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Molecular dynamics (MD) provides insights into atomic-scale processes by integrating over time the equations that describe the motion of atoms under the action of interatomic forces. Machine learning models have substantially accelerated MD…

Chemical Physics · Physics 2026-01-26 Filippo Bigi , Sanggyu Chong , Agustinus Kristiadi , Michele Ceriotti

Using a molecular dynamics computer simulation we determine the temperature dependence of the partial structure factors for a binary Lennard-Jones system. These structure factors are used as input data to solve numerically the wave-vector…

Condensed Matter · Physics 2016-08-31 Markus Nauroth , Walter Kob

An extended first-principles molecular dynamics (FPMD) method based on Kohn-Sham scheme is proposed to elevate the temperature limit of the FPMD method in the calculation of dense plasmas. The extended method treats the wave functions of…

Plasma Physics · Physics 2016-09-08 Shen Zhang , Hongwei Wang , Wei Kang , Ping Zhang , Xian-Tu He

Molecular design requires systematic and broadly applicable methods to extract structure-property relationships. The focus of this study is on learning thermodynamic properties from molecular-liquid simulations. The methodology relies on an…

Materials Science · Physics 2023-07-04 Bernadette Mohr , Diego van der Mast , Tristan Bereau

Here we first develop the thermodynamics of microcanonical phase transitions of first and second order in systems which are thermodynamically stable in the sense of van Hove. We show how both kinds of phase transitions can unambiguously be…

Condensed Matter · Physics 2019-08-17 D. H. E. Gross , M. E. Madjet , O. Schapiro

We present a rigorous derivation for off-lattice implementations of the so-called "random-walk" algorithm recently introduced by Wang and Landau [PRL 86, 2050 (2001)]. Originally developed for discrete systems, the algorithm samples…

Statistical Mechanics · Physics 2009-11-07 M. S. Shell , P. G. Debenedetti , A. Z. Panagiotopoulos

In this paper, we suppose a possible extension of Gibbs ensemble theory so that it can provide a reasonable description to phase transitions and spontaneous symmetry breaking. The extension is founded on three hypotheses, and can be…

Statistical Mechanics · Physics 2008-11-26 Ming-wen Xiao

Constant potential method molecular dynamics simulation (CPM MD) enables the accurate modelling of atomistic electrode charges when studying the electrode-electrolyte interface at the nanoscale. Here we extend the theoretical framework of…

Materials Science · Physics 2023-05-26 Shern Ren Tee , Debra J. Searles

We review a selection of methods for performing enhanced sampling in molecular dynamics simulations. We consider methods based on collective variable biasing and on tempering, and offer both historical and contemporary perspectives. In…

Statistical Mechanics · Physics 2014-01-03 Cameron Abrams , Giovanni Bussi

Boltzmann's microcanonical entropy is the link between statistical physics and thermodynamics, forasmuch as the behavior of any thermodynamic quantity is directly related to the number of microscopic configurations. Accordingly, in this…

Statistical Mechanics · Physics 2022-11-24 L. S. Ferreira , L. N. Jorge , C. J. DaSilva , A. A. Caparica

The study of phenomena such as protein folding and conformational changes in molecules is a central theme in chemical physics. Molecular dynamics (MD) simulation is the primary tool for the study of transition processes in biomolecules, but…

Computational Physics · Physics 2022-12-14 Luke Evans , Maria K. Cameron , Pratyush Tiwary

We have investigated thermodynamic and dynamic properties as well as the dielectric constant of water-metha\-nol model mixtures in the entire range of composition by using constant pressure molecular dynamics simulations at ambient…

Soft Condensed Matter · Physics 2015-12-25 E. Galicia-Andrés , H. Dominguez , L. Pusztai , O. Pizio

Constant-potential molecular dynamics (MD) simulations are indispensable for understanding the capacitance, structure, and dynamics of electrical double layers (EDLs) at the atomistic level. However, the classical constant-potential method,…

Liquid ammonia combustion can be enhanced by co-firing with small molecular fuels such as methane, and liquid ammonia will undergo flash evaporation due to its relatively low saturation pressure. These characteristics, involving the…

Fluid Dynamics · Physics 2024-09-23 Zhenhua An , Jiangkuan Xing , Abhishek Lakshman Pillai , Ryoichi Kurose

We present an application of our new theoretical formulation of quantum dynamics, moment propagation theory (MPT) (Boyer et al., J. Chem. Phys. 160, 064113 (2024)), for employing machine-learning techniques to simulate the quantum dynamics…

Chemical Physics · Physics 2024-12-09 Nicholas J. Boyer , Christopher Shepard , Ruiyi Zhou , Jianhang Xu , Yosuke Kanai

The molecular-to-atomic liquid-liquid transition (LLT) in high-pressure hydrogen is a fundamental topic touching domains from planetary science to materials modeling. Yet, the nature of the LLT is still under debate. To resolve it,…

Disordered Systems and Neural Networks · Physics 2025-11-18 Giacomo Tenti , Bastian Jäckl , Kousuke Nakano , Matthias Rupp , Michele Casula

The physical behavior of glass-forming liquids presents complex features of both dynamic and thermodynamic nature. Some studies indicate the presence of thermodynamic anomalies and of crossovers in the dynamic properties, but their origin…

Statistical Mechanics · Physics 2018-06-08 Daniele Coslovich , Misaki Ozawa , Walter Kob

Obtaining the exciton dynamics of large photosynthetic complexes by using mixed quantum mechanics/molecular mechanics (QM/MM) is computationally demanding. We propose a machine learning technique, multi-layer perceptrons, as a tool to…

Chemical Physics · Physics 2016-06-01 Florian Häse , Stéphanie Valleau , Edward Pyzer-Knapp , Alán Aspuru-Guzik

Microcanonical thermodynamics (MCTh) is contrasted to canonical thermodynamics (CTh). At phase transitions of 1.order the two ensembles are NOT equivalent even in the thermodynamic limit . Energy fluctuations do not vanish and phase…

Statistical Mechanics · Physics 2007-05-23 D. H. E. Gross

We show direct formal relationship between the Wang-Landau iteration [PRL 86, 2050 (2001)], metadynamics [PNAS 99, 12562 (2002)] and statistical temperature molecular dynamics [PRL 97, 050601 (2006)], the major Monte Carlo and molecular…

Statistical Mechanics · Physics 2021-05-13 Christoph Junghans , Danny Perez , Thomas Vogel