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Polyhedral vesicles with a large bending modulus of the membrane such as the gel phase lipid membrane were studied using a Brownian dynamics simulation. The vesicles exhibit various polyhedral morphologies such as tetrahedron and cube…

Soft Condensed Matter · Physics 2009-11-07 Hiroshi Noguchi

Lipid membranes have complex compositions and modeling the thermodynamic properties of multi-component lipid systems remains a remote goal. In this work we attempt to describe the thermodynamics of binary lipid mixtures by mapping…

Soft Condensed Matter · Physics 2024-09-04 L. Berezovska , R. Kociurzynski , F. Thalmann

The deformation and rupture of a lipid vesicle due to the forced normal approach of an inclusion are essential for optimizing the design of magnetic giant unilamellar vesicles [magGUVs, Malik et al., Nanoscale 17, 13720 (2025)], with…

Soft Condensed Matter · Physics 2025-12-16 Yuan-Nan Young , Bryan Quaife , Herve Nganguia , On Shun Pak , Jie Feng , Howard A. Stone

The structure, thermodynamics and slow activated dynamics of the equilibrated metastable regime of glass-forming fluids remains a poorly understood problem of high theoretical and experimental interest. We apply a highly accurate…

Soft Condensed Matter · Physics 2024-08-21 Subhashish Chaki , Baicheng Mei , Kenneth S. Schweizer

We investigate the behavior of colloidal suspensions with different volume fractions confined between parallel walls under a range of steady shears. We model the particles using molecular dynamics (MD) with full hydrodynamic interactions…

Soft Condensed Matter · Physics 2014-09-18 Frances E. Mackay , Kyle Pastor , Mikko Karttunen , Colin Denniston

Flowing blood displays a phenomenon called margination, in which leukocytes and platelets are preferentially found near blood vessel walls, while erythrocytes are depleted from these regions. Here margination is investigated using direct…

Soft Condensed Matter · Physics 2012-09-05 Amit Kumar , Michael D. Graham

Cellular membranes are a heterogeneous mix of lipids, proteins and small molecules. Special groupings of saturated lipids and cholesterol form a liquid-ordered phase, known as `lipid rafts,' serving as platforms for signaling, trafficking…

Quantitative Methods · Quantitative Biology 2015-05-13 Tristan S. Ursell , William S. Klug , Rob Phillips

Through Monte Carlo simulations and the Associating Lattice Gas Model, the phases of a two-dimensional fluid under hydrophilic confinement are evaluated. The model, in its unconfined version, reproduces the anomalous behavior of water…

Lipid membranes form the barrier between the inside and outside of cells and many of their subcompartments. As such, they bind to a wide variety of nano- and micrometer sized objects and, in the presence of strong adhesive forces, strongly…

Soft Condensed Matter · Physics 2021-08-31 Hendrik T. Spanke , Jaime Agudo-Canalejo , Daniel Tran , Robert W. Style , Eric R. Dufresne

We experimentally study the dynamics of active particles (APs) in a viscoelastic fluid under various geometrical constraints such as flat walls, spherical obstacles and cylindrical cavities. We observe that the main effect of the confined…

Soft Condensed Matter · Physics 2020-07-21 N Narinder , Juan Ruben Gomez-Solano , Clemens Bechinger

We study the phase behavior of multicomponent lipid bilayer vesicles that can exhibit intriguing morphological patterns and lateral phase separation. We use a modified Landau-Ginzburg model capable of describing spatially uniform phases,…

Soft Condensed Matter · Physics 2018-06-22 Yongtian Luo , Lutz Maibaum

Fluid mixtures, such as the cellular cytoplasm and synthetic DNA nanostars, can spontaneously compartmentalize into many coexisting phases through liquid-liquid phase separation. Despite the diversity of fluid structures that emerge from…

Fluid Dynamics · Physics 2026-03-05 Michael Rennick , Xitong Zhang , Halim Kusumaatmaja

We study numerically how multiple deformable capsules squeeze into a constriction. This situation is largely encountered in microfluidic chips designed to manipulate living cells, which are soft entities. We use fully three-dimensional…

Soft Condensed Matter · Physics 2021-12-15 Clément Bielinski , Othmane Aouane , Jens Harting , Badr Kaoui

We study the linearized hydrodynamics of a two-component fluid membrane near a repulsive wall, via a model which incorporates curvature- concentration coupling as well as hydrodynamic interactions. This model is a simplified version of a…

Soft Condensed Matter · Physics 2009-11-07 Sumithra Sankararaman , Gautam I. Menon , P. B. Sunil Kumar

The viscosity of lipid bilayer membranes plays an important role in determining the diffusion constant of embedded proteins and the dynamics of membrane deformations, yet it has historically proven very difficult to measure. Here we…

Soft Condensed Matter · Physics 2013-08-30 Aurelia R. Honerkamp-Smith , Francis G. Woodhouse , Vasily Kantsler , Raymond E. Goldstein

Using molecular dynamics simulations, we study the slow dynamics of supercooled liquids confined in a random matrix of immobile obstacles. We study the dynamical crossover from glass-like to Lorentz-gas-like behavior in terms of the density…

Soft Condensed Matter · Physics 2011-05-30 Kang Kim , Kunimasa Miyazaki , Shinji Saito

We consider the hydrodynamics of lipid bilayers containing transmembrane proteins of arbitrary shape. This biologically-motivated problem is relevant to the cell membrane, whose fluctuating dynamics play a key role in phenomena ranging from…

Soft Condensed Matter · Physics 2016-10-10 Andrew Callan-Jones , Marc Durand , Jean-Baptiste Fournier

We implement molecular dynamics simulations in canonical ensemble to study the effect of confinement on a $2d$ crystal of point particles interacting with an inverse power law potential proportional to $r^{-12}$ in a narrow channel. This…

Soft Condensed Matter · Physics 2014-09-30 M. Ebrahim Foulaadvand , Neda Ojaghlou

The dynamics of an adhesive two-dimensional vesicle doublet under various flow conditions is investigated numerically using a high-order, adaptive-in-time boundary integral method. In a quiescent flow, two nearby vesicles move slowly…

Fluid Dynamics · Physics 2019-07-23 Bryan Quaife , Shravan Veerapaneni , Y. -N. Young

The adhesion dynamics of a membrane confined between two permeable walls is studied using a two-dimensional hydrodynamic model. The membrane morphology decomposes into adhesion patches on the upper and the lower walls and obeys a nonlinear…

Soft Condensed Matter · Physics 2014-09-16 Thomas Le Goff , Paolo Politi , Olivier Pierre-Louis
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