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Multisite protein phosphorylation plays a prominent role in intracellular processes like signal transduction, cell-cycle control and nuclear signal integration. Many proteins are phosphorylated in a sequential and distributive way at more…

Molecular Networks · Quantitative Biology 2014-04-24 Dietrich Flockerzi , Katharina Holstein , Carsten Conradi

Multistationarity in molecular systems underlies switch-like responses in cellular decision making. Determining whether and when a system displays multistationarity is in general a difficult problem. In this work we completely determine the…

Molecular Networks · Quantitative Biology 2020-04-15 E. Feliu , N. Kaihnsa , T. de Wolff , O. Yürük

The multiple futile cycle is a phosphorylation system in which a molecular substrate might be phosphorylated sequentially n times by means of an enzymatic mechanism. The system has been studied mathematically using reaction network theory…

Molecular Networks · Quantitative Biology 2020-10-28 Elisenda Feliu , Alan D. Rendall , Carsten Wiuf

Systems of ODEs coupled with the topology of a closed ring are common models in biology, robotics, electrical engineering, and many other areas of science. When the component systems and couplings are identical, the system has a cyclic…

Dynamical Systems · Mathematics 2024-03-26 Ian Stewart

Multisite protein phosphorylation plays a pivotal role in regulating cellular signaling and decision-making processes. In this study, we focus on the mathematical underpinnings and informational aspects of sequential, distributive…

Molecular Networks · Quantitative Biology 2025-07-22 Iman Tavassoly , Adel Mehrpooya , Parsa Mirlohi , Zahra Abbaspourasadollah

The bifurcation structure of coupled periodically driven double-well Duffing oscillators is investigated as a function of the strength of the driving force $f$ and its frequency $\Omega$. We first examine the stability of the steady state…

Chaotic Dynamics · Physics 2015-06-26 Anatole Kenfack

Autonomous sustained oscillations are ubiquitous in living and nonliving systems. As open systems, far from thermodynamic equilibrium, they defy entropic laws which mandate convergence to stationarity. We present structural conditions on…

Dynamical Systems · Mathematics 2020-01-07 Bernold Fiedler

Dynamics in delayed differential equations (DDEs) is a well studied problem mainly because DDEs arise in models in many areas of science including biology, physiology, population dynamics and engineering. The change of the nature in the…

We have found a way for penetrating the space of the dynamical systems towards systems of arbitrary dimension exhibiting the nonlinear mixing of a large number of oscillation modes through which extraordinarily complex time evolutions…

Adaptation and Self-Organizing Systems · Physics 2024-06-26 R. Herrero , J. Farjas , F. Pi , G. Orriols

We study the bifurcations and the chaotic behaviour of a periodically forced double-well Duffing oscillator coupled to a single-well Duffing oscillator. Using the amplitude and the frequency of the driving force as control parameters, we…

Chaotic Dynamics · Physics 2007-05-23 U. E. Vincent , A. Kenfack

In this paper, we analyze some local stability and local bifurcation properties of the Proportionally fair, TCP fair, and the Delay-based dual algorithms in the presence of two distinct time delays. In particular, our focus is on the…

Chaotic Dynamics · Physics 2019-06-19 Abuthahir Abuthahir , Gaurav Raina

This is a preliminary study for bifurcation in fractional order dynamical systems. Stability, persistence and hopf bifurcation are studied. Some studies are also done for functional equations.

Cellular Automata and Lattice Gases · Physics 2008-01-09 Hala El-Saka , E. Ahmed , M. I. Shehata , A. M. A. -El-Sayed

For many physical systems the transition from a stationary solution to sustained small amplitude oscillations corresponds to a Hopf bifurcation. For systems involving impacts, thresholds, switches, or other abrupt events, however, this…

Dynamical Systems · Mathematics 2019-05-07 David J. W. Simpson

This paper is devoted to the study of the stability of limit cycles of a nonlinear delay differential equation with a distributed delay. The equation arises from a model of population dynamics describing the evolution of a pluripotent stem…

Analysis of PDEs · Mathematics 2009-04-17 Mostafa Adimy , Fabien Crauste , Andrei Halanay , Mihaela Neamtu , Dumitru Opris

Dynamics in delayed differential equations (DDEs) is a well studied problem mainly because DDEs arise in models in many areas of science including biology, physiology, population dynamics and engineering. The change of nature in the…

We outline a general theory for the analysis of flow-distributed standing and travelling wave patterns in one-dimensional, open plug-flows of oscillatory chemical media. We treat both the amplitude and phase dynamics of small and…

Pattern Formation and Solitons · Physics 2009-11-10 Patrick N. McGraw , Michael Menzinger

Propagation of uncertainty in dynamical systems is a significant challenge. Here we focus on random multiscale ordinary differential equation models. In particular, we study Hopf bifurcation in the fast subsystem for random initial…

Dynamical Systems · Mathematics 2018-12-24 Christian Kuehn

In the first part of this paper, we showed that three coupled populations of identical phase oscillators give rise to heteroclinic cycles between invariant sets where populations show distinct frequencies. Here, we now give explicit…

Dynamical Systems · Mathematics 2019-08-05 Christian Bick , Alexander Lohse

We study the weakly nonlinear saturation of the flutter instability of a planar Cosserat rod in a viscous fluid driven by a terminal follower force. This instability, established in our preceding work as a Hopf bifurcation of a…

Mathematical Physics · Physics 2026-05-15 Mohamed Warda

We study the emergence of symmetric oscillatory behavior in multi-agent systems where each agent incorporates a continuous memory of its past states and past rates of change, modeled by distributed retarded and neutral delays. The…

Dynamical Systems · Mathematics 2026-04-23 Casey Crane