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The widespread digitization of patient data via electronic health records (EHRs) has created an unprecedented opportunity to use machine learning algorithms to better predict disease risk at the patient level. Although predictive models…

Electronic Health Records (EHRs) are integral for storing comprehensive patient medical records, combining structured data (e.g., medications) with detailed clinical notes (e.g., physician notes). These elements are essential for…

Computation and Language · Computer Science 2024-12-31 Yeonsu Kwon , Jiho Kim , Gyubok Lee , Seongsu Bae , Daeun Kyung , Wonchul Cha , Tom Pollard , Alistair Johnson , Edward Choi

The rapid adoption of Electronic Health Records (EHRs) has been instrumental in streamlining administrative tasks, increasing transparency, and enabling continuity of care across providers. An unintended consequence of the increased…

Computation and Language · Computer Science 2024-04-02 Griffin Adams

In the dynamic hospital setting, decision support can be a valuable tool for improving patient outcomes. Data-driven inference of future outcomes is challenging in this dynamic setting, where long sequences such as laboratory tests and…

Quantitative Methods · Quantitative Biology 2024-04-25 Alan D. Kaplan , Priyadip Ray , John D. Greene , Vincent X. Liu

Diagnosis of a clinical condition is a challenging task, which often requires significant medical investigation. Previous work related to diagnostic inferencing problems mostly consider multivariate observational data (e.g. physiological…

Computation and Language · Computer Science 2017-01-05 Aaditya Prakash , Siyuan Zhao , Sadid A. Hasan , Vivek Datla , Kathy Lee , Ashequl Qadir , Joey Liu , Oladimeji Farri

Many diagnostic errors occur because clinicians cannot easily access relevant information in patient Electronic Health Records (EHRs). In this work we propose a method to use LLMs to identify pieces of evidence in patient EHR data that…

Electronic health records (EHRs) house crucial patient data in clinical notes. As these notes grow in volume and complexity, manual extraction becomes challenging. This work introduces a natural language interface using large language…

Information Retrieval · Computer Science 2024-07-03 Ran Elgedawy , Ioana Danciu , Maria Mahbub , Sudarshan Srinivasan

To improve the reliability of Large Language Models (LLMs) in clinical applications, retrieval-augmented generation (RAG) is extensively applied to provide factual medical knowledge. However, beyond general medical knowledge from open-ended…

Computation and Language · Computer Science 2025-05-29 Justice Ou , Tinglin Huang , Yilun Zhao , Ziyang Yu , Peiqing Lu , Rex Ying

Electronic Health Records (EHRs) hold immense potential for advancing healthcare, offering rich, longitudinal data that combines structured information with valuable insights from unstructured clinical notes. However, the unstructured…

Computation and Language · Computer Science 2025-01-31 Huaiyuan Ying , Hongyi Yuan , Jinsen Lu , Zitian Qu , Yang Zhao , Zhengyun Zhao , Isaac Kohane , Tianxi Cai , Sheng Yu

Clinical notes contain a large amount of clinically valuable information that is ignored in many clinical decision support systems due to the difficulty that comes with mining that information. Recent work has found success leveraging deep…

Machine Learning · Computer Science 2019-11-13 Justin R. Lovelace , Nathan C. Hurley , Adrian D. Haimovich , Bobak J. Mortazavi

A crucial step within secondary analysis of electronic health records (EHRs) is to identify the patient cohort under investigation. While EHRs contain medical billing codes that aim to represent the conditions and treatments patients may…

Various deep learning algorithms have been developed to analyze different types of clinical data including clinical text classification and extracting information from 'free text' and so on. However, automate the keyword extraction from the…

Computation and Language · Computer Science 2019-10-25 Matthew Tang , Priyanka Gandhi , Md Ahsanul Kabir , Christopher Zou , Jordyn Blakey , Xiao Luo

Electronic Health Records (EHR) data analysis plays a crucial role in healthcare system quality. Because of its highly complex underlying causality and limited observable nature, causal inference on EHR is quite challenging. Deep Learning…

Machine Learning · Computer Science 2022-10-28 Jia Li , Haoyu Yang , Xiaowei Jia , Vipin Kumar , Michael Steinbach , Gyorgy Simon

The development of electronic health records (EHR) systems has enabled the collection of a vast amount of digitized patient data. However, utilizing EHR data for predictive modeling presents several challenges due to its unique…

Machine Learning · Computer Science 2024-08-14 Jiaqi Wang , Junyu Luo , Muchao Ye , Xiaochen Wang , Yuan Zhong , Aofei Chang , Guanjie Huang , Ziyi Yin , Cao Xiao , Jimeng Sun , Fenglong Ma

Electronic health records (EHR) contain large volumes of unstructured text, requiring the application of Information Extraction (IE) technologies to enable clinical analysis. We present the open-source Medical Concept Annotation Toolkit…

Recently, there is great interest to investigate the application of deep learning models for the prediction of clinical events using electronic health records (EHR) data. In EHR data, a patient's history is often represented as a sequence…

Machine Learning · Computer Science 2021-10-05 Laila Rasmy , Jie Zhu , Zhiheng Li , Xin Hao , Hong Thoai Tran , Yujia Zhou , Firat Tiryaki , Yang Xiang , Hua Xu , Degui Zhi

Modern electronic health records (EHRs) provide data to answer clinically meaningful questions. The growing data in EHRs makes healthcare ripe for the use of machine learning. However, learning in a clinical setting presents unique…

Machine Learning · Computer Science 2019-12-09 Marzyeh Ghassemi , Tristan Naumann , Peter Schulam , Andrew L. Beam , Irene Y. Chen , Rajesh Ranganath

Electronic Health Records (EHRs) provide rich longitudinal clinical evidence that is central to medical decision-making, motivating the use of retrieval-augmented generation (RAG) to ground large language model (LLM) predictions. However,…

Artificial Intelligence · Computer Science 2026-01-30 Lang Cao , Qingyu Chen , Yue Guo

Augmentation of disease diagnosis and decision-making in healthcare with machine learning algorithms is gaining much impetus in recent years. In particular, in the current epidemiological situation caused by COVID-19 pandemic, swift and…

Computers and Society · Computer Science 2021-02-23 Leopold Franz , Yash Raj Shrestha , Bibek Paudel

Applying methods in natural language processing on electronic health records (EHR) data is a growing field. Existing corpus and annotation focus on modeling textual features and relation prediction. However, there is a paucity of annotated…

Computation and Language · Computer Science 2022-04-08 Yanjun Gao , Dmitriy Dligach , Timothy Miller , Samuel Tesch , Ryan Laffin , Matthew M. Churpek , Majid Afshar
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