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Related papers: Non-Markovian gene expression

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We study finite state random dynamical systems (RDS) and their induced Markov chains (MC) as stochastic models for complex dynamics. The linear representation of deterministic maps in RDS are matrix-valued random variables whose…

Dynamical Systems · Mathematics 2020-03-23 Felix X. -F. Ye , Hong Qian

Spontaneous emission of a quantum emitter, such as an excited atom, is a fundamental process in quantum electrodynamics (QED), typically associated with exponential decay to the ground state accompanied by irreversible photon emission. This…

Quantum Physics · Physics 2026-04-16 Stefano Longhi

In this work we construct individual-based models that give rise to the generalized logistic model at the mean-field deterministic level and that allow us to interpret the parameters of these models in terms of individual interactions. We…

Populations and Evolution · Quantitative Biology 2017-09-13 Vicenc Mendez , Michael Assaf , Werner Horsthemke , Daniel Campos

Molecular dynamics (MD) is a central computational tool in physics, chemistry, and biology, enabling quantitative prediction of experimental observables as expectations over high-dimensional molecular distributions such as Boltzmann…

Machine Learning · Computer Science 2026-02-13 Panagiotis Antoniadis , Beatrice Pavesi , Simon Olsson , Ole Winther

It is known that the dynamical evolution of a system, from an initial tensor product state of system and environment, to any two later times, t1,t2 (t2>t1), are both completely positive (CP) but in the intermediate times between t1 and t2…

Quantum Physics · Physics 2013-05-07 A. R. Usha Devi , A. K. Rajagopal , Sudha , R. W. Rendell

A considerable number of systems have recently been reported in which Brownian yet non-Gaussian dynamics was observed. These are processes characterised by a linear growth in time of the mean squared displacement, yet the probability…

Statistical Mechanics · Physics 2018-11-26 V. Sposini , A. V. Chechkin , F. Seno , G. Pagnini , R. Metzler

We show that nonequilibrium dynamics can play a constructive role in unsupervised machine learning by inducing the spontaneous emergence of latent-state cycles. We introduce a model in which visible and hidden variables interact through two…

Statistical Mechanics · Physics 2026-05-05 Marco Baiesi , Alberto Rosso

Simple, controllable models play an important role to learn how to manipulate and control quantum resources. We focus here on quantum non-Markovianity and model the evolution of open quantum systems by quantum renewal processes. This class…

Quantum Physics · Physics 2021-08-04 Nina Megier , Manuel Ponzi , Andrea Smirne , Bassano Vacchini

In genetic circuits, when the mRNA lifetime is short compared to the cell cycle, proteins are produced in geometrically-distributed bursts, which greatly affects the cellular switching dynamics between different metastable phenotypic…

Statistical Mechanics · Physics 2016-05-25 Shay Be'er , Metar Heller-Algazi , Michael Assaf

Continuous-time Markov chains are used to model stochastic systems where transitions can occur at irregular times, e.g., birth-death processes, chemical reaction networks, population dynamics, and gene regulatory networks. We develop a…

Machine Learning · Statistics 2022-12-13 Majerle Reeves , Harish S. Bhat

There is mounting evidence that species interactions often involve long-term memory, with highly-varying waiting times between successive events and long-range temporal correlations. Accounting for memory undermines the common Markovian…

Populations and Evolution · Quantitative Biology 2025-11-24 Ohad Vilk , Mauro Mobilia , Michael Assaf

In the present Short Note an idea is proposed to explain the emergence and the observation of processes in complex media that are driven by fractional non-Markovian master equations. Particle trajectories are assumed to be solely Markovian…

Statistical Mechanics · Physics 2015-06-19 Gianni Pagnini

We study a stochastic model of protein dynamics that explicitly includes delay in the degradation. We rigorously derive the master equation for the processes and solve it exactly. We show that the equations for the mean values obtained…

Statistical Mechanics · Physics 2013-05-29 Luis F. Lafuerza , Raul Toral

The mean-field dynamics of a particle in a random, but short range correlated potential, offers the opportunity of observing both aging and driven stationary regimes. Using a geometrical approach previously introduced by the author, we…

Condensed Matter · Physics 2009-10-31 Fabrice Thalmann

A Markovian dichotomic system driven by a deterministic time-periodic force is analyzed in terms of the statistical properties of the switching events between the states. The consideration of the counting process of the switching events…

Statistical Mechanics · Physics 2009-11-10 Jesús Casado-Pascual , José Gómez-Ordóñez , M. Morillo

We discuss fundamental features of the local expression for the entropy production rate of the nonequilibrium quantum dynamics of open systems and its relations to memory effects and the spectrum of the generator of the dynamics. Defining…

Quantum Physics · Physics 2026-03-03 Irene Ada Picatoste , Alessandra Colla , Heinz-Peter Breuer

We investigate a kinetic model of a system in contact with several thermal reservoirs at different temperatures $T_\alpha$. Our system is a spatially uniform dilute gas whose internal dynamics is described by the nonlinear Boltzmann…

Mathematical Physics · Physics 2014-06-17 Eric A. Carlen , Joel L. Lebowitz , Clement Mouhot

Recent experiments using fluorescence spectroscopy have been able to probe the dynamics of conformational fluctuations in proteins. The fluctuations are Gaussian but do not decay exponentially, and are therefore, non-Markovian. We present a…

Statistical Mechanics · Physics 2008-10-14 Arti Dua , R. Adhikari

Discrete-state stochastic models are a popular approach to describe the inherent stochasticity of gene expression in single cells. The analysis of such models is hindered by the fact that the underlying discrete state space is extremely…

Analysis of PDEs · Mathematics 2021-01-28 Pavel Kurasov , Delio Mugnolo , Verena Wolf

We formulate a general, high-dimensional kinetic theory describing the internal state (such as gene expression or protein levels) of cells in a stochastically evolving population. The resolution of our kinetic theory also allows one to…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Tom Chou
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