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Optical coherence tomography (OCT) imaging is a well-known technology for visualizing retinal layers and helps ophthalmologists to detect possible diseases. Accurate and early diagnosis of common retinal diseases can prevent the patients…

Retinal vessels are important biomarkers for many ophthalmological and cardiovascular diseases. Hence, it is of great significance to develop automatic models for computer-aided diagnosis. Existing methods, such as U-Net follow the…

Segmentation is a fundamental task in medical image analysis. However, most existing methods focus on primary region extraction and ignore edge information, which is useful for obtaining accurate segmentation. In this paper, we propose a…

Glaucoma is a disease in which the optic nerve is chronically damaged by the elevation of the intra-ocular pressure, resulting in visual field defect. Therefore, it is important to monitor and treat suspected patients before they are…

Automatic retinal layer segmentation with medical images, such as optical coherence tomography (OCT) images, serves as an important tool for diagnosing ophthalmic diseases. However, it is challenging to achieve accurate segmentation due to…

In recent years, medical image segmentation has become an important application in the field of computer-aided diagnosis. In this paper, we are the first to propose a new graph convolution-based decoder namely, Cascaded Graph Convolutional…

We propose an encoder-decoder framework for the segmentation of blood vessels in retinal images that relies on the extraction of large-scale patches at multiple image-scales during training. Experiments on three fundus image datasets…

Organ at risk (OAR) segmentation in computed tomography (CT) imagery is a difficult task for automated segmentation methods and can be crucial for downstream radiation treatment planning. U-net has become a de-facto standard for medical…

Optical Coherence Tomography (OCT) provides valuable insights in ophthalmology, cardiology, and neurology due to high-resolution, cross-sectional images of the retina. One critical task for ophthalmologists using OCT is delineation of…

Although deep encoder-decoder networks have achieved astonishing performance for mitochondria segmentation from electron microscopy (EM) images, they still produce coarse segmentations with lots of discontinuities and false positives.…

We develop a novel deep contour detection algorithm with a top-down fully convolutional encoder-decoder network. Our proposed method, named TD-CEDN, solves two important issues in this low-level vision problem: (1) learning multi-scale and…

The Encoder-Decoder architecture is a main stream deep learning model for biomedical image segmentation. The encoder fully compresses the input and generates encoded features, and the decoder then produces dense predictions using encoded…

Image co-segmentation has attracted a lot of attentions in computer vision community. In this paper, we propose a new approach to image co-segmentation through introducing the dense connections into the decoder path of Siamese U-net and…

Glaucoma is the leading cause of irreversible blindness in people over the age of 60, accounting for 6.6 to 8% of all blindness in 2010, but there is still much to be learned about the genetic origins of the eye disease. With the modern…

Diabetic Retinopathy (DR) is a leading cause of blindness in working age adults. DR lesions can be challenging to identify in fundus images, and automatic DR detection systems can offer strong clinical value. Of the publicly available…

Diabetic Retinopathy (DR) is a primary cause of blindness, necessitating early detection and diagnosis. This paper focuses on referable DR classification to enhance the applicability of the proposed method in clinical practice. We develop…

Colonoscopy is a procedure to detect colorectal polyps which are the primary cause for developing colorectal cancer. However, polyp segmentation is a challenging task due to the diverse shape, size, color, and texture of polyps, shuttle…

Purpose: To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods: A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1…

Pulmonary nodule detection plays an important role in lung cancer screening with low-dose computed tomography (CT) scans. It remains challenging to build nodule detection deep learning models with good generalization performance due to…

The lethal nature of pancreatic ductal adenocarcinoma (PDAC) calls for early differential diagnosis of pancreatic cysts, which are identified in up to 16% of normal subjects, and some of which may develop into PDAC. Previous computer-aided…