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Quantitative Susceptibility Mapping (QSM) dipole inversion is an ill-posed inverse problem for quantifying magnetic susceptibility distributions from MRI tissue phases. While supervised deep learning methods have shown success in specific…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Zhuang Xiong , Wei Jiang , Yang Gao , Feng Liu , Hongfu Sun

In recent years, deep learning methods have been extensively developed for inverse imaging problems (IIPs), encompassing supervised, self-supervised, and generative approaches. Most of these methods require large amounts of labeled or…

Image and Video Processing · Electrical Eng. & Systems 2025-12-04 Ismail Alkhouri , Evan Bell , Avrajit Ghosh , Shijun Liang , Rongrong Wang , Saiprasad Ravishankar

Deep image prior (DIP) is a recently proposed technique for solving imaging inverse problems by fitting the reconstructed images to the output of an untrained convolutional neural network. Unlike pretrained feedforward neural networks, the…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Kevin Zhang , Mingyang Xie , Maharshi Gor , Yi-Ting Chen , Yvonne Zhou , Christopher A. Metzler

We propose Nonlinear Dipole Inversion (NDI) for high-quality Quantitative Susceptibility Mapping (QSM) without regularization tuning, while matching the image quality of state-of-the-art reconstruction techniques. In addition to avoiding…

Image and Video Processing · Electrical Eng. & Systems 2019-10-01 Daniel Polak , Itthi Chatnuntawech , Jaeyeon Yoon , Siddharth Srinivasan Iyer , Jongho Lee , Peter Bachert , Elfar Adalsteinsson , Kawin Setsompop , Berkin Bilgic

Quantitative susceptibility mapping (QSM) is a powerful MRI technique that has shown great potential in quantifying tissue susceptibility in numerous neurological disorders. However, the intrinsic ill-posed dipole inversion problem greatly…

Image and Video Processing · Electrical Eng. & Systems 2019-10-31 Yicheng Chen , Angela Jakary , Sivakami Avadiappan , Christopher P. Hess , Janine M. Lupo

Quantitative susceptibility mapping (QSM) has demonstrated great potential in quantifying tissue susceptibility in various brain diseases. However, the intrinsic ill-posed inverse problem relating the tissue phase to the underlying…

Computer Vision and Pattern Recognition · Computer Science 2021-05-21 Ruimin Feng , Jiayi Zhao , He Wang , Baofeng Yang , Jie Feng , Yuting Shi , Ming Zhang , Chunlei Liu , Yuyao Zhang , Jie Zhuang , Hongjiang Wei

Deep neural networks have demonstrated promising potential for the field of medical image reconstruction. In this work, an MRI reconstruction algorithm, which is referred to as quantitative susceptibility mapping (QSM), has been developed…

Image and Video Processing · Electrical Eng. & Systems 2018-06-18 Jaeyeon Yoon , Enhao Gong , Itthi Chatnuntawech , Berkin Bilgic , Jingu Lee , Woojin Jung , Jingyu Ko , Hosan Jung , Kawin Setsompop , Greg Zaharchuk , Eung Yeop Kim , John Pauly , Jongho Lee

Recent advances in data-centric deep generative models have led to significant progress in solving inverse imaging problems. However, these models (e.g., diffusion models (DMs)) typically require large amounts of fully sampled (clean)…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Shijun Liang , Ismail R. Alkhouri , Siddhant Gautam , Qing Qu , Saiprasad Ravishankar

Recent inverse problem solvers that leverage generative diffusion priors have garnered significant attention due to their exceptional quality. However, adaptation of the prior is necessary when there exists a discrepancy between the…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Hyungjin Chung , Jong Chul Ye

Conventional deconvolution methods utilize hand-crafted image priors to constrain the optimization. While deep-learning-based methods have simplified the optimization by end-to-end training, they fail to generalize well to blurs unseen in…

Image and Video Processing · Electrical Eng. & Systems 2023-06-07 Dong Huo , Abbas Masoumzadeh , Rafsanjany Kushol , Yee-Hong Yang

Deep image prior (DIP) was recently introduced as an effective unsupervised approach for image restoration tasks. DIP represents the image to be recovered as the output of a deep convolutional neural network, and learns the network's…

Image and Video Processing · Electrical Eng. & Systems 2023-02-10 Riccardo Barbano , Johannes Leuschner , Maximilian Schmidt , Alexander Denker , Andreas Hauptmann , Peter Maaß , Bangti Jin

Quantitative susceptibility mapping (QSM) is an MRI phase-based post-processing technique to extract the distribution of tissue susceptibilities, demonstrating significant potential in studying neurological diseases. However, the…

Image and Video Processing · Electrical Eng. & Systems 2024-06-19 Min Li , Chen Chen , Zhuang Xiong , Ying Liu , Pengfei Rong , Shanshan Shan , Feng Liu , Hongfu Sun , Yang Gao

This paper investigates the application of unsupervised learning methods for computed tomography (CT) reconstruction. To motivate our work, we review several existing priors, namely the truncated Gaussian prior, the $l_1$ prior, the total…

Image and Video Processing · Electrical Eng. & Systems 2023-06-02 Chen Cheng , Qingping Zhou

Quantitative Susceptibility Mapping (QSM) estimates tissue magnetic susceptibility distributions from Magnetic Resonance (MR) phase measurements by solving an ill-posed dipole inversion problem. Conventional single orientation QSM methods…

Image and Video Processing · Electrical Eng. & Systems 2020-08-13 Kuo-Wei Lai , Manisha Aggarwal , Peter van Zijl , Xu Li , Jeremias Sulam

Deep neural networks have demonstrated great potential in solving dipole inversion for Quantitative Susceptibility Mapping (QSM). However, the performances of most existing deep learning methods drastically degrade with mismatched sequence…

Medical Physics · Physics 2022-11-28 Zhuang Xiong , Yang Gao , Feng Liu , Hongfu Sun

We present a comprehensive overview of the Deep Image Prior (DIP) framework and its applications to image reconstruction in computed tomography. Unlike conventional deep learning methods that rely on large, supervised datasets, the DIP…

Image and Video Processing · Electrical Eng. & Systems 2026-02-24 Simon Arridge , Riccardo Barbano , Alexander Denker , Zeljko Kereta

Quantitative susceptibility mapping (QSM) is a useful magnetic resonance imaging (MRI) technique which provides spatial distribution of magnetic susceptibility values of tissues. QSMs can be obtained by deconvolving the dipole kernel from…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Gyutaek Oh , Hyokyoung Bae , Hyun-Seo Ahn , Sung-Hong Park , Jong Chul Ye

Quantitative susceptibility mapping (QSM) estimates the underlying tissue magnetic susceptibility from MRI gradient-echo phase signal and typically requires several processing steps. These steps involve phase unwrapping, brain volume…

Image and Video Processing · Electrical Eng. & Systems 2019-05-16 Hongjiang Wei , Steven Cao , Yuyao Zhang , Xiaojun Guan , Fuhua Yan , Kristen W. Yeom , Chunlei Liu

Introduction: Quantitative Susceptibility Mapping (QSM) is generally acquired with full brain coverage, even though many QSM brain-iron studies focus on the deep grey matter (DGM) region only. Reducing the spatial coverage to the DGM…

Quantitative Methods · Quantitative Biology 2021-06-02 Xuanyu Zhu , Yang Gao , Feng Liu , Stuart Crozier , Hongfu Sun

We propose a novel method for compressed sensing recovery using untrained deep generative models. Our method is based on the recently proposed Deep Image Prior (DIP), wherein the convolutional weights of the network are optimized to match…

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