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The diagnosis of prostate cancer is challenging due to the heterogeneity of its presentations, leading to the over diagnosis and treatment of non-clinically important disease. Accurate diagnosis can directly benefit a patient's quality of…

The success of deep learning heavily depends on the availability of large labeled training sets. However, it is hard to get large labeled datasets in medical image domain because of the strict privacy concern and costly labeling efforts.…

Computer Vision and Pattern Recognition · Computer Science 2021-09-30 Dewen Zeng , Yawen Wu , Xinrong Hu , Xiaowei Xu , Haiyun Yuan , Meiping Huang , Jian Zhuang , Jingtong Hu , Yiyu Shi

Non-invasive prostate cancer detection from MRI has the potential to revolutionize patient care by providing early detection of clinically-significant disease (ISUP grade group >= 2), but has thus far shown limited positive predictive…

Image and Video Processing · Electrical Eng. & Systems 2022-12-14 Abhejit Rajagopal , Antonio C. Westphalen , Nathan Velarde , Tim Ullrich , Jeffry P. Simko , Hao Nguyen , Thomas A. Hope , Peder E. Z. Larson , Kirti Magudia

Background and Objective: Given the high heterogeneity and clinical diversity of cancer, substantial variations exist in multi-omics data and clinical features across different cancer subtypes. Methods: We propose a model, named DEDUCE,…

Machine Learning · Computer Science 2024-10-29 Liangrui Pan , Xiang Wang , Qingchun Liang , Jiandong Shang , Wenjuan Liu , Liwen Xu , Shaoliang Peng

Current deep learning-based models typically analyze medical images in either 2D or 3D albeit disregarding volumetric information or suffering sub-optimal performance due to the anisotropic resolution of MR data. Furthermore, providing an…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Alex Ling Yu Hung , Haoxin Zheng , Kai Zhao , Kaifeng Pang , Demetri Terzopoulos , Kyunghyun Sung

Recent studies have demonstrated the superior performance of introducing ``scan-wise" contrast labels into contrastive learning for multi-organ segmentation on multi-phase computed tomography (CT). However, such scan-wise labels are…

Computer Vision and Pattern Recognition · Computer Science 2022-10-18 Ho Hin Lee , Yucheng Tang , Han Liu , Yubo Fan , Leon Y. Cai , Qi Yang , Xin Yu , Shunxing Bao , Yuankai Huo , Bennett A. Landman

We hypothesize that anatomical priors can be viable mediums to infuse domain-specific clinical knowledge into state-of-the-art convolutional neural networks (CNN) based on the U-Net architecture. We introduce a probabilistic population…

Image and Video Processing · Electrical Eng. & Systems 2021-09-22 Anindo Saha , Matin Hosseinzadeh , Henkjan Huisman

Recent advances in medical imaging techniques have led to significant improvements in the management of prostate cancer (PCa). In particular, multi-parametric MRI (mp-MRI) continues to gain clinical acceptance as the preferred imaging…

Image and Video Processing · Electrical Eng. & Systems 2019-10-08 Ruiming Cao , Xinran Zhong , Fabien Scalzo , Steven Raman , Kyung hyun Sung

Homologous anatomical landmarks between medical scans are instrumental in quantitative assessment of image registration quality in various clinical applications, such as MRI-ultrasound registration for tissue shift correction in…

Computer Vision and Pattern Recognition · Computer Science 2023-07-28 Soorena Salari , Amirhossein Rasoulian , Hassan Rivaz , Yiming Xiao

Pre-biopsy magnetic resonance imaging (MRI) is increasingly used to target suspicious prostate lesions. This has led to artificial intelligence (AI) applications improving MRI-based detection of clinically significant prostate cancer…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Hassan Jahanandish , Shengtian Sang , Cynthia Xinran Li , Sulaiman Vesal , Indrani Bhattacharya , Jeong Hoon Lee , Richard Fan , Geoffrey A. Sonna , Mirabela Rusu

Contrastive learning has gained popularity and pushes state-of-the-art performance across numerous large-scale benchmarks. In contrastive learning, the contrastive loss function plays a pivotal role in discerning similarities between…

Computer Vision and Pattern Recognition · Computer Science 2025-12-03 Haojin Deng , Yimin Yang

Data augmentation (DA) is a key factor in medical image analysis, such as in prostate cancer (PCa) detection on magnetic resonance images. State-of-the-art computer-aided diagnosis systems still rely on simplistic spatial transformations to…

Prostate Cancer (PCa) is a prevalent disease among men, and multi-parametric MRIs offer a non-invasive method for its detection. While MRI-based deep learning solutions have shown promise in supporting PCa diagnosis, acquiring sufficient…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Meng Zhou , Amoon Jamzad , Jason Izard , Alexandre Menard , Robert Siemens , Parvin Mousavi

We investigate the connection between visual semantic features defined in PI-RADS and associated risk factors, moving beyond abnormal imaging findings, establishing a shared framework between medical and AI professionals by creating a…

This paper proposes an Incremental Learning (IL) approach to enhance the accuracy and efficiency of deep learning models in analyzing T2-weighted (T2w) MRI medical images prostate cancer detection using the PI-CAI dataset. We used multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-04-29 Sara Yavari , Jacob Furst

Deep learning-based diagnostic performance increases with more annotated data, but large-scale manual annotations are expensive and labour-intensive. Experts evaluate diagnostic images during clinical routine, and write their findings in…

Image and Video Processing · Electrical Eng. & Systems 2024-07-01 Joeran S. Bosma , Anindo Saha , Matin Hosseinzadeh , Ilse Slootweg , Maarten de Rooij , Henkjan Huisman

Objective: To develop and evaluate a deep radiomics model for clinically significant prostate cancer (csPCa, grade group >= 2) detection and compare its performance to Prostate Imaging Reporting and Data System (PI-RADS) assessment in a…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 G. A. Nketiah , M. R. Sunoqrot , E. Sandsmark , S. Langørgen , K. M. Selnæs , H. Bertilsson , M. Elschot , T. F. Bathen

Micro-ultrasound (micro-US) is a promising imaging technique for cancer detection and computer-assisted visualization. This study investigates prostate capsule segmentation using deep learning techniques from micro-US images, addressing the…

Image and Video Processing · Electrical Eng. & Systems 2025-09-22 Kaniz Fatema , Vaibhav Thakur , Emad A. Mohammed

Dimension reduction is an essential tool for analyzing high dimensional data. Most existing methods, including principal component analysis (PCA), as well as their extensions, provide principal components that are often linear combinations…

Methodology · Statistics 2025-08-18 Eric Zhang , Michael Love , Didong Li

Many current neural networks for medical imaging generalise poorly to data unseen during training. Such behaviour can be caused by networks overfitting easy-to-learn, or statistically dominant, features while disregarding other potentially…

Image and Video Processing · Electrical Eng. & Systems 2022-12-05 Joona Pohjonen , Carolin Stürenberg , Antti Rannikko , Tuomas Mirtti , Esa Pitkänen