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Chain-of-thought (CoT) reasoning has exhibited impressive performance in language models for solving complex tasks and answering questions. However, many real-world questions require multi-modal information, such as text and images.…

Artificial Intelligence · Computer Science 2023-12-15 Liqi He , Zuchao Li , Xiantao Cai , Ping Wang

The application of supervised models to clinical screening tasks is challenging due to the need for annotated data for each considered pathology. Unsupervised Anomaly Detection (UAD) is an alternative approach that aims to identify any…

Image and Video Processing · Electrical Eng. & Systems 2025-01-24 Finn Behrendt , Debayan Bhattacharya , Robin Mieling , Lennart Maack , Julia Krüger , Roland Opfer , Alexander Schlaefer

Spatial profiling technologies in biology, such as imaging mass cytometry (IMC) and spatial transcriptomics (ST), generate high-dimensional, multi-channel data with strong spatial alignment and complex inter-channel relationships.…

Machine Learning · Computer Science 2025-07-08 Haoran Zhang , Mingyuan Zhou , Wesley Tansey

This paper investigates steady state solutions of a vasculogenesis model governed by coupled partial differential equations in a bounded two dimensional domain. Explicit steady state solutions are analytically constructed, and their…

Analysis of PDEs · Mathematics 2026-03-31 Sinchita Lahiri , Kun Zhao

This paper presents OC-DiT, a novel class of diffusion models designed for object-centric prediction, and applies it to zero-shot instance segmentation. We propose a conditional latent diffusion framework that generates instance masks by…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Maximilian Ulmer , Wout Boerdijk , Rudolph Triebel , Maximilian Durner

Diffusion models have shown impressive potential on talking head generation. While plausible appearance and talking effect are achieved, these methods still suffer from temporal, 3D or expression inconsistency due to the error accumulation…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Haijie Yang , Zhenyu Zhang , Hao Tang , Jianjun Qian , Jian Yang

Diffusion models have shown remarkable capacity in image synthesis based on their U-shaped architecture and convolutional neural networks (CNN) as basic blocks. The locality of the convolution operation in CNN may limit the model's ability…

Computer Vision and Pattern Recognition · Computer Science 2025-12-19 Shaohua Wu , Tong Yu , Shenling Wang , Xudong Zhao

Can we train a 3D molecule generator using data from dense regions to generate samples in sparse regions? This challenge can be framed as an out-of-distribution (OOD) generation problem. While prior research on OOD generation predominantly…

Machine Learning · Computer Science 2026-03-03 Haokai Hong , Wanyu Lin , Ming Yang , Kay Chen Tan

Turbulent flows have historically presented formidable challenges to predictive computational modeling. Traditional numerical simulations often require vast computational resources, making them infeasible for numerous engineering…

Fluid Dynamics · Physics 2023-11-15 Han Gao , Xu Han , Xiantao Fan , Luning Sun , Li-Ping Liu , Lian Duan , Jian-Xun Wang

Physics-informed deep learning has been developed as a novel paradigm for learning physical dynamics recently. While general physics-informed deep learning methods have shown early promise in learning fluid dynamics, they are difficult to…

Fluid Dynamics · Physics 2024-06-07 Jing Qiu , Jiancheng Huang , Xiangdong Zhang , Zeng Lin , Minglei Pan , Zengding Liu , Fen Miao

Lacunes of presumed vascular origin (lacunes) are associated with an increased risk of stroke, gait impairment, and dementia and are a primary imaging feature of the small vessel disease. Quantification of lacunes may be of great importance…

Electrical waves in the heart form rotating spiral or scroll waves during life-threatening arrhythmias such as atrial or ventricular fibrillation. The wave dynamics are typically modeled using coupled partial differential equations, which…

Medical Physics · Physics 2024-10-07 Tanish Baranwal , Jan Lebert , Jan Christoph

Medical image segmentation is inherently an ambiguous task due to factors such as partial volumes and variations in anatomical definitions. While in most cases the segmentation uncertainty is around the border of structures of interest,…

Machine Learning · Statistics 2020-08-05 Raghavendra Selvan , Frederik Faye , Jon Middleton , Akshay Pai

Despite the remarkable generative capabilities of diffusion models, their integration into safety-critical or scientifically rigorous applications remains hindered by the need to ensure compliance with stringent physical, structural, and…

Machine Learning · Computer Science 2025-06-03 Jacob K. Christopher , Michael Cardei , Jinhao Liang , Ferdinando Fioretto

We present a new method for modeling tissue perfusion on the capillary scale. The microvasculature is represented by a network of one-dimensional vessel segments embedded in the extra-vascular space. Vascular and extra-vascular space…

Computational Physics · Physics 2020-03-23 Timo Koch , Martin Schneider , Rainer Helmig , Patrick Jenny

Conditional diffusion models serve as the foundation of modern image synthesis and find extensive application in fields like computational biology and reinforcement learning. In these applications, conditional diffusion models incorporate…

Machine Learning · Computer Science 2024-03-19 Hengyu Fu , Zhuoran Yang , Mengdi Wang , Minshuo Chen

The advent of deep learning has introduced efficient approaches for de novo protein sequence design, significantly improving success rates and reducing development costs compared to computational or experimental methods. However, existing…

Artificial Intelligence · Computer Science 2024-07-11 Yutong Hu , Yang Tan , Andi Han , Lirong Zheng , Liang Hong , Bingxin Zhou

Low-field (LF) MRI scanners (<1T) are still prevalent in settings with limited resources or unreliable power supply. However, they often yield images with lower spatial resolution and contrast than high-field (HF) scanners. This quality…

Image and Video Processing · Electrical Eng. & Systems 2023-11-14 Seunghoi Kim , Henry F. J. Tregidgo , Ahmed K. Eldaly , Matteo Figini , Daniel C. Alexander

Collaborative 3D object detection holds significant importance in the field of autonomous driving, as it greatly enhances the perception capabilities of each individual agent by facilitating information exchange among multiple agents.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-05 Zhe Huang , Shuo Wang , Yongcai Wang , Lei Wang

We propose a diffusion model designed to generate point-based shape representations with correspondences. Traditional statistical shape models have considered point correspondences extensively, but current deep learning methods do not take…

Computer Vision and Pattern Recognition · Computer Science 2025-08-07 Shen Zhu , Yinzhu Jin , Ifrah Zawar , P. Thomas Fletcher