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With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

Quantitative Methods · Quantitative Biology 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

We propose a clinical decision support system (CDSS) for mental health diagnosis that combines the strengths of large language models (LLMs) and constraint logic programming (CLP). Having a CDSS is important because of the high complexity…

Artificial Intelligence · Computer Science 2025-02-24 Brian Hyeongseok Kim , Chao Wang

Case-mix heterogeneity across studies complicates meta-analyses. As a result of this, treatments that are equally effective on patient subgroups may appear to have different effectiveness on patient populations with different case mix. It…

Applications · Statistics 2021-08-25 Tat-Thang Vo , Raphael Porcher , Anna Chaimani , Stijn Vansteelandt

Recently there has been a surge of interest in operations research (OR) and the machine learning (ML) community in combining prediction algorithms and optimization techniques to solve decision-making problems in the face of uncertainty.…

Optimization and Control · Mathematics 2025-11-11 Utsav Sadana , Abhilash Chenreddy , Erick Delage , Alexandre Forel , Emma Frejinger , Thibaut Vidal

Critical infrastructures face demanding challenges due to natural and human-generated threats, such as pandemics, workforce shortages or cyber-attacks, which might severely compromise service quality. To improve system resilience,…

Multiagent Systems · Computer Science 2025-02-11 David Carramiñana , Ana M. Bernardos , Juan A. Besada , José R. Casar

Clinical decision support systems combine knowledge and data from a variety of sources, represented by quantitative models based on stochastic methods, or qualitative based rather on expert heuristics and deductive reasoning. At the same…

Artificial Intelligence · Computer Science 2020-01-22 Ying Shen , Jacquet-Andrieu Armelle , Joël Colloc

Integrating multiple observational studies for meta-analysis has sparked much interest. The presented R package WMAP (Weighted Meta-Analysis with Pseudo-Population) addresses a critical gap in the implementation of integrative weighting…

Methodology · Statistics 2025-07-01 Subharup Guha , Mengqi Xu , Kashish Priyam , Yi Li

Multi-criteria decision-making (MCDM) problems involve the evaluation of alternatives based on various minimization and maximization criteria. Similarly, efficiency evaluation (EA) methods assess decision-making units (DMUs) by analyzing…

Optimization and Control · Mathematics 2024-06-11 Fuh-Hwa Franklin Liu , Su-Chuan Shih

The landscape of analytics is changing rapidly. Much of online user analytics, however, is based on collection of various user analytics numbers. Understanding these numbers, and then relating them to higher numerical analysis for the…

Human-Computer Interaction · Computer Science 2018-10-02 Joni Salminen , Bernard J. Jansen

This study investigates the applicability of 3D dose predictions from a model trained on one modality to a cross-modality automated planning workflow. Additionally, we explore the impact of integrating a multi-criteria optimizer on adapting…

Medical Physics · Physics 2024-02-26 Gregory Szalkowski , Xuanang Xu , Shiva Das , Pew-Thian Yap , Jun Lian

Partial identification approaches are a flexible and robust alternative to standard point-identification approaches in general instrumental variable models. However, this flexibility comes at the cost of a ``curse of cardinality'': the…

Econometrics · Economics 2020-06-30 Florian Gunsilius

In early clinical test evaluations the potential benefits of the introduction of a new technology into the healthcare system are assessed in the challenging situation of limited available empirical data. The aim of these evaluations is to…

Applications · Statistics 2020-05-21 Sara Graziadio , Kevin J. Wilson

The scheduling problem is a key class of optimization problems and has various kinds of applications both in practical and theoretical scenarios. In the scheduling problem, probabilistic analysis is a basic tool for investigating…

Information Theory · Computer Science 2024-01-30 Daiki Suruga

Use of knowledge-based planning tools can help alleviate the challenges of planning a complex operation by a coalition of diverse parties in an adversarial environment. We explore these challenges and potential contributions of…

Artificial Intelligence · Computer Science 2016-01-25 Larry Ground , Alexander Kott , Ray Budd

Causal decomposition analysis (CDA) is an approach for modeling the impact of hypothetical interventions to reduce disparities. It is useful for identifying foci that future interventions, including multilevel and multimodal interventions,…

Methodology · Statistics 2026-04-28 John W. Jackson , Ting-Hsuan Chang , Aster Meche , Trang Q. Nguyen

Healthcare decision-making requires not only accurate predictions but also insights into how factors influence patient outcomes. While traditional Machine Learning (ML) models excel at predicting outcomes, such as identifying high risk…

Machine Learning · Computer Science 2025-01-28 Sheresh Zahoor , Pietro Liò , Gaël Dias , Mohammed Hasanuzzaman

Production planning must account for uncertainty in a production system, arising from fluctuating demand forecasts. Therefore, this article focuses on the integration of updated customer demand into the rolling horizon planning cycle. We…

Econometrics · Economics 2024-09-27 Manuel Schlenkrich , Wolfgang Seiringer , Klaus Altendorfer , Sophie N. Parragh

Predicting in-hospital mortality for intensive care unit (ICU) patients is key to final clinical outcomes. AI has shown advantaged accuracy but suffers from the lack of explainability. To address this issue, this paper proposes an…

Machine Learning · Computer Science 2024-01-01 Xingqiao Li , Jindong Gu , Zhiyong Wang , Yancheng Yuan , Bo Du , Fengxiang He

The development of rigorous quality assessment model relies on the collection of reliable subjective data, where the perceived quality of visual multimedia is rated by the human observers. Different subjective assessment protocols can be…

Artificial Intelligence · Computer Science 2020-10-02 Suiyi Ling , Jing Li , Anne Flore Perrin , Zhi Li , Lukáš Krasula , Patrick Le Callet

We consider the optimization of an uncertain objective over continuous and multi-dimensional decision spaces in problems in which we are only provided with observational data. We propose a novel algorithmic framework that is tractable,…

Machine Learning · Statistics 2018-10-30 Dimitris Bertsimas , Christopher McCord