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Large language models (LLMs) have achieved remarkable progress in automatic code generation, yet their ability to produce high-performance code remains limited--a critical requirement in real-world software systems. We argue that current…

Software Engineering · Computer Science 2026-05-11 Jiuding Yang , Shengyao Lu , Hongxuan Liu , Shayan Shirahmad Gale Bagi , Zahra Fazel , Tomasz Czajkowski , Di Niu

Despite the remarkable success of large language models (LLMs) on traditional natural language processing tasks, their planning ability remains a critical bottleneck in tackling complex multi-step reasoning tasks. Existing approaches mainly…

Computation and Language · Computer Science 2024-10-07 Jiaxin Wen , Jian Guan , Hongning Wang , Wei Wu , Minlie Huang

Tool use has turned large language models (LLMs) into powerful agents that can perform complex multi-step tasks by dynamically utilising external software components. However, these tools must be implemented in advance by human developers,…

Computation and Language · Computer Science 2025-06-02 Georg Wölflein , Dyke Ferber , Daniel Truhn , Ognjen Arandjelović , Jakob Nikolas Kather

Recently, large language models (LLMs) have outperformed human experts in predicting the results of neuroscience experiments (Luo et al., 2024). What is the basis for this performance? One possibility is that statistical patterns in that…

Neurons and Cognition · Quantitative Biology 2024-07-03 Xiaoliang Luo , Guangzhi Sun , Bradley C. Love

Large language models (LLMs) can be used to support software development tasks, e.g., through code completion or code generation. However, their effectiveness drops significantly when considering less popular programming languages such as…

Software Engineering · Computer Science 2026-03-06 David Delgado , Lola Burgueño , Robert Clarisó

Recent research has explored the creation of questions from code submitted by students. These Questions about Learners' Code (QLCs) are created through program analysis, exploring execution paths, and then creating code comprehension…

Computers and Society · Computer Science 2024-04-19 Teemu Lehtinen , Charles Koutcheme , Arto Hellas

Large Language Models (LLMs) are revolutionizing Software Engineering (SE) by introducing innovative methods for tasks such as collecting requirements, designing software, generating code, and creating test cases, among others. This article…

Software Engineering · Computer Science 2024-05-06 Malik Abdul Sami , Zeeshan Rasheed , Muhammad Waseem , Zheying Zhang , Tomas Herda , Pekka Abrahamsson

Large language models have made remarkable progress in the field of molecular science, particularly in understanding and generating functional small molecules. This success is largely attributed to the effectiveness of molecular…

Biomolecules · Quantitative Biology 2025-03-14 Zicheng Ma , Chuanliu Fan , Zhicong Wang , Zhenyu Chen , Xiaohan Lin , Yanheng Li , Shihao Feng , Jun Zhang , Ziqiang Cao , Yi Qin Gao

Large Language Models (LLMs), typified by OpenAI's GPT, have marked a significant advancement in artificial intelligence. Trained on vast amounts of text data, LLMs are capable of understanding and generating human-like text across a…

Artificial Intelligence · Computer Science 2024-10-29 Haochen Zhang , Yuyang Dong , Chuan Xiao , Masafumi Oyamada

The rapid integration of Large Language Models (LLMs) into various industries presents both revolutionary opportunities and unique challenges. This research aims to establish a scalable and efficient framework for LLM customization,…

Software Engineering · Computer Science 2024-05-22 Panos Fitsilis , Vyron Damasiotis , Vasileios Kyriatzis , Paraskevi Tsoutsa

Large language models (LLMs), such as Codex and GPT-4, have recently showcased their remarkable code generation abilities, facilitating a significant boost in coding efficiency. This paper will delve into utilizing LLMs for code generation…

Software Engineering · Computer Science 2023-07-31 Daoguang Zan , Bei Chen , Yongshun Gong , Junzhi Cao , Fengji Zhang , Bingchao Wu , Bei Guan , Yilong Yin , Yongji Wang

With the rapid advancement of large language models (LLMs), extensive research has been conducted to investigate the code generation capabilities of LLMs. However, existing efforts primarily focus on general-domain tasks, leaving LLMs' code…

Software Engineering · Computer Science 2025-03-18 Dewu Zheng , Yanlin Wang , Ensheng Shi , Xilin Liu , Yuchi Ma , Hongyu Zhang , Zibin Zheng

Despite rapid advances in Large Language Models and Multimodal Large Language Models (LLMs), numerous challenges related to interpretability, scalability, resource requirements and repeatability remain, related to their application in the…

Software Engineering · Computer Science 2025-07-23 Sohaib Muhammad , Ashwati Vipin , Karan Shetti , Honey Mittal

Large language models (LLMs) excel at general programming but struggle with domain-specific software development, necessitating domain specialization methods for LLMs to learn and utilize domain knowledge and data. However, existing…

Software Engineering · Computer Science 2026-04-28 Xue Jiang , Ge Li , Jiaru Qian , Xianjie Shi , Chenjie Li , Hao Zhu , Ziyu Wang , Jielun Zhang , Zheyu Zhao , Lingwei Wu , Kechi Zhang , Jia Li , Wenpin Jiao , Zhi Jin , Yihong Dong

The rapid advancement of large language models (LLMs) has led to significant improvements in natural language processing but also poses challenges due to their high computational and energy demands. This paper introduces a series of…

Computation and Language · Computer Science 2024-06-27 Dylan Hillier , Leon Guertler , Cheston Tan , Palaash Agrawal , Chen Ruirui , Bobby Cheng

Large language models (LLMs) are a class of artificial intelligence models based on deep learning, which have great performance in various tasks, especially in natural language processing (NLP). Large language models typically consist of…

Quantitative Methods · Quantitative Biology 2025-02-04 Jiajia Liu , Mengyuan Yang , Yankai Yu , Haixia Xu , Tiangang Wang , Kang Li , Xiaobo Zhou

There is a growing need for Large Language Models (LLMs) to effectively use tools and external Application Programming Interfaces (APIs) to plan and complete tasks. As such, there is tremendous interest in methods that can acquire…

In recent years, language models (LMs), such as GPT-4, have been widely used in multiple domains, including natural language processing, visualization, and so on. However, applying them for analyzing and optimizing high-performance…

Machine Learning · Computer Science 2023-11-28 Le Chen , Pei-Hung Lin , Tristan Vanderbruggen , Chunhua Liao , Murali Emani , Bronis de Supinski

Large language models (LLMs) have made significant progress in natural language understanding and generation, driven by scalable pretraining and advanced finetuning. However, enhancing reasoning abilities in LLMs, particularly via…

Artificial Intelligence · Computer Science 2025-05-30 Huimu Yu , Xing Wu , Haotian Xu , Debing Zhang , Songlin Hu

Large Language Models (LLMs) have demonstrated remarkable generalization across diverse tasks, leading individuals to increasingly use them as personal assistants and universal computing engines. Nevertheless, a notable obstacle emerges…

Machine Learning · Computer Science 2023-09-13 Dimitris Spathis , Fahim Kawsar