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Multimodal manifold modeling methods extend the spectral geometry-aware data analysis to learning from several related and complementary modalities. Most of these methods work based on two major assumptions: 1) there are the same number of…

Machine Learning · Computer Science 2021-05-13 Maysam Behmanesh , Peyman Adibi , Jocelyn Chanussot , Sayyed Mohammad Saeed Ehsani

Both functional and structural magnetic resonance imaging (fMRI and sMRI) are widely used for the diagnosis of mental disorder. However, combining complementary information from these two modalities is challenging due to their…

Image and Video Processing · Electrical Eng. & Systems 2024-04-02 Ziyu Zhou , Anton Orlichenko , Gang Qu , Zening Fu , Vince D Calhoun , Zhengming Ding , Yu-Ping Wang

Computer-aided diagnosis (CAD) systems play a crucial role in analyzing neuroimaging data for neurological and psychiatric disorders. However, small-sample studies suffer from low reproducibility, while large-scale datasets introduce…

Machine Learning · Computer Science 2025-08-12 Xinglin Zhao , Yanwen Wang , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen

Background: Functional magnetic resonance imaging (fMRI) provides non-invasive measures of neuronal activity using an endogenous Blood Oxygenation-Level Dependent (BOLD) contrast. This article introduces a nonlinear dimensionality reduction…

Image and Video Processing · Electrical Eng. & Systems 2019-12-09 Gagan Sidhu

Resting-state functional MRI (rs-fMRI) is increasingly employed in multi-site research to aid neurological disorder analysis. Existing studies usually suffer from significant cross-site/domain data heterogeneity caused by site effects such…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yuqi Fang , Jinjian Wu , Qianqian Wang , Shijun Qiu , Andrea Bozoki , Huaicheng Yan , Mingxia Liu

Large-scale population-based studies in medicine are a key resource towards better diagnosis, monitoring, and treatment of diseases. They also serve as enablers of clinical decision support systems, in particular Computer Aided Diagnosis…

Machine Learning · Computer Science 2022-03-01 Gerome Vivar , Anees Kazi , Hendrik Burwinkel , Andreas Zwergal , Nassir Navab , Seyed-Ahmad Ahmadi

With the increasing amounts of high-dimensional heterogeneous data to be processed, multi-modality feature selection has become an important research direction in medical image analysis. Traditional methods usually depict the data structure…

Computer Vision and Pattern Recognition · Computer Science 2022-04-11 Yuang Shi , Chen Zu , Mei Hong , Luping Zhou , Lei Wang , Xi Wu , Jiliu Zhou , Daoqiang Zhang , Yan Wang

For the early identification, diagnosis, and treatment of mental health illnesses, the integration of deep learning (DL) and machine learning (ML) has started playing a significant role. By evaluating complex data from imaging, genetics,…

Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…

Neurons and Cognition · Quantitative Biology 2025-09-24 Ali Khazaee , Abdolreza Mohammadi , Ruairi O'Reilly

Long-form mental health assessments pose unique challenges for large language models (LLMs), which often exhibit hallucinations or inconsistent reasoning when handling extended, domain-specific contexts. We introduce Stacked Multi-Model…

Computation and Language · Computer Science 2025-09-22 Jinwen Tang , Qiming Guo , Wenbo Sun , Yi Shang

Substantial evidence indicates that major psychiatric disorders are associated with distributed neural dysconnectivity, leading to strong interest in using neuroimaging methods to accurately predict disorder status. In this work, we are…

Machine Learning · Statistics 2014-03-26 Takanori Watanabe , Daniel Kessler , Clayton Scott , Michael Angstadt , Chandra Sripada

Multimodal sentiment analysis and depression estimation are two important research topics that aim to predict human mental states using multimodal data. Previous research has focused on developing effective fusion strategies for exchanging…

Multimedia · Computer Science 2022-09-14 Hao Sun , Hongyi Wang , Jiaqing Liu , Yen-Wei Chen , Lanfen Lin

The current methods for diagnosing Alzheimer Disease using Magnetic Resonance Imaging (MRI) have significant limitations. Many previous studies used 2D Transformers to analyze individual brain slices independently, potentially losing…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Juan A. Castro-Silva , Maria N. Moreno Garcia , Diego H. Peluffo-Ordoñez

Preliminary detection of mild depression could immensely help in effective treatment of the common mental health disorder. Due to the lack of proper awareness and the ample mix of stigmas and misconceptions present within the society,…

Resting-state functional Magnetic Resonance Imaging (R-fMRI) holds the promise to reveal functional biomarkers of neuropsychiatric disorders. However, extracting such biomarkers is challenging for complex multi-faceted neuropatholo-gies,…

Multimodal depression detection is an important research topic that aims to predict human mental states using multimodal data. Previous methods treat different modalities equally and fuse each modality by na\"ive mathematical operations…

Computation and Language · Computer Science 2024-01-09 Yuntao Wei , Yuzhe Zhang , Shuyang Zhang , Hong Zhang

Deep learning methods are increasingly being used with neuroimaging data like structural and function magnetic resonance imaging (MRI) to predict the diagnosis of neuropsychiatric and neurological disorders. For psychiatric disorders in…

Neurons and Cognition · Quantitative Biology 2019-07-03 Ahmed El Gazzar , Leonardo Cerliani , Guido van Wingen , Rajat Mani Thomas

Accurate diagnosis of brain disorders such as Alzheimer's disease and brain tumors remains a critical challenge in medical imaging. Conventional methods based on manual MRI analysis are often inefficient and error-prone. To address this, we…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Sumshun Nahar Eity , Mahin Montasir Afif , Tanisha Fairooz , Md. Mortuza Ahmmed , Md Saef Ullah Miah

Deep learning models can enable accurate and efficient disease diagnosis, but have thus far been hampered by the data scarcity present in the medical world. Automated diagnosis studies have been constrained by underpowered single-center…

Image and Video Processing · Electrical Eng. & Systems 2022-03-04 Akis Linardos , Kaisar Kushibar , Sean Walsh , Polyxeni Gkontra , Karim Lekadir

Depression is a severe mental disorder, and reliable identification plays a critical role in early intervention and treatment. Multimodal depression detection aims to improve diagnostic performance by jointly modeling complementary…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Chongxiao Wang , Junjie Liang , Peng Cao , Jinzhu Yang , Osmar R. Zaiane