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The absence of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. Although various methods of explainable artificial intelligence (XAI) have been suggested, there is a lack of literature that…

Machine Learning · Computer Science 2023-06-22 Aida Brankovic , David Cook , Jessica Rahman , Wenjie Huang , Sankalp Khanna

Artificial intelligence (AI) is increasingly permeating healthcare, from physician assistants to consumer applications. Since AI algorithm's opacity challenges human interaction, explainable AI (XAI) addresses this by providing AI…

Artificial Intelligence (AI) has made leapfrogs in development across all the industrial sectors especially when deep learning has been introduced. Deep learning helps to learn the behaviour of an entity through methods of recognising and…

Machine Learning · Computer Science 2021-04-30 Qinghao Ye , Jun Xia , Guang Yang

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

In the past few years, artificial intelligence (AI) techniques have been implemented in almost all verticals of human life. However, the results generated from the AI models often lag explainability. AI models often appear as a blackbox…

Cybersecurity vendors consistently apply AI (Artificial Intelligence) to their solutions and many cybersecurity domains can benefit from AI technology. However, black-box AI techniques present some difficulties in comprehension and adoption…

Cryptography and Security · Computer Science 2023-03-03 Carlos Mendes , Tatiane Nogueira Rios

The field of drug discovery has experienced a remarkable transformation with the advent of artificial intelligence (AI) and machine learning (ML) technologies. However, as these AI and ML models are becoming more complex, there is a growing…

Artificial intelligence (AI) has been clearly established as a technology with the potential to revolutionize fields from healthcare to finance - if developed and deployed responsibly. This is the topic of responsible AI, which emphasizes…

Artificial Intelligence · Computer Science 2023-12-05 Stephanie Baker , Wei Xiang

Given the complexity and lack of transparency in deep neural networks (DNNs), extensive efforts have been made to make these systems more interpretable or explain their behaviors in accessible terms. Unlike most reviews, which focus on…

Artificial Intelligence · Computer Science 2024-01-17 Haoyi Xiong , Xuhong Li , Xiaofei Zhang , Jiamin Chen , Xinhao Sun , Yuchen Li , Zeyi Sun , Mengnan Du

Deep neural networks have become increasingly popular for analyzing ECG data because of their ability to accurately identify cardiac conditions and hidden clinical factors. However, the lack of transparency due to the black box nature of…

Signal Processing · Electrical Eng. & Systems 2024-07-03 Patrick Wagner , Temesgen Mehari , Wilhelm Haverkamp , Nils Strodthoff

Artificial intelligence systems are widely used by people with sensory disabilities, like loss of vision or hearing, to help perceive or navigate the world around them. This includes tasks like describing an image or object they cannot…

Human-Computer Interaction · Computer Science 2026-03-04 Shadab H. Choudhury

Knee osteoarthritis (OA) is the most common joint disorder and a leading cause of disability. Diagnosing OA severity typically requires expert assessment of X-ray images and is commonly based on the Kellgren-Lawrence grading system, a…

Image and Video Processing · Electrical Eng. & Systems 2024-12-11 Nicharee Srikijkasemwat , Soumya Snigdha Kundu , Fuping Wu , Bartlomiej W. Papiez

Modern AI systems frequently rely on opaque black-box models, most notably Deep Neural Networks, whose performance stems from complex architectures with millions of learned parameters. While powerful, their complexity poses a major…

Machine Learning · Computer Science 2026-02-23 David Dembinsky , Adriano Lucieri , Stanislav Frolov , Hiba Najjar , Ko Watanabe , Andreas Dengel

Explainable AI (XAI) aims to provide interpretations for predictions made by learning machines, such as deep neural networks, in order to make the machines more transparent for the user and furthermore trustworthy also for applications in…

Machine Learning · Computer Science 2020-06-17 Kirill Bykov , Marina M. -C. Höhne , Klaus-Robert Müller , Shinichi Nakajima , Marius Kloft

The remarkable advancements in Deep Learning (DL) algorithms have fueled enthusiasm for using Artificial Intelligence (AI) technologies in almost every domain; however, the opaqueness of these algorithms put a question mark on their…

Machine Learning · Computer Science 2021-01-12 F. Hussain , R. Hussain , E. Hossain

With the advances in artificial intelligence (AI), data-driven algorithms are becoming increasingly popular in the medical domain. However, due to the nonlinear and complex behavior of many of these algorithms, decision-making by such…

Quantitative Methods · Quantitative Biology 2024-07-18 Amirehsan Ghasemi , Soheil Hashtarkhani , David L Schwartz , Arash Shaban-Nejad

Uncertainty is a fundamental challenge in medical practice, but current medical AI systems fail to explicitly quantify or communicate uncertainty in a way that aligns with clinical reasoning. Existing XAI works focus on interpreting model…

Artificial Intelligence · Computer Science 2025-09-24 Xiuyi Fan

The aim of this study was to investigate the influence of MRI and patient data on the prediction of knee osteoarthritis (OA) incidence using different deep learning architectures. Knee OA incidence within 24 months was predicted using the…

Medical Physics · Physics 2022-09-05 Anastasis Alexopoulos , Jukka Hirvasniemi , Nazli Tümer

Many ML models are opaque to humans, producing decisions too complex for humans to easily understand. In response, explainable artificial intelligence (XAI) tools that analyze the inner workings of a model have been created. Despite these…

Computers and Society · Computer Science 2021-06-17 Kiana Alikhademi , Brianna Richardson , Emma Drobina , Juan E. Gilbert

Knee osteoarthritis (OA) is the most common osteoarthritis and a leading cause of disability. Cartilage defects are regarded as major manifestations of knee OA, which are visible by magnetic resonance imaging (MRI). Thus early detection and…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Zixu Zhuang , Liping Si , Sheng Wang , Kai Xuan , Xi Ouyang , Yiqiang Zhan , Zhong Xue , Lichi Zhang , Dinggang Shen , Weiwu Yao , Qian Wang
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