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Scientists in some fields are concerned that many, or even most, published results are false. A high rate of false positives might arise accidentally, from shoddy research practices. Or it might be the inevitable result of institutional…

Physics and Society · Physics 2020-03-03 Alexander J. Stewart , Joshua B. Plotkin

Discovering interpretable physical laws from high-dimensional data is a fundamental challenge in scientific research. Traditional methods, such as symbolic regression, often produce complex, unphysical formulas when searching a vast space…

Computational Physics · Physics 2026-02-27 Yifeng Guan , Chuyi Liu , Dongzhan Zhou , Lei Bai , Wan-jian Yin , Jingyuan Li , Mao Su

We survey some of our recent results on inverse problems for evolution equations. The goal is to provide a unified approach to solve various types of evolution equations. The inverse problems we consider consist in determining unknown…

Analysis of PDEs · Mathematics 2019-12-09 Kaïs Ammari , Mourad Choulli , Faouzi Triki

A vast array of transformative technologies developed over the past decade has enabled measurement and perturbation at ever increasing scale, yet our understanding of many systems remains limited by experimental capacity. Overcoming this…

Quantitative Methods · Quantitative Biology 2020-12-25 Brian Cleary , Aviv Regev

Scientific evidence often spans instruments, databases, and disciplines, so no single source records the full phenomenon. This makes it difficult to determine when coordinated AI agents add value over simpler scientific workflows. We…

Artificial Intelligence · Computer Science 2026-05-22 Fiona Y. Wong , Markus J. Buehler

Modern scientific simulations, observations, and large-scale experiments generate data at volumes that often exceed the limits of storage, processing, and analysis. This challenge drives the development of data reduction methods that…

Machine Learning · Computer Science 2025-11-18 Minh Vu , Andrey Lokhov

Artificial intelligence (AI) models trained on published scientific findings have been used to invent valuable materials and targeted therapies, but they typically ignore the human scientists who continually alter the landscape of…

Artificial Intelligence · Computer Science 2023-06-05 Jamshid Sourati , James Evans

While LLMs have shown impressive capabilities in solving math or coding problems, the ability to make scientific discoveries remains a distinct challenge. This paper proposes a "Turing test for an AI scientist" to assess whether an AI agent…

Artificial Intelligence · Computer Science 2024-05-24 Xiaoxin Yin

Biology is at the precipice of a new era where AI accelerates and amplifies the ability to study how cells operate, organize, and work as systems, revealing why disease happens and how to correct it. Organizations globally are prioritizing…

Modern science emerged from reasoning over repeatedly-observed planetary motions. We present Gravity-Bench-v1, an environment-based benchmark that challenges AI agents on tasks that parallel this historical development. Gravity-Bench-v1…

Artificial Intelligence · Computer Science 2025-05-30 Nolan Koblischke , Hyunseok Jang , Kristen Menou , Mohamad Ali-Dib

Open Science has been a rising theme in the landscape of science policy in recent years. The goal is to make research that emerges from publicly funded science to become findable, accessible, interoperable and reusable (FAIR) for use by…

Digital Libraries · Computer Science 2020-05-29 Julia Heuritsch

Recent years have seen tremendous growth in the amount of verified software. Proofs for complex properties can now be achieved using higher-order theories and calculi. Complex properties lead to an ever-growing number of definitions and…

Programming Languages · Computer Science 2021-11-29 Eytan Singher , Shachar Itzhaky

Drug discovery is adapting to novel technologies such as data science, informatics, and artificial intelligence (AI) to accelerate effective treatment development while reducing costs and animal experiments. AI is transforming drug…

Artificial Intelligence · Computer Science 2023-07-14 Catrin Hasselgren , Tudor I. Oprea

Infrastructure shapes societies and scientific discovery. Traditional scientific infrastructure, often static and fragmented, leads to issues like data silos, lack of interoperability and reproducibility, and unsustainable short-lived…

Neurons and Cognition · Quantitative Biology 2025-08-15 Satrajit S. Ghosh

Recent advances in large language models (LLMs) have opened new avenues for accelerating scientific research. While models are increasingly capable of assisting with routine tasks, their ability to contribute to novel, expert-level…

Many published research results are false, and controversy continues over the roles of replication and publication policy in improving the reliability of research. Addressing these problems is frustrated by the lack of a formal framework…

Other Statistics · Statistics 2015-08-27 Richard McElreath , Paul E. Smaldino

We study from the proof complexity perspective the (informal) proof search problem: Is there an optimal way to search for propositional proofs? We note that for any fixed proof system there exists a time-optimal proof search algorithm.…

Computational Complexity · Computer Science 2022-07-12 Jan Krajicek

A fundamental question in the field of social studies of science is how research fields emerge, grow and decline over time and space. This study confronts this question here by developing an inductive analysis of emerging research fields…

General Economics · Economics 2018-07-23 Mario Coccia

The number of scientific articles has grown rapidly over the years and there are no signs that this growth will slow down in the near future. Because of this, it becomes increasingly difficult to keep up with the latest developments in a…

Information Retrieval · Computer Science 2017-07-26 Tom Jansen , Tobias Kuhn

Advancements in mathematical programming have made it possible to efficiently tackle large-scale real-world problems that were deemed intractable just a few decades ago. However, provably optimal solutions may not be accepted due to the…

Optimization and Control · Mathematics 2023-12-22 Kevin-Martin Aigner , Marc Goerigk , Michael Hartisch , Frauke Liers , Arthur Miehlich
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