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Brain disorders are a major challenge to global health, causing millions of deaths each year. Accurate diagnosis of these diseases relies heavily on advanced medical imaging techniques such as Magnetic Resonance Imaging (MRI) and Computed…

Computer Vision and Pattern Recognition · Computer Science 2024-05-07 Xuran Zhu

We propose a matrix factorization technique that decomposes the resting state fMRI (rs-fMRI) correlation matrices for a patient population into a sparse set of representative subnetworks, as modeled by rank one outer products. The…

Signal Processing · Electrical Eng. & Systems 2018-07-26 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart Mostofsky , Archana Venkataraman

Major depressive disorder (MDD) is a common mental disorder that typically affects a person's mood, cognition, behavior, and physical health. Resting-state functional magnetic resonance imaging (rs-fMRI) data are widely used for…

Image and Video Processing · Electrical Eng. & Systems 2024-06-10 Yunling Ma , Chaojun Zhang , Xiaochuan Wang , Qianqian Wang , Liang Cao , Limei Zhang , Mingxia Liu

Brain functional connectivity (FC) extracted from resting-state fMRI (RS-fMRI) has become a popular approach for disease diagnosis, where discriminating subjects with mild cognitive impairment (MCI) from normal controls (NC) is still one of…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Weizheng Yan , Han Zhang , Jing Sui , Dinggang Shen

Background: Depression has become a major health burden worldwide, and effective detection depression is a great public-health challenge. This Electroencephalography (EEG)-based research is to explore the effective biomarkers for depression…

Signal Processing · Electrical Eng. & Systems 2020-02-26 Shuting Sun , Jianxiu Li , Huayu Chen , Tao Gong , Xiaowei Li , Bin Hu

Depression poses serious public health risks, including suicide, underscoring the urgency of timely and scalable screening. Multimodal automatic depression detection (ADD) offers a promising solution; however, widely studied audio- and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-09 Jiuyi Chen , Mingkui Tan , Haifeng Lu , Qiuna Xu , Zhihua Wang , Runhao Zeng , Xiping Hu

In recent years, there has been a notable increase in the use of supervised detection methods of major depressive disorder (MDD) based on electroencephalogram (EEG) signals. However, the process of labeling MDD remains challenging. As a…

Machine Learning · Computer Science 2025-12-17 Li-Xuan Zhao , Chen-Yang Xu , Wen-Qiang Li , Bo Wang , Rong-Xing Wei , Qing-Hao Menga

Mental disorders are among the foremost contributors to the global healthcare challenge. Research indicates that timely diagnosis and intervention are vital in treating various mental disorders. However, the early somatization symptoms of…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Yichun Li , Shuanglin Li , Syed Mohsen Naqvi

Many supervised machine learning frameworks have been proposed for disease classification using functional magnetic resonance imaging (fMRI) data, producing important biomarkers. More recently, data pooling has flourished, making the result…

Quantitative Methods · Quantitative Biology 2022-02-24 Dushyant Sahoo , Mathilde Antoniades , Cynthia H. Y. Fu , Christos Davatzikos

Emerging evidence showed that major depressive disorder (MDD) is associated with disruptions of brain structural and functional networks, rather than impairment of isolated brain region. Thus, connectome-based models capable of predicting…

Neurons and Cognition · Quantitative Biology 2021-10-18 Aya Kabbara , Gabriel Robert , Mohamad Khalil , Marc Verin , Pascal Benquet , Mahmoud Hassan

This paper presents our approach to the first Multimodal Personality-Aware Depression Detection Challenge, focusing on multimodal depression detection using machine learning and deep learning models. We explore and compare the performance…

Computation and Language · Computer Science 2025-08-29 Javier Si Zhao Hong , Timothy Zoe Delaya , Sherwyn Chan Yin Kit , Pai Chet Ng , Xiaoxiao Miao

Major Depressive Disorder (MDD) is a common worldwide mental health issue with high associated socioeconomic costs. The prediction and automatic detection of MDD can, therefore, make a huge impact on society. Speech, as a non-invasive, easy…

Accurate diagnosis of psychiatric disorders plays a critical role in improving the quality of life for patients and potentially supports the development of new treatments. Many studies have been conducted on machine learning techniques that…

Machine Learning · Statistics 2019-04-15 Takashi Matsubara , Tetsuo Tashiro , Kuniaki Uehara

Resting-state functional magnetic resonance imaging (rs-fMRI) can reflect spontaneous neural activities in brain and is widely used for brain disorder analysis.Previous studies propose to extract fMRI representations through diverse…

Quantitative Methods · Quantitative Biology 2023-06-27 Qianqian Wang , Wei Wang , Yuqi Fang , P. -T. Yap , Hongtu Zhu , Hong-Jun Li , Lishan Qiao , Mingxia Liu

We present MMDS, a system capable of recognizing medical images and patient facial details, and providing professional medical diagnoses. The system consists of two core components:The first component is the analysis of medical images and…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Yi Ren , HanZhi Zhang , Weibin Li , Jun Fu , Diandong Liu , Tianyi Zhang , Jie He , Licheng Jiao

In this study, we focus on automated approaches to detect depression from clinical interviews using multi-modal machine learning (ML). Our approach differentiates from other successful ML methods such as context-aware analysis through…

Machine Learning · Computer Science 2024-12-30 Genevieve Lam , Huang Dongyan , Weisi Lin

Major depressive disorder (MDD) presents challenges in diagnosis and treatment due to its complex and heterogeneous nature. Emerging evidence indicates that reward processing abnormalities may serve as a behavioral marker for MDD. To…

Machine Learning · Computer Science 2024-07-29 Xingche Guo , Donglin Zeng , Yuanjia Wang

Social media platforms provide valuable insights into mental health trends by capturing user-generated discussions on conditions such as depression, anxiety, and suicidal ideation. Machine learning (ML) and deep learning (DL) models have…

Computation and Language · Computer Science 2025-04-28 Zhanyi Ding , Zhongyan Wang , Yeyubei Zhang , Yuchen Cao , Yunchong Liu , Xiaorui Shen , Yexin Tian , Jianglai Dai

Background: Captured between clinical appointments using mobile devices, spoken language has potential for objective, more regular assessment of symptom severity and earlier detection of relapse in major depressive disorder. However,…

Recently, multimodal depression recognition for clinical interviews (MDRC) has recently attracted considerable attention. Existing MDRC studies mainly focus on improving task performance and have achieved significant development. However,…

Computation and Language · Computer Science 2025-01-28 Wenjie Zheng , Qiming Xie , Zengzhi Wang , Jianfei Yu , Rui Xia