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Two-sample network hypothesis testing is an important inference task with applications across diverse fields such as medicine, neuroscience, and sociology. Many of these testing methodologies operate under the implicit assumption that the…

Methodology · Statistics 2024-05-28 Ayushi Saxena , Vince Lyzinski

While Large Language Models (LLMs) have emerged as powerful foundational models to solve a variety of tasks, they have also been shown to be prone to hallucinations, i.e., generating responses that sound confident but are actually incorrect…

Computation and Language · Computer Science 2026-04-29 Jiawei Li , Akshayaa Magesh , Venugopal V. Veeravalli

In this work, we propose new matrix- and tensor-based methodologies for estimating multivariate intensity functions of inhomogeneous point processes. By viewing multivariate intensity functions as infinite-dimensional matrices or tensors…

Visual grounding (VG) is the capability to identify the specific regions in an image associated with a particular text description. In medical imaging, VG enhances interpretability by highlighting relevant pathological features…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Ta Duc Huy , Duy Anh Huynh , Yutong Xie , Yuankai Qi , Qi Chen , Phi Le Nguyen , Sen Kim Tran , Son Lam Phung , Anton van den Hengel , Zhibin Liao , Minh-Son To , Johan W. Verjans , Vu Minh Hieu Phan

In-vivo examination of the physical connectivity of axonal projections through the white matter of the human brain is made possible by diffusion weighted magnetic resonance imaging (dMRI) Analysis of dMRI commonly considers derived scalar…

Image and Video Processing · Electrical Eng. & Systems 2019-12-03 Haraldur T. Hallgrimsson , Richika Sharan , Scott T. Grafton , Ambuj K. Singh

Large language models(LLMs) excel at text generation and knowledge question-answering tasks, but they are prone to generating hallucinated content, severely limiting their application in high-risk domains. Current hallucination detection…

Computation and Language · Computer Science 2025-12-25 Shize Liang , Hongzhi Wang

Brain pathologies often manifest as partial or complete loss of tissue. The goal of many neuroimaging studies is to capture the location and amount of tissue changes with respect to a clinical variable of interest, such as disease…

Computer Vision and Pattern Recognition · Computer Science 2022-08-12 Samuel Gerber , Marc Niethammer , Ebrahim Ebrahim , Joseph Piven , Stephen R. Dager , Martin Styner , Stephen Aylward , Andinet Enquobahrie

Simultaneous segmentation of multiple organs from different medical imaging modalities is a crucial task as it can be utilized for computer-aided diagnosis, computer-assisted surgery, and therapy planning. Thanks to the recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2021-09-16 Saeid Asgari Taghanaki , Yefeng Zheng , S. Kevin Zhou , Bogdan Georgescu , Puneet Sharma , Daguang Xu , Dorin Comaniciu , Ghassan Hamarneh

The increasing global prevalence of mental disorders, such as depression and PTSD, requires objective and scalable diagnostic tools. Traditional clinical assessments often face limitations in accessibility, objectivity, and consistency.…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-03 Abdelrahaman A. Hassan , Abdelrahman A. Ali , Aya E. Fouda , Radwa J. Hanafy , Mohammed E. Fouda

Missing data is a common issue in many biomedical studies. Under a paired design, some subjects may have missing values in either one or both of the conditions due to loss of follow-up, insufficient biological samples, etc. Such partially…

Since machine learning models have been applied to neuroimaging data, researchers have drawn conclusions from the derived weight maps. In particular, weight maps of classifiers between two conditions are often described as a proxy for the…

Machine Learning · Statistics 2018-08-10 Jessica Schrouff , Janaina Mourao-Miranda

Identifying, measuring and reporting lesions accurately and comprehensively from patient CT scans are important yet time-consuming procedures for physicians. Computer-aided lesion/significant-findings detection techniques are at the core of…

Computer Vision and Pattern Recognition · Computer Science 2020-09-01 Jinzheng Cai , Ke Yan , Chi-Tung Cheng , Jing Xiao , Chien-Hung Liao , Le Lu , Adam P. Harrison

Shapley values have been used extensively in machine learning, not only to explain black box machine learning models, but among other tasks, also to conduct model debugging, sensitivity and fairness analyses and to select important features…

Machine Learning · Computer Science 2024-11-22 Iqbal Madakkatel , Elina Hyppönen

Brain lesion and anatomy segmentation in magnetic resonance images are fundamental tasks in neuroimaging research and clinical practice. Given enough training data, convolutional neuronal networks (CNN) proved to outperform all existent…

Computer Vision and Pattern Recognition · Computer Science 2019-04-16 Nicolas Roulet , Diego Fernandez Slezak , Enzo Ferrante

We consider linear regression in the high-dimensional regime where the number of observations $n$ is smaller than the number of parameters $p$. A very successful approach in this setting uses $\ell_1$-penalized least squares (a.k.a. the…

Methodology · Statistics 2014-02-05 Adel Javanmard , Andrea Montanari

Suppose an $n \times d$ design matrix in a linear regression problem is given, but the response for each point is hidden unless explicitly requested. The goal is to sample only a small number $k \ll n$ of the responses, and then produce a…

Machine Learning · Computer Science 2018-09-06 Michał Dereziński , Manfred K. Warmuth , Daniel Hsu

Voxel-based Morphometry (VBM) has emerged as a powerful approach in neuroimaging research, utilized in over 7,000 studies since the year 2000. Using Magnetic Resonance Imaging (MRI) data, VBM assesses variations in the local density of…

Statistical analysis of magnetic resonance imaging (MRI) can help radiologists to detect pathologies that are otherwise likely to be missed. Deep learning (DL) has shown promise in modeling complex spatial data for brain anomaly detection.…

Computer Vision and Pattern Recognition · Computer Science 2020-11-26 Victor Saase , Holger Wenz , Thomas Ganslandt , Christoph Groden , Máté E. Maros

This paper explores the application of a simple weighted loss function to Transformer-based models for multi-label emotion detection in SemEval-2025 Shared Task 11. Our approach addresses data imbalance by dynamically adjusting class…

Computation and Language · Computer Science 2026-02-05 Xia Cui

The popularity of penalized regression in high-dimensional data analysis has led to a demand for new inferential tools for these models. False discovery rate control is widely used in high-dimensional hypothesis testing, but has only…

Methodology · Statistics 2019-01-24 Ryan Miller , Patrick Breheny