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The rapid growth of biomedical knowledge has outpaced our ability to efficiently extract insights and generate novel hypotheses. Large language models (LLMs) have emerged as a promising tool to revolutionize knowledge interaction and…

Computation and Language · Computer Science 2024-07-16 Biqing Qi , Kaiyan Zhang , Kai Tian , Haoxiang Li , Zhang-Ren Chen , Sihang Zeng , Ermo Hua , Hu Jinfang , Bowen Zhou

The advent of Large Language Models (LLMs) has drastically enhanced dialogue systems. However, comprehensively evaluating the dialogue abilities of LLMs remains a challenge. Previous benchmarks have primarily focused on single-turn…

Computation and Language · Computer Science 2024-11-06 Ge Bai , Jie Liu , Xingyuan Bu , Yancheng He , Jiaheng Liu , Zhanhui Zhou , Zhuoran Lin , Wenbo Su , Tiezheng Ge , Bo Zheng , Wanli Ouyang

Evaluating the quality of open-domain chatbots has become increasingly reliant on LLMs acting as automatic judges. However, existing meta-evaluation benchmarks are static, outdated, and lacking in multilingual coverage, limiting their…

Computation and Language · Computer Science 2026-01-23 John Mendonça , Alon Lavie , Isabel Trancoso

As Large Language Models (LLMs) are increasingly integrated into healthcare to address complex inquiries, ensuring their reliability remains a critical challenge. Recent studies have highlighted that generic LLMs often struggle in clinical…

Computation and Language · Computer Science 2026-04-01 Bian Sun , Zhenjian Wang , Orvill de la Torre , Zirui Wang

Large language models (LLMs) such as ChatGPT can produce coherent, cohesive, relevant, and fluent answers for various natural language processing (NLP) tasks. Taking document-level machine translation (MT) as a testbed, this paper provides…

Computation and Language · Computer Science 2023-10-25 Longyue Wang , Chenyang Lyu , Tianbo Ji , Zhirui Zhang , Dian Yu , Shuming Shi , Zhaopeng Tu

Objective: Large language models (LLMs) are attracting increasing interest in healthcare. This commentary evaluates the potential of LLMs to improve clinical prediction models (CPMs) for diagnostic and prognostic tasks, with a focus on…

Computers and Society · Computer Science 2025-11-07 Yusuf Yildiz , Goran Nenadic , Meghna Jani , David A. Jenkins

Large Language Models (LLMs) such as ChatGPT, have gained significant attention due to their impressive natural language processing capabilities. It is crucial to prioritize human-centered principles when utilizing these models.…

Computation and Language · Computer Science 2023-06-21 Yue Huang , Qihui Zhang , Philip S. Y , Lichao Sun

Large Language Models (LLMs) have emerged as influential instruments within the realm of natural language processing; nevertheless, their capacity to handle multi-party conversations (MPCs) -- a scenario marked by the presence of multiple…

Computation and Language · Computer Science 2023-10-26 Chao-Hong Tan , Jia-Chen Gu , Zhen-Hua Ling

There is a significant gap between patient needs and available mental health support today. In this paper, we aim to thoroughly examine the potential of using Large Language Models (LLMs) to assist professional psychotherapy. To this end,…

Computation and Language · Computer Science 2025-01-28 Mian Zhang , Xianjun Yang , Xinlu Zhang , Travis Labrum , Jamie C. Chiu , Shaun M. Eack , Fei Fang , William Yang Wang , Zhiyu Zoey Chen

Large Language Models (LLMs) evaluation is a patchy and inconsistent landscape, and it is becoming clear that the quality of automatic evaluation metrics is not keeping up with the pace of development of generative models. We aim to improve…

Computation and Language · Computer Science 2023-10-24 Andrea Sottana , Bin Liang , Kai Zou , Zheng Yuan

Clinical calculators are widely used, and large language models (LLMs) make it possible to engage them using natural language. We demonstrate a purpose-built chatbot that leverages software implementations of verifiable clinical calculators…

Quantitative Methods · Quantitative Biology 2025-03-25 Niranjan Kumar , Farid Seifi , Marisa Conte , Allen Flynn

Large language models (LLMs) like ChatGPT are increasingly used in academic writing, yet issues such as incorrect or fabricated references raise ethical concerns. Moreover, current content quality evaluations often rely on subjective human…

Computation and Language · Computer Science 2025-09-15 Jing Ren , Weiqi Wang

Systematic reviews are crucial for synthesizing scientific evidence but remain labor-intensive, especially when extracting detailed methodological information. Large language models (LLMs) offer potential for automating methodological…

Computation and Language · Computer Science 2025-10-14 Wenqing Zhang , Trang Nguyen , Elizabeth A. Stuart , Yiqun T. Chen

Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

Computation and Language · Computer Science 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace

The integration of Artificial Intelligence (AI), especially Large Language Models (LLMs), into the clinical diagnosis process offers significant potential to improve the efficiency and accessibility of medical care. While LLMs have shown…

Computation and Language · Computer Science 2024-10-15 Mingyu Derek Ma , Chenchen Ye , Yu Yan , Xiaoxuan Wang , Peipei Ping , Timothy S Chang , Wei Wang

Large Language Models (LLMs) have made significant strides in natural language generation but often face challenges in tasks requiring precise calculations and structural analysis. This paper investigates the performance of state-of-the-art…

Computation and Language · Computer Science 2025-02-18 Birger Moell , Johan Boye

Large Language Models (LLMs) have brought huge improvements to Artificial Intelligence (AI), which can be applied to general-purpose tasks. However, their application to textual or spoken medical consultations is still an open research…

Artificial Intelligence · Computer Science 2026-05-27 Heriberto Cuayahuitl , Grace Jang

The performance of conversational Large Language Models (LLMs) in general, and of ChatGPT in particular, is currently being evaluated on many different tasks, from logical reasoning or maths to answering questions on a myriad of topics.…

Computation and Language · Computer Science 2024-10-22 Gonzalo Martínez , José Alberto Hernández , Javier Conde , Pedro Reviriego , Elena Merino

Recent advancements in large language models (LLMs) have shown promise in generating psychotherapeutic dialogues, particularly in the context of motivational interviewing (MI). However, the inherent lack of transparency in LLM outputs…

Computation and Language · Computer Science 2024-12-18 Xin Sun , Xiao Tang , Abdallah El Ali , Zhuying Li , Pengjie Ren , Jan de Wit , Jiahuan Pei , Jos A. Bosch

There is much excitement about the opportunity to harness the power of large language models (LLMs) when building problem-solving assistants. However, the standard methodology of evaluating LLMs relies on static pairs of inputs and outputs,…

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