in…

Neurons and Cognition · Quantitative Biology 2024-09-24 Ayesha Vermani , Matthew Dowling , Hyungju Jeon , Ian Jordan , Josue Nassar , Yves Bernaerts , Yuan Zhao , Steven Van Vaerenbergh , Il Memming Park

Motivation: Several different threads of research have been proposed for modeling and mining temporal data. On the one hand, approaches such as dynamic Bayesian networks (DBNs) provide a formal probabilistic basis to model relationships…

Machine Learning · Computer Science 2009-04-15 Debprakash Patnaik , Srivatsan Laxman , Naren Ramakrishnan

Whether, when, and how causal interactions between neurons can be meaningfully studied from observations of neural activity alone are vital questions in neural data analysis. Here we aim to better outline the concept of functional…

Neurons and Cognition · Quantitative Biology 2023-12-05 Ian H. Stevenson

In this paper, we use augmented the hierarchical latent variable model to model multi-period time series, where the dynamics of time series are governed by factors or trends in multiple periods. Previous methods based on stacked recurrent…

Neural and Evolutionary Computing · Computer Science 2018-10-25 Daniel Hsu

How do humans and animals perform trial-and-error learning when the space of possibilities is infinite? In a previous study, we used an interval timing production task and discovered an updating strategy in which the agent adjusted the…

Neurons and Cognition · Quantitative Biology 2022-05-10 Jing Wang , Yousuf El-Jayyousi , Ilker Ozden

This paper considers neural representation through the lens of active inference, a normative framework for understanding brain function. It delves into how living organisms employ generative models to minimize the discrepancy between…

Neurons and Cognition · Quantitative Biology 2023-10-24 Giovanni Pezzulo , Leo D'Amato , Francesco Mannella , Matteo Priorelli , Toon Van de Maele , Ivilin Peev Stoianov , Karl Friston

Characterizing time-evolving networks is a challenging task, but it is crucial for understanding the dynamic behavior of complex systems such as the brain. For instance, how spatial networks of functional connectivity in the brain evolve…

Applications · Statistics 2021-01-27 Marie Roald , Suchita Bhinge , Chunying Jia , Vince Calhoun , Tülay Adalı , Evrim Acar

Recent research is revealing how cognitive processes are supported by a complex interplay between the brain and the rest of the body, which can be investigated by the analysis of physiological features such as breathing rhythms, heart rate,…

Quantitative Methods · Quantitative Biology 2023-03-10 Fernando E. Rosas , Diego Candia-Rivera , Andrea I Luppi , Yike Guo , Pedro A. M. Mediano

The statistical analysis of group studies in neuroscience is particularly challenging due to the complex spatio-temporal nature of the data, its multiple levels and the inter-individual variability in brain responses. In this respect,…

Methodology · Statistics 2025-05-15 Nicolò Margaritella , Vanda Inácio , Ruth King

Recent advances in experimental techniques enable the simultaneous recording of activity from thousands of neurons in the brain, presenting both an opportunity and a challenge: to build meaningful, scalable models of large neural…

Biological Physics · Physics 2025-08-05 Luca Di Carlo , Francesca Mignacco , Christopher W. Lynn , William Bialek

Hierarchical model fitting has become commonplace for case-control studies of cognition and behaviour in mental health. However, these techniques require us to formalise assumptions about the data-generating process at the group level,…

Computers and Society · Computer Science 2020-11-04 Vincent Valton , Toby Wise , Oliver J. Robinson

Connectomics and network neuroscience offer quantitative scientific frameworks for modeling and analyzing networks of structurally and functionally interacting neurons, neuronal populations, and macroscopic brain areas. This shift in…

Neurons and Cognition · Quantitative Biology 2020-10-06 Richard Betzel

From interacting cellular components to networks of neurons and neural systems, interconnected units comprise a fundamental organizing principle of the nervous system. Understanding how their patterns of connections and interactions give…

Neurons and Cognition · Quantitative Biology 2018-08-01 Danielle S. Bassett , Perry Zurn , Joshua I. Gold

Emerging technologies are revealing the spiking activity in ever larger neural ensembles. Frequently, this spiking is far from independent, with correlations in the spike times of different cells. Understanding how such correlations impact…

Neurons and Cognition · Quantitative Biology 2013-05-20 James Trousdale , Yu Hu , Eric Shea-Brown , Krešimir Josić

Variational inference has had great success in scaling approximate Bayesian inference to big data by exploiting mini-batch training. To date, however, this strategy has been most applicable to models of independent data. We propose an…

Machine Learning · Statistics 2021-05-19 Tom Ryder , Dennis Prangle , Andrew Golightly , Isaac Matthews

The ubiquity of multiscale interactions in complex systems is well-recognized, with development and heredity serving as a prime example of how processes at different temporal scales influence one another. This work introduces a novel…

Signal Processing · Electrical Eng. & Systems 2024-09-04 Nayely Vélez-Cruz , Manfred D. Laubichler

Neural circuits contain heterogeneous groups of neurons that differ in type, location, connectivity, and basic response properties. However, traditional methods for dimensionality reduction and clustering are ill-suited to recovering the…

Machine Learning · Statistics 2016-10-27 Scott W. Linderman , Ryan P. Adams , Jonathan W. Pillow