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All text-based language problems can be reduced to either generation or embedding. Current models only perform well at one or the other. We introduce generative representational instruction tuning (GRIT) whereby a large language model is…

Computation and Language · Computer Science 2025-03-04 Niklas Muennighoff , Hongjin Su , Liang Wang , Nan Yang , Furu Wei , Tao Yu , Amanpreet Singh , Douwe Kiela

Most current molecular language models transfer the masked language model or image-text generation model from natural language processing to molecular field. However, molecules are not solely characterized by atom/bond symbols; they…

Emerging Technologies · Computer Science 2024-11-26 Yifan Wu , Min Zeng , Yang Li , Yang Zhang , Min Li

To retrieve and compare scientific data of simulations and experiments in materials science, data needs to be easily accessible and machine readable to qualify and quantify various materials science phenomena. The recent progress in open…

Materials Science · Physics 2025-03-25 Balduin Katzer , Steffen Klinder , Katrin Schulz

Large Language Models (LLMs) have garnered considerable interest within both academic and industrial. Yet, the application of LLMs to graph data remains under-explored. In this study, we evaluate the capabilities of four LLMs in addressing…

Artificial Intelligence · Computer Science 2023-09-12 Chang Liu , Bo Wu

Cross-modal text-molecule retrieval model aims to learn a shared feature space of the text and molecule modalities for accurate similarity calculation, which facilitates the rapid screening of molecules with specific properties and…

Information Retrieval · Computer Science 2024-11-01 Jia Song , Wanru Zhuang , Yujie Lin , Liang Zhang , Chunyan Li , Jinsong Su , Song He , Xiaochen Bo

Current image generation and editing methods primarily process textual prompts as direct inputs without reasoning about visual composition and explicit operations. We present Generation Chain-of-Thought (GoT), a novel paradigm that enables…

Computer Vision and Pattern Recognition · Computer Science 2025-03-14 Rongyao Fang , Chengqi Duan , Kun Wang , Linjiang Huang , Hao Li , Shilin Yan , Hao Tian , Xingyu Zeng , Rui Zhao , Jifeng Dai , Xihui Liu , Hongsheng Li

Cross-modal retrieval is gaining increasing efficacy and interest from the research community, thanks to large-scale training, novel architectural and learning designs, and its application in LLMs and multimodal LLMs. In this paper, we move…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Davide Caffagni , Sara Sarto , Marcella Cornia , Lorenzo Baraldi , Rita Cucchiara

Large Language Models (LLMs), with their remarkable task-handling capabilities and innovative outputs, have catalyzed significant advancements across a spectrum of fields. However, their proficiency within specialized domains such as…

Quantitative Methods · Quantitative Biology 2024-03-05 Yin Fang , Xiaozhuan Liang , Ningyu Zhang , Kangwei Liu , Rui Huang , Zhuo Chen , Xiaohui Fan , Huajun Chen

Medical imaging provides essential visual insights for diagnosis, and multimodal large language models (MLLMs) are increasingly utilized for its analysis due to their strong generalization capabilities; however, the underlying factors…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Zhenyang Cai , Junying Chen , Rongsheng Wang , Weihong Wang , Yonglin Deng , Dingjie Song , Yize Chen , Zixu Zhang , Benyou Wang

Molecular property prediction has gained significant attention due to its transformative potential in multiple scientific disciplines. Conventionally, a molecule graph can be represented either as a graph-structured data or a SMILES text.…

Machine Learning · Computer Science 2023-07-17 Chen Qian , Huayi Tang , Zhirui Yang , Hong Liang , Yong Liu

The development of large language models and multi-modal models has enabled the appealing idea of generating novel molecules from text descriptions. Generative modeling would shift the paradigm from relying on large-scale chemical screening…

Machine Learning · Computer Science 2025-08-25 Yifan Deng , Spencer S. Ericksen , Anthony Gitter

This paper presents Graph-of-Thought (GoT), a new model for workflow automation that enhances the flexibility and efficiency of Large Language Models (LLMs) in complex task execution. GoT advances beyond traditional linear and tree-like…

Artificial Intelligence · Computer Science 2024-02-20 Ye Li

Compared to traditional sentiment analysis, which only considers text, multimodal sentiment analysis needs to consider emotional signals from multimodal sources simultaneously and is therefore more consistent with the way how humans process…

Computation and Language · Computer Science 2024-08-19 Hao Yang , Yanyan Zhao , Yang Wu , Shilong Wang , Tian Zheng , Hongbo Zhang , Zongyang Ma , Wanxiang Che , Bing Qin

The disruptive technology provided by large-scale pre-trained language models (LLMs) such as ChatGPT or GPT-4 has received significant attention in several application domains, often with an emphasis on high-level opportunities and…

Human-Computer Interaction · Computer Science 2023-06-27 Philippe J. Giabbanelli

With the emergence of diffusion models as a frontline generative model, many researchers have proposed molecule generation techniques with conditional diffusion models. However, the unavoidable discreteness of a molecule makes it difficult…

Machine Learning · Computer Science 2025-06-05 Jinho Chang , Jong Chul Ye

The GPT (Generative Pre-trained Transformer) language models are an artificial intelligence and natural language processing technology that enables automatic text generation. There is a growing interest in applying GPT language models to…

Computers and Society · Computer Science 2024-03-25 Manuel de Buenaga , Francisco Javier Bueno

The recent advancements in auto-regressive multimodal large language models (MLLMs) have demonstrated promising progress for vision-language tasks. While there exists a variety of studies investigating the processing of linguistic…

Artificial Intelligence · Computer Science 2025-03-28 Zhi Zhang , Srishti Yadav , Fengze Han , Ekaterina Shutova

In recent years, molecular representation learning has emerged as a key area of focus in various chemical tasks. However, many existing models fail to fully consider the geometric information of molecular structures, resulting in less…

Machine Learning · Computer Science 2023-06-29 Bumju Kwak , Jiwon Park , Taewon Kang , Jeonghee Jo , Byunghan Lee , Sungroh Yoon

High-quality textual training data is essential for the success of multimodal data processing tasks, yet outputs from image captioning models like BLIP and GIT often contain errors and anomalies that are difficult to rectify using…

Computation and Language · Computer Science 2025-02-25 Elyas Meguellati , Nardiena Pratama , Shazia Sadiq , Gianluca Demartini

Aligning molecular sequence representations (e.g., SMILES notations) with textual descriptions is critical for applications spanning drug discovery, materials design, and automated chemical literature analysis. Existing methodologies…

Artificial Intelligence · Computer Science 2025-11-25 Letian Chen , Runhan Shi , Gufeng Yu , Yang Yang