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Federated techniques such as federated learning and federated analysis have emerged as a powerful paradigm for enabling multi-center research on sensitive clinical data while preserving patient privacy. In this study, we introduce a…

Machine Learning · Computer Science 2026-05-12 Evelyn Trautmann , Joël Federer-Gsponer , Markus C. Elze , José-Tomás Prieto

In the past few decades, machine learning has revolutionized data processing for large scale applications. Simultaneously, increasing privacy threats in trending applications led to the redesign of classical data training models. In…

Machine Learning · Computer Science 2021-07-26 Muhammad Asad , Ahmed Moustafa , Takayuki Ito

The escalating influx of data generated by networked edge devices, coupled with the growing awareness of data privacy, has restricted the traditional data analytics workflow, where the edge data are gathered by a centralized server to be…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-08 Zibo Wang , Haichao Ji , Yifei Zhu , Dan Wang , Zhu Han

Epidemic surveillance is a challenging task, especially when crucial data is fragmented across institutions and data custodians are unable or unwilling to share it. This study aims to explore the feasibility of a simple federated…

Applications · Statistics 2024-09-17 Ruiqi Lyu , Roni Rosenfeld , Bryan Wilder

We address the goal of conducting inference about a smooth finite-dimensional parameter by utilizing individual-level data from various independent sources. Recent advancements have led to the development of a comprehensive theory capable…

Statistics Theory · Mathematics 2025-11-19 Ellen Graham , Marco Carone , Andrea Rotnitzky

Deep Learning has established in the latest years as a successful approach to address a great variety of tasks. Healthcare is one of the most promising field of application for Deep Learning approaches since it would allow to help…

Machine Learning · Computer Science 2021-10-05 Edoardo Giacomello , Michele Cataldo , Daniele Loiacono , Pier Luca Lanzi

With the recent bloom of data, there is a huge surge in threats against individuals' private information. Various techniques for optimizing privacy-preserving data analysis are at the focus of research in the recent years. In this paper, we…

Cryptography and Security · Computer Science 2022-11-11 Sayan Biswas , Graham Cormode , Carsten Maple

We examine the combination of two directions in the field of privacy concerning computations over distributed private inputs - secure function evaluation (SFE) and differential privacy. While in both the goal is to privately evaluate some…

Cryptography and Security · Computer Science 2011-03-15 Amos Beimel , Kobbi Nissim , Eran Omri

Deep learning models have shown their advantage in many different tasks, including neuroimage analysis. However, to effectively train a high-quality deep learning model, the aggregation of a significant amount of patient information is…

Machine Learning · Computer Science 2020-12-08 Xiaoxiao Li , Yufeng Gu , Nicha Dvornek , Lawrence Staib , Pamela Ventola , James S. Duncan

Federated learning has emerged as a powerful framework for analysing distributed data, yet two challenges remain pivotal: heterogeneity across sites and privacy of local data. In this paper, we address both challenges within a federated…

Machine Learning · Computer Science 2026-04-07 Mengchu Li , Ye Tian , Yang Feng , Yi Yu

Federated learning is a data decentralization privacy-preserving technique used to perform machine or deep learning in a secure way. In this paper we present theoretical aspects about federated learning, such as the presentation of an…

Machine Learning · Computer Science 2022-11-09 Judith Sáinz-Pardo Díaz , Álvaro López García

As the sequencing costs are decreasing, there is great incentive to perform large scale association studies to increase power of detecting new variants. Federated association testing among different institutions is a viable solution for…

Methodology · Statistics 2022-10-04 Wentao Li , Han Chen , Xiaoqian Jiang , Arif Harmanci

Federated clustering (FC) is an extension of centralized clustering in federated settings. The key here is how to construct a global similarity measure without sharing private data, since the local similarity may be insufficient to group…

Machine Learning · Computer Science 2023-10-24 Jie Yan , Jing Liu , Ji Qi , Zhong-Yuan Zhang

In the traditional distributed machine learning scenario, the user's private data is transmitted between clients and a central server, which results in significant potential privacy risks. In order to balance the issues of data privacy and…

Distributed, Parallel, and Cluster Computing · Computer Science 2022-12-20 Zihao Zhao , Yuzhu Mao , Yang Liu , Linqi Song , Ye Ouyang , Xinlei Chen , Wenbo Ding

Machine learning has become integral to medical research and is increasingly applied in clinical settings to support diagnosis and decision-making; however, its effectiveness depends on access to large, diverse datasets, which are limited…

Machine Learning · Computer Science 2026-04-21 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

We consider industrial federated learning, a collaboration between a small number of powerful, potentially competing industrial players, mediated by a third party aspiring to improve the service it provides to its customers. We argue that…

Machine Learning · Computer Science 2024-09-24 David Brunner , Alessio Montuoro

As deep learning have been applied in a clinical context, privacy concerns have increased because of the collection and processing of a large amount of personal data. Recently, federated learning (FL) has been suggested to protect personal…

Machine Learning · Computer Science 2020-05-26 GeunHyeong Lee , Soo-Yong Shin

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

The rapid emergence of massive datasets in various fields poses a serious challenge to traditional statistical methods. Meanwhile, it provides opportunities for researchers to develop novel algorithms. Inspired by the idea of…

Computation · Statistics 2023-04-14 Yuan Gao , Weidong Liu , Hansheng Wang , Xiaozhou Wang , Yibo Yan , Riquan Zhang

Suppose we have individual data from an internal study and various summary statistics from relevant external studies. External summary statistics have the potential to improve statistical inference for the internal population; however, it…

Methodology · Statistics 2026-02-06 Wenjie Hu , Ruoyu Wang , Wei Li , Wang Miao