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Deep Learning (DL) models tend to perform poorly when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection helps to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Daria Frolova , Anton Vasiliuk , Mikhail Belyaev , Boris Shirokikh

Deep Learning models perform unreliably when the data comes from a distribution different from the training one. In critical applications such as medical imaging, out-of-distribution (OOD) detection methods help to identify such data…

Image and Video Processing · Electrical Eng. & Systems 2023-06-26 Anton Vasiliuk , Daria Frolova , Mikhail Belyaev , Boris Shirokikh

Computer-aided diagnostics has benefited from the development of deep learning-based computer vision techniques in these years. Traditional supervised deep learning methods assume that the test sample is drawn from the identical…

Computer Vision and Pattern Recognition · Computer Science 2024-07-04 Zesheng Hong , Yubiao Yue , Yubin Chen , Lele Cong , Huanjie Lin , Yuanmei Luo , Mini Han Wang , Weidong Wang , Jialong Xu , Xiaoqi Yang , Hechang Chen , Zhenzhang Li , Sihong Xie

Out-of-distribution (OOD) detection is crucial for the safety and reliability of artificial intelligence algorithms, especially in the medical domain. In the context of the Medical OOD (MOOD) detection challenge 2023, we propose a pipeline…

Computer Vision and Pattern Recognition · Computer Science 2023-10-16 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

In medical imaging, unsupervised out-of-distribution (OOD) detection offers an attractive approach for identifying pathological cases with extremely low incidence rates. In contrast to supervised methods, OOD-based approaches function…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Lemar Abdi , Francisco Caetano , Amaan Valiuddin , Christiaan Viviers , Hamdi Joudeh , Fons van der Sommen

Recent advances in deep learning have led to breakthroughs in the development of automated skin disease classification. As we observe an increasing interest in these models in the dermatology space, it is crucial to address aspects such as…

Computer Vision and Pattern Recognition · Computer Science 2021-06-03 Hannah Kim , Girmaw Abebe Tadesse , Celia Cintas , Skyler Speakman , Kush Varshney

Image classification models deployed in the real world may receive inputs outside the intended data distribution. For critical applications such as clinical decision making, it is important that a model can detect such out-of-distribution…

Computer Vision and Pattern Recognition · Computer Science 2021-07-07 Christoph Berger , Magdalini Paschali , Ben Glocker , Konstantinos Kamnitsas

Out-of-distribution (OOD) detection is crucial for safely deploying automated medical image analysis systems, as abnormal patterns in images could hamper their performance. However, OOD detection in medical imaging remains an open…

Image and Video Processing · Electrical Eng. & Systems 2025-09-18 Evi M. C. Huijben , Sina Amirrajab , Josien P. W. Pluim

Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Benjamin Lambert , Florence Forbes , Senan Doyle , Alan Tucholka , Michel Dojat

Motivation: Deep learning models deployed for use on medical tasks can be equipped with Out-of-Distribution Detection (OoDD) methods in order to avoid erroneous predictions. However it is unclear which OoDD method should be used in…

Machine Learning · Computer Science 2020-08-06 Tianshi Cao , Chin-Wei Huang , David Yu-Tung Hui , Joseph Paul Cohen

The detection and localization of anomalies is one important medical image analysis task. Most commonly, Computer Vision anomaly detection approaches rely on manual annotations that are both time consuming and expensive to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Sergio Naval Marimont , Giacomo Tarroni

Out-of-Distribution (OoD) detection aims to justify whether a given sample is from the training distribution of the classifier-under-protection, i.e., In-Distribution (InD), or from OoD. Diffusion Models (DMs) are recently utilized in OoD…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Kun Fang , Qinghua Tao , Zuopeng Yang , Xiaolin Huang , Jie Yang

Out-of-distribution (OOD) detection is a critical task for ensuring the reliability and safety of deep neural networks in real-world scenarios. Different from most previous OOD detection methods that focus on designing OOD scores or…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Yao Zhu , YueFeng Chen , Chuanlong Xie , Xiaodan Li , Rong Zhang , Hui Xue , Xiang Tian , bolun zheng , Yaowu Chen

Detection of Out-of-Distribution (OOD) samples in real time is a crucial safety check for deployment of machine learning models in the medical field. Despite a growing number of uncertainty quantification techniques, there is a lack of…

Machine Learning · Computer Science 2022-05-09 Karina Zadorozhny , Patrick Thoral , Paul Elbers , Giovanni Cinà

In a clinical setting it is essential that deployed image processing systems are robust to the full range of inputs they might encounter and, in particular, do not make confidently wrong predictions. The most popular approach to safe…

Methods for out-of-distribution (OOD) detection that scale to 3D data are crucial components of any real-world clinical deep learning system. Classic denoising diffusion probabilistic models (DDPMs) have been recently proposed as a robust…

Density-based Out-of-distribution (OOD) detection has recently been shown unreliable for the task of detecting OOD images. Various density ratio based approaches achieve good empirical performance, however methods typically lack a…

Machine Learning · Statistics 2022-06-09 Mingtian Zhang , Andi Zhang , Tim Z. Xiao , Yitong Sun , Steven McDonagh

Out-of-distribution detection (OOD) is a pivotal task for real-world applications that trains models to identify samples that are distributionally different from the in-distribution (ID) data during testing. Recent advances in AI,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-06 Chaohua Li , Enhao Zhang , Chuanxing Geng , Songcan Chen

Out-Of-Distribution (OOD) detection has received broad attention over the years, aiming to ensure the reliability and safety of deep neural networks (DNNs) in real-world scenarios by rejecting incorrect predictions. However, we notice a…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Yao Zhu , Yuefeng Chen , Xiaodan Li , Rong Zhang , Hui Xue , Xiang Tian , Rongxin Jiang , Bolun Zheng , Yaowu Chen

Recent works demonstrate the effectiveness of diffusion models as unsupervised solvers for inverse imaging problems. Sparse-view computed tomography (CT) has greatly benefited from these advancements, achieving improved generalization…

Image and Video Processing · Electrical Eng. & Systems 2025-05-28 Ezgi Demircan-Tureyen , Felix Lucka , Tristan van Leeuwen
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