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The mining of adverse drug events (ADEs) is pivotal in pharmacovigilance, enhancing patient safety by identifying potential risks associated with medications, facilitating early detection of adverse events, and guiding regulatory…

Artificial Intelligence · Computer Science 2024-10-04 Pranab Sahoo , Ayush Kumar Singh , Sriparna Saha , Aman Chadha , Samrat Mondal

Active adverse event surveillance monitors Adverse Drug Events (ADE) from different data sources, such as electronic health records, medical literature, social media and search engine logs. Over the years, many datasets have been created,…

Computation and Language · Computer Science 2024-11-26 Xiang Dai , Sarvnaz Karimi , Abeed Sarker , Ben Hachey , Cecile Paris

Document-level event extraction (DEE) faces two main challenges: arguments-scattering and multi-event. Although previous methods attempt to address these challenges, they overlook the interference of event-unrelated sentences during event…

Computation and Language · Computer Science 2023-10-17 Gang Zhao , Yidong Shi , Shudong Lu , Xinjie Yang , Guanting Dong , Jian Xu , Xiaocheng Gong , Si Li

Document-level event extraction aims to extract structured event information from unstructured text. However, a single document often contains limited event information and the roles of different event arguments may be biased due to the…

Computation and Language · Computer Science 2024-08-27 Qiang Gao , Zixiang Meng , Bobo Li , Jun Zhou , Fei Li , Chong Teng , Donghong Ji

Capturing interactions among event arguments is an essential step towards robust event argument extraction (EAE). However, existing efforts in this direction suffer from two limitations: 1) The argument role type information of contextual…

Computation and Language · Computer Science 2021-07-02 Xiangyu Xi , Wei Ye , Shikun Zhang , Quanxiu Wang , Huixing Jiang , Wei Wu

Adverse reaction caused by drugs is a potentially dangerous problem which may lead to mortality and morbidity in patients. Adverse Drug Event (ADE) extraction is a significant problem in biomedical research. We model ADE extraction as a…

Computation and Language · Computer Science 2018-01-03 Suriyadeepan Ramamoorthy , Selvakumar Murugan

Drug similarity has been studied to support downstream clinical tasks such as inferring novel properties of drugs (e.g. side effects, indications, interactions) from known properties. The growing availability of new types of drug features…

Machine Learning · Computer Science 2018-05-01 Tengfei Ma , Cao Xiao , Jiayu Zhou , Fei Wang

Adverse drug events (ADEs) are unexpected incidents caused by the administration of a drug or medication. To identify and extract these events, we require information about not just the drug itself but attributes describing the drug (e.g.,…

Computation and Language · Computer Science 2021-04-23 Darshini Mahendran , Bridget T. McInnes

Adverse drug events (ADEs) are an important aspect of drug safety. Various texts such as biomedical literature, drug reviews, and user posts on social media and medical forums contain a wealth of information about ADEs. Recent studies have…

Computation and Language · Computer Science 2024-05-21 Shaoxiong Ji , Ya Gao , Pekka Marttinen

Events and entities are closely related; entities are often actors or participants in events and events without entities are uncommon. The interpretation of events and entities is highly contextually dependent. Existing work in information…

Computation and Language · Computer Science 2016-09-14 Bishan Yang , Tom Mitchell

Few works in the literature of event extraction have gone beyond individual sentences to make extraction decisions. This is problematic when the information needed to recognize an event argument is spread across multiple sentences. We argue…

Computation and Language · Computer Science 2020-05-15 Xinya Du , Claire Cardie

We propose SemCSE-Multi, a novel unsupervised framework for generating multifaceted embeddings of scientific abstracts, evaluated in the domains of invasion biology and medicine. These embeddings capture distinct, individually specifiable…

Computation and Language · Computer Science 2026-01-13 Marc Brinner , Sina Zarrieß

Relation Extraction (RE) has been extended to cross-document scenarios because many relations are not simply described in a single document. This inevitably brings the challenge of efficient open-space evidence retrieval to support the…

Computation and Language · Computer Science 2023-06-06 Keming Lu , I-Hung Hsu , Wenxuan Zhou , Mingyu Derek Ma , Muhao Chen

In recent years, Internet users are reporting Adverse Drug Events (ADE) on social media, blogs and health forums. Because of the large volume of reports, pharmacovigilance is seeking to resort to NLP to monitor these outlets. We propose for…

Computation and Language · Computer Science 2021-05-20 Beatrice Portelli , Daniele Passabì , Edoardo Lenzi , Giuseppe Serra , Enrico Santus , Emmanuele Chersoni

In the realm of cancer treatment, summarizing adverse drug events (ADEs) reported by patients using prescribed drugs is crucial for enhancing pharmacovigilance practices and improving drug-related decision-making. While the volume and…

Computation and Language · Computer Science 2025-05-08 Sofia Jamil , Aryan Dabad , Bollampalli Areen Reddy , Sriparna Saha , Rajiv Misra , Adil A. Shakur

Joint-event-extraction, which extracts structural information (i.e., entities or triggers of events) from unstructured real-world corpora, has attracted more and more research attention in natural language processing. Most existing works do…

Computation and Language · Computer Science 2020-10-15 Yue Wang , Zhuo Xu , Lu Bai , Yao Wan , Lixin Cui , Qian Zhao , Edwin R. Hancock , Philip S. Yu

Cross encoders (CEs) are trained with sentence pairs to detect relatedness. As CEs require sentence pairs at inference, the prevailing view is that they can only be used as re-rankers in information retrieval pipelines. Dual encoders (DEs)…

Computation and Language · Computer Science 2025-02-07 Haritha Ananthakrishnan , Julian Dolby , Harsha Kokel , Horst Samulowitz , Kavitha Srinivas

We consider the problem of collectively detecting multiple events, particularly in cross-sentence settings. The key to dealing with the problem is to encode semantic information and model event inter-dependency at a document-level. In this…

Computation and Language · Computer Science 2022-11-02 Dongfang Lou , Zhilin Liao , Shumin Deng , Ningyu Zhang , Huajun Chen

Adverse drug events (ADEs) are a major safety issue in clinical trials. Thus, predicting ADEs is key to developing safer medications and enhancing patient outcomes. To support this effort, we introduce CT-ADE, a dataset for multilabel ADE…

Computation and Language · Computer Science 2025-03-11 Anthony Yazdani , Alban Bornet , Philipp Khlebnikov , Boya Zhang , Hossein Rouhizadeh , Poorya Amini , Douglas Teodoro

Early identification of Adverse Drug Events (ADE) is critical for taking prompt actions while introducing new drugs into the market. These ADEs information are available through various unstructured data sources like clinical study reports,…

Computation and Language · Computer Science 2024-12-23 Vinayak Arannil , Tomal Deb , Atanu Roy
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