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Purpose: To develop an accelerated Cartesian MRF implementation using a multi-shot EPI sequence for rapid simultaneous quantification of T1 and T2 parameters. Methods: The proposed Cartesian MRF method involved the acquisition of highly…

We introduce wave encoded acquisition and reconstruction techniques for highly accelerated echo planar imaging (EPI) with reduced g-factor penalty and image artifacts. Wave-EPI involves playing sinusoidal gradients during the EPI readout…

Image and Video Processing · Electrical Eng. & Systems 2021-06-04 Jaejin Cho , Congyu Liao , Qiyuan Tian , Zijing Zhang , Jinmin Xu , Wei-Ching Lo , Benedikt A. Poser , V. Andrew Stenger , Jason Stockmann , Kawin Setsompop , Berkin Bilgic

Purpose: Echo-planar imaging (EPI) with blip-up/down acquisition (BUDA) can provide high-quality images with minimal distortions by using two readout trains with opposing phase-encoding gradients. Because of the need for two separate…

Medical Physics · Physics 2023-08-15 Kaibao Sun , Zhifeng Chen , Guangyu Dan , Qingfei Luo , Lirong Yan , Feng Liu , Xiaohong Joe Zhou

Purpose: T2* quantification from gradient echo magnetic resonance imaging is particularly affected by subject motion due to the high sensitivity to magnetic field inhomogeneities, which are influenced by motion and might cause signal loss.…

Image and Video Processing · Electrical Eng. & Systems 2025-09-11 Hannah Eichhorn , Veronika Spieker , Kerstin Hammernik , Elisa Saks , Lina Felsner , Kilian Weiss , Christine Preibisch , Julia A. Schnabel

Modern MRI relies on the well-established Echo-Planar-Imaging (EPI) method for fast acquisition. EPI is the workhorse of diffusion and functional MRI in neuroscience as well as of many dynamic applications for clinical body imaging. Its…

Purpose: Develop a processing scheme for Gradient Echo (GRE) phase to enable restoration of susceptibility-related (SuR) features in regions affected by imperfect phase unwrapping, background suppression and low signal-to-noise ratio (SNR)…

Medical Physics · Physics 2021-06-30 Joseph Suresh Paul , Sreekanth Madhusoodhanan

BACKGROUND: Functional Magnetic Resonance Imaging (fMRI) is based on the Blood Oxygenation Level Dependent contrast and has been exploited for the indirect study of the neuronal activity within both the brain and the spinal cord. However,…

The main purpose of this study is to show that a highly accelerated Cartesian MRF scheme using a multi-shot EPI readout (i.e. multi-shot EPI-MRF) can produce good quality multi-parametric maps such as T1, T2 and proton density (PD) in a…

PURPOSE To develop free-running multi-echo GRE for cardiac- and respiratory-motion-resolved whole-heart fat fraction quantification. METHODS Multi-echo readouts optimized for water-fat separation and quantification were integrated within a…

Multicomponent T2-mapping using a gradient and spin-echo (GraSE) acquisition has become standard for myelin water imaging at 3T. Higher magnetic field strengths promise SNR benefits but face specific absorption rate limits and shortened T2…

Medical Physics · Physics 2021-05-14 Vanessa Wiggermann , Alex MacKay , Alexander Rauscher , Gunther Helms

Quantitative imaging in MRI usually involves acquisition and reconstruction of a series of images at multi-echo time points, which possibly requires more scan time and specific reconstruction technique compared to conventional qualitative…

Signal Processing · Electrical Eng. & Systems 2021-03-11 Jinwei Zhang , Hang Zhang , Chao Li , Pascal Spincemaille , Mert Sabuncu , Thanh D. Nguyen , Yi Wang

Purpose: To develop a 3D distortion-free reduced-FOV diffusion-prepared GRE sequence and demonstrate its in-vivo application for diffusion imaging of the spinal cord in healthy volunteers. Methods: A 3D multi-shot reduced-FOV…

Purpose: This work aims to develop a novel distortion-free 3D-EPI acquisition and image reconstruction technique for fast and robust, high-resolution, whole-brain imaging as well as quantitative T2* mapping. Methods: 3D-Blip-Up and -Down…

Image and Video Processing · Electrical Eng. & Systems 2022-12-02 Zhifeng Chen , Congyu Liao , Xiaozhi Cao , Benedikt A. Poser , Zhongbiao Xu , Wei-Ching Lo , Manyi Wen , Jaejin Cho , Qiyuan Tian , Yaohui Wang , Yanqiu Feng , Ling Xia , Wufan Chen , Feng Liu , Berkin Bilgic

Multi-shot echo planar imaging (msEPI) is a promising approach to achieve high in-plane resolution with high sampling efficiency and low T2* blurring. However, due to the geometric distortion, shot-to-shot phase variations and potential…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Congyu Liao , Xiaozhi Cao , Jaejin Cho , Zijing Zhang , Kawin Setsompop , Berkin Bilgic

Purpose: To develop new encoding and reconstruction techniques for fast multi-contrast quantitative imaging. Methods: The recently proposed Echo Planar Time-resolved Imaging (EPTI) technique can achieve fast distortion- and blurring-free…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Zijing Dong , Fuyixue Wang , Timothy G. Reese , Berkin Bilgic , Kawin Setsompop

Magnetic resonance imaging (MRI) based electrical properties tomography (EPT) is the quantification of the conductivity and permittivity of different tissues. These electrical properties can be obtained through different reconstruction…

PURPOSE: To correct line-to-line delays and phase errors in echo-planar imaging (EPI). THEORY AND METHODS: EPI- trajectory auto-corrected image reconstruction (EPI-TrACR) is an iterative maximum-likelihood technique that exploits data…

Medical Physics · Physics 2017-06-27 Julianna D. Ianni , E. Brian Welch , William A. Grissom

Purpose: To rapidly obtain high isotropic-resolution T2 maps with whole-brain coverage and high geometric fidelity. Methods: A T2 blip-up/down echo planar imaging (EPI) acquisition with generalized Slice-dithered enhanced resolution…

The Egger intercept (EI) test is a widely used tool to detect horizontal pleiotropy in two-sample summary-data Mendelian randomization. A significant EI test suggests that either the average pleiotropic effect differs from zero (i.e.,…

Methodology · Statistics 2026-05-28 Yilei Ma , Youpeng Su , Xin Liu , Xuanye Cui , Ping Yin , Peng Wang

Diffusion MRI is commonly performed using echo-planar imaging (EPI) due to its rapid acquisition time. However, the resolution of diffusion-weighted images is often limited by magnetic field inhomogeneity-related artifacts and blurring…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Jaejin Cho , Yohan Jun , Xiaoqing Wang , Caique Kobayashi , Berkin Bilgic
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