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Automated detection of anatomical landmarks plays a crucial role in many diagnostic and surgical applications. Progresses in deep learning (DL) methods have resulted in significant performance enhancement in tasks related to anatomical…

Image and Video Processing · Electrical Eng. & Systems 2024-11-28 Soorena Salari , Hassan Rivaz , Yiming Xiao

Medical tasks are prone to inter-rater variability due to multiple factors such as image quality, professional experience and training, or guideline clarity. Training deep learning networks with annotations from multiple raters is a common…

Image and Video Processing · Electrical Eng. & Systems 2023-01-13 Andreanne Lemay , Charley Gros , Enamundram Naga Karthik , Julien Cohen-Adad

Uncertainty estimation methods are expected to improve the understanding and quality of computer-assisted methods used in medical applications (e.g., neurosurgical interventions, radiotherapy planning), where automated medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-08 Alain Jungo , Raphael Meier , Ekin Ermis , Marcela Blatti-Moreno , Evelyn Herrmann , Roland Wiest , Mauricio Reyes

While multiple studies have explored the relation between inter-rater variability and deep learning model uncertainty in medical segmentation tasks, little is known about the impact of individual rater style. This study quantifies rater…

Computer Vision and Pattern Recognition · Computer Science 2021-05-06 Olivier Vincent , Charley Gros , Julien Cohen-Adad

In medical imaging, inter-observer variability among radiologists often introduces label uncertainty, particularly in modalities where visual interpretation is subjective. Lung ultrasound (LUS) is a prime example-it frequently presents a…

The problem of inter-rater variability is often discussed in the context of manual labeling of medical images. The emergence of data-driven approaches such as Deep Neural Networks (DNNs) brought this issue of raters' disagreement to the…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Or Shwartzman , Harel Gazit , Ilan Shelef , Tammy Riklin-Raviv

Uncertainty estimation of trained deep learning networks is valuable for optimizing learning efficiency and evaluating the reliability of network predictions. In this paper, we propose a method for estimating uncertainty in deep learning…

Computer Vision and Pattern Recognition · Computer Science 2024-02-15 Hansang Lee , Haeil Lee , Helen Hong , Junmo Kim

Despite the state-of-the-art performance for medical image segmentation, deep convolutional neural networks (CNNs) have rarely provided uncertainty estimations regarding their segmentation outputs, e.g., model (epistemic) and image-based…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Guotai Wang , Wenqi Li , Michael Aertsen , Jan Deprest , Sebastien Ourselin , Tom Vercauteren

Deep Learning (DL) has made remarkable achievements in computer vision and adopted in safety critical domains such as medical imaging or autonomous drive. Thus, it is necessary to understand the uncertainty of the model to effectively…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Hyekyoung Hwang , Jitae Shin

Computer-aided diagnosis systems must make critical decisions from medical images that are often noisy, ambiguous, or conflicting, yet today's models are trained on overly simplistic labels that ignore diagnostic uncertainty. One-hot labels…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Ang Nan Gu , Michael Tsang , Hooman Vaseli , Purang Abolmaesumi , Teresa Tsang

Deep learning (DL) has shown great potential in digital pathology applications. The robustness of a diagnostic DL-based solution is essential for safe clinical deployment. In this work we evaluate if adding uncertainty estimates for DL…

Machine Learning · Computer Science 2022-05-23 Milda Pocevičiūtė , Gabriel Eilertsen , Sofia Jarkman , Claes Lundström

The accuracy of deep neural networks is significantly influenced by the effectiveness of mini-batch construction during training. In single-label scenarios, such as binary and multi-class classification tasks, it has been demonstrated that…

Machine Learning · Computer Science 2024-12-24 Ao Zhou , Bin Liu , Jin Wang , Grigorios Tsoumakas

The study of model bias and variance with respect to decision boundaries is critically important in supervised classification. There is generally a tradeoff between the two, as fine-tuning of the decision boundary of a classification model…

Machine Learning · Computer Science 2020-02-25 Matthew Almeida , Wei Ding , Scott Crouter , Ping Chen

Large annotated datasets have been a key component in the success of deep learning. However, annotating medical images is challenging as it requires expertise and a large budget. In particular, annotating different types of cells in…

Computer Vision and Pattern Recognition · Computer Science 2022-10-12 Cholmin Kang , Chunggi Lee , Heon Song , Minuk Ma , S ergio Pereira

Deep Learning sets the state-of-the-art in many challenging tasks showing outstanding performance in a broad range of applications. Despite its success, it still lacks robustness hindering its adoption in medical applications. Modeling…

Computer Vision and Pattern Recognition · Computer Science 2019-09-19 Agnieszka Tomczack , Nassir Navab , Shadi Albarqouni

Uncertainty of labels in clinical data resulting from intra-observer variability can have direct impact on the reliability of assessments made by deep neural networks. In this paper, we propose a method for modelling such uncertainty in the…

Automating chest radiograph interpretation using Deep Learning (DL) models has the potential to significantly improve clinical workflows, decision-making, and large-scale health screening. However, in medical settings, merely optimising…

Computation and Language · Computer Science 2025-05-08 Gianluca Manzo , Julia Ive

One of the common issues in clinical decision-making is the presence of uncertainty, which often arises due to ambiguity in radiology reports, which often reflect genuine diagnostic uncertainty or limitations of automated label extraction…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Antik Aich Roy , Ujjwal Bhattacharya

Uncertainty-aware deep learning (DL) models recently gained attention in fault diagnosis as a way to promote the reliable detection of faults when out-of-distribution (OOD) data arise from unseen faults (epistemic uncertainty) or the…

Machine Learning · Computer Science 2024-12-30 Reza Jalayer , Masoud Jalayer , Andrea Mor , Carlotta Orsenigo , Carlo Vercellis

Automated medical image segmentation inherently involves a certain degree of uncertainty. One key factor contributing to this uncertainty is the ambiguity that can arise in determining the boundaries of a target region of interest,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-28 Qingqiao Hu , Hao Wang , Jing Luo , Yunhao Luo , Zhiheng Zhangg , Jan S. Kirschke , Benedikt Wiestler , Bjoern Menze , Jianguo Zhang , Hongwei Bran Li
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