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Accurate multiclass segmentation of the Circle of Willis (CoW) is essential for neurovascular disease management but remains challenging due to complex vascular topology and variable morphology. Existing deep learning methods often suffer…

Machine Learning · Computer Science 2026-05-01 Jialu Liu , Yue Cui , Shan Yu

Anatomy shape modeling is a fundamental problem in medical data analysis. However, the geometric complexity and topological variability of anatomical structures pose significant challenges to accurate anatomical shape generation. In this…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Guoqing Zhang , Jingyun Yang , Siqi Chen , Anping Zhang , Yang Li

We present a novel alignment-before-generation approach to tackle the challenging task of generating general 3D shapes based on 2D images or texts. Directly learning a conditional generative model from images or texts to 3D shapes is prone…

Computer Vision and Pattern Recognition · Computer Science 2023-07-04 Zibo Zhao , Wen Liu , Xin Chen , Xianfang Zeng , Rui Wang , Pei Cheng , Bin Fu , Tao Chen , Gang Yu , Shenghua Gao

This paper presents a new approach for 3D shape generation, enabling direct generative modeling on a continuous implicit representation in wavelet domain. Specifically, we propose a compact wavelet representation with a pair of coarse and…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Ka-Hei Hui , Ruihui Li , Jingyu Hu , Chi-Wing Fu

We introduce a new technique for generating retinal fundus images that have anatomically accurate vascular structures, using diffusion models. We generate artery/vein masks to create the vascular structure, which we then condition to…

Image and Video Processing · Electrical Eng. & Systems 2023-05-12 Sojung Go , Younghoon Ji , Sang Jun Park , Soochahn Lee

Originating from the diffusion phenomenon in physics, which describes the random movement and collisions of particles, diffusion generative models simulate a random walk in the data space along the denoising trajectory. This allows…

Computer Vision and Pattern Recognition · Computer Science 2026-05-08 Yuhan Pei , Ruoyu Wang , Yongqi Yang , Ye Zhu , Olga Russakovsky , Yu Wu

Generative models have attracted significant interest due to their ability to handle uncertainty by learning the inherent data distributions. However, two prominent generative models, namely Generative Adversarial Networks (GANs) and…

Machine Learning · Computer Science 2023-04-25 Yu Wang , Zhiwei Liu , Liangwei Yang , Philip S. Yu

This paper contributes to the "BraTS 2024 Brain MR Image Synthesis Challenge" and presents a conditional Wavelet Diffusion Model (cWDM) for directly solving a paired image-to-image translation task on high-resolution volumes. While deep…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Paul Friedrich , Alicia Durrer , Julia Wolleb , Philippe C. Cattin

Segmentation of brain structures from MRI is crucial for evaluating brain morphology, yet existing CNN and transformer-based methods struggle to delineate complex structures accurately. While current diffusion models have shown promise in…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qilong Xing , Zikai Song , Yuteng Ye , Yuke Chen , Youjia Zhang , Na Feng , Junqing Yu , Wei Yang

Large generative diffusion models have revolutionized text-to-image generation and offer immense potential for conditional generation tasks such as image enhancement, restoration, editing, and compositing. However, their widespread adoption…

Computer Vision and Pattern Recognition · Computer Science 2024-02-20 Kangfu Mei , Mauricio Delbracio , Hossein Talebi , Zhengzhong Tu , Vishal M. Patel , Peyman Milanfar

Learning robust representations of 3D shapes from voxelized data is essential for advancing AI methods in biomedical imaging. However, most contemporary 3D computer vision approaches operate on point clouds, meshes, or octrees, while…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Rui Li , Artsemi Yushkevich , Mikhail Kudryashev , Artur Yakimovich

Diffusion models are important in tissue engineering as they enable an understanding of molecular delivery to cells in tissue constructs. As three-dimensional (3D) tissue constructs become larger, more intricate, and more clinically…

Tissues and Organs · Quantitative Biology 2015-12-22 Richard J. McMurtrey

Recent advances in denoising diffusion probabilistic models have shown great success in image synthesis tasks. While there are already works exploring the potential of this powerful tool in image semantic segmentation, its application in…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Xinrong Hu , Yu-Jen Chen , Tsung-Yi Ho , Yiyu Shi

Deep neural networks have brought remarkable breakthroughs in medical image analysis. However, due to their data-hungry nature, the modest dataset sizes in medical imaging projects might be hindering their full potential. Generating…

Applying machine learning to real-world medical data, e.g. from hospital archives, has the potential to revolutionize disease detection in brain images. However, detecting pathology in such heterogeneous cohorts is a difficult challenge.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Ana Lawry Aguila , Ayodeji Ijishakin , Juan Eugenio Iglesias , Tomomi Takenaga , Yukihiro Nomura , Takeharu Yoshikawa , Osamu Abe , Shouhei Hanaoka

The field of neural rendering has witnessed significant progress with advancements in generative models and differentiable rendering techniques. Though 2D diffusion has achieved success, a unified 3D diffusion pipeline remains unsettled.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Yushi Lan , Fangzhou Hong , Shangchen Zhou , Shuai Yang , Xuyi Meng , Yongwei Chen , Zhaoyang Lyu , Bo Dai , Xingang Pan , Chen Change Loy

Generating realistic 3D point clouds is a fundamental problem in computer vision with applications in remote sensing, robotics, and digital object modeling. Existing generative approaches primarily capture geometry, and when semantics are…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Gunner Stone , Sushmita Sarker , Alireza Tavakkoli

MRI synthesis promises to mitigate the challenge of missing MRI modality in clinical practice. Diffusion model has emerged as an effective technique for image synthesis by modelling complex and variable data distributions. However, most…

Image and Video Processing · Electrical Eng. & Systems 2023-03-27 Lan Jiang , Ye Mao , Xi Chen , Xiangfeng Wang , Chao Li

Recent advances in generative models for medical imaging have shown promise in representing multiple modalities. However, the variability in modality availability across datasets limits the general applicability of the synthetic data they…

Image and Video Processing · Electrical Eng. & Systems 2024-10-02 Sven Lüpke , Yousef Yeganeh , Ehsan Adeli , Nassir Navab , Azade Farshad

In this article, we present a Latent Diffusion Model (LDM) for the generation of brain Magnetic Resonance Imaging (MRI), conditioning its generation based on pathology (Healthy, Glioblastoma, Sclerosis, Dementia) and acquisition modality…