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Denoising low-dose computed tomography (CT) images is a critical task in medical image computing. Supervised deep learning-based approaches have made significant advancements in this area in recent years. However, these methods typically…

Image and Video Processing · Electrical Eng. & Systems 2023-07-17 Xuan Liu , Yaoqin Xie , Jun Cheng , Songhui Diao , Shan Tan , Xiaokun Liang

Low Dose Computed Tomography (LDCT) is clinically desirable due to the reduced radiation to patients. However, the quality of LDCT images is often sub-optimal because of the inevitable strong quantum noise. Inspired by their unprecedent…

Image and Video Processing · Electrical Eng. & Systems 2021-02-02 Ti Bai , Dan Nguyen , Biling Wang , Steve Jiang

Low dose computed tomography (LDCT) is desirable for both diagnostic imaging and image guided interventions. Denoisers are openly used to improve the quality of LDCT. Deep learning (DL)-based denoisers have shown state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2020-12-08 Ti Bai , Biling Wang , Dan Nguyen , Bao Wang , Bin Dong , Wenxiang Cong , Mannudeep K. Kalra , Steve Jiang

With its significant performance improvements, the deep learning paradigm has become a standard tool for modern image denoisers. While promising performance has been shown on seen noise distributions, existing approaches often suffer from…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Hao Chen , Chenyuan Qu , Yu Zhang , Chen Chen , Jianbo Jiao

Deep learning approaches in image processing predominantly resort to supervised learning. A majority of methods for image denoising are no exception to this rule and hence demand pairs of noisy and corresponding clean images. Only recently…

Image and Video Processing · Electrical Eng. & Systems 2020-10-02 Priyatham Kattakinda , A. N. Rajagopalan

In clinical examinations and diagnoses, low-dose computed tomography (LDCT) is crucial for minimizing health risks compared with normal-dose computed tomography (NDCT). However, reducing the radiation dose compromises the signal-to-noise…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Haoyu Zhao , Yuliang Gu , Zhou Zhao , Bo Du , Yongchao Xu , Rui Yu

Supervised deep networks have achieved promisingperformance on image denoising, by learning image priors andnoise statistics on plenty pairs of noisy and clean images. Unsupervised denoising networks are trained with only noisy images.…

Computer Vision and Pattern Recognition · Computer Science 2020-10-28 Jun Xu , Yuan Huang , Ming-Ming Cheng , Li Liu , Fan Zhu , Zhou Xu , Ling Shao

The explosive rise of the use of Computer tomography (CT) imaging in medical practice has heightened public concern over the patient's associated radiation dose. However, reducing the radiation dose leads to increased noise and artifacts,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-06 Sutanu Bera , Prabir Kumar Biswas

Low-dose computed tomography (LDCT) is critical for minimizing radiation exposure, but it often leads to increased noise and reduced image quality. Traditional denoising methods, such as iterative optimization or supervised learning, often…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Debopom Sutradhar , Ripon Kumar Debnath , Mohaimenul Azam Khan Raiaan , Yan Zhang , Reem E. Mohamed , Sami Azam

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

To reduce the potential radiation risk, low-dose CT has attracted much attention. However, simply lowering the radiation dose will lead to significant deterioration of the image quality. In this paper, we propose a noise reduction method…

Medical Physics · Physics 2016-10-04 Hu Chen , Yi Zhang , Weihua Zhang , Peixi Liao , Ke Li , Jiliu Zhou , Ge Wang

Image denoising is of great importance for medical imaging system, since it can improve image quality for disease diagnosis and downstream image analyses. In a variety of applications, dynamic imaging techniques are utilized to capture the…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Junshen Xu , Elfar Adalsteinsson

We describe a novel method for training high-quality image denoising models based on unorganized collections of corrupted images. The training does not need access to clean reference images, or explicit pairs of corrupted images, and can…

Machine Learning · Computer Science 2019-10-29 Samuli Laine , Tero Karras , Jaakko Lehtinen , Timo Aila

Recently, denoising methods based on supervised learning have exhibited promising performance. However, their reliance on external datasets containing noisy-clean image pairs restricts their applicability. To address this limitation,…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Jaekyun Ko , Sanghwan Lee

Image denoising techniques are essential to reducing noise levels and enhancing diagnosis reliability in low-dose computed tomography (CT). Machine learning based denoising methods have shown great potential in removing the complex and…

Computer Vision and Pattern Recognition · Computer Science 2017-08-29 Dufan Wu , Kyungsang Kim , Georges El Fakhri , Quanzheng Li

Self-supervised learning has been increasingly investigated for low-dose computed tomography (LDCT) image denoising, as it alleviates the dependence on paired normal-dose CT (NDCT) data, which are often difficult to collect. However, many…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Yichao Liu , Zongru Shao , Yueyang Teng , Junwen Guo

Image denoising of low-dose computed tomography (LDCT) is an important problem for clinical diagnosis with reduced radiation exposure. Previous methods are mostly trained with pairs of synthetic or misaligned LDCT and normal-dose CT (NDCT)…

Image and Video Processing · Electrical Eng. & Systems 2025-02-04 Junhao Long , Fengwei Yang , Juncheng Yan , Baoping Zhang , Chao Jin , Jian Yang , Changliang Zou , Jun Xu

Deep neural network based methods are the state of the art in various image restoration problems. Standard supervised learning frameworks require a set of noisy measurement and clean image pairs for which a distance between the output of…

Image and Video Processing · Electrical Eng. & Systems 2021-03-31 Rihuan Ke , Carola-Bibiane Schönlieb

Commercial iterative reconstruction techniques on modern CT scanners target radiation dose reduction but there are lingering concerns over their impact on image appearance and low contrast detectability. Recently, machine learning,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-16 Hongming Shan , Atul Padole , Fatemeh Homayounieh , Uwe Kruger , Ruhani Doda Khera , Chayanin Nitiwarangkul , Mannudeep K. Kalra , Ge Wang

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Qi Gao , Zhihao Chen , Dong Zeng , Junping Zhang , Jianhua Ma , Hongming Shan