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Eosinophilic esophagitis (EoE) is a chronic esophageal disorder marked by eosinophil-dominated inflammation. Diagnosing EoE usually involves endoscopic inspection of the esophageal mucosa and obtaining esophageal biopsies for histologic…

Image and Video Processing · Electrical Eng. & Systems 2025-02-07 Juming Xiong , Hou Xiong , Quan Liu , Ruining Deng , Regina N Tyree , Girish Hiremath , Yuankai Huo

Goal: Eosinophilic esophagitis (EoE) is an allergic inflammatory condition characterized by eosinophil accumulation in the esophageal mucosa. EoE diagnosis includes a manual assessment of eosinophil levels in mucosal biopsies - a…

Computer Vision and Pattern Recognition · Computer Science 2021-01-14 Tomer Czyzewski , Nati Daniel , Mark Rochman , Julie M. Caldwell , Garrett A. Osswald , Margaret H. Collins , Marc E. Rothenberg , Yonatan Savir

Eosinophilic Esophagitis (EoE) is an inflammatory esophageal disease which is increasing in prevalence. The diagnostic gold-standard involves manual review of a patient's biopsy tissue sample by a clinical pathologist for the presence of 15…

Image and Video Processing · Electrical Eng. & Systems 2021-01-15 William Adorno , Alexis Catalano , Lubaina Ehsan , Hans Vitzhum von Eckstaedt , Barrett Barnes , Emily McGowan , Sana Syed , Donald E. Brown

Background. Eosinophilic esophagitis (EoE) is an allergic inflammatory condition of the esophagus associated with elevated numbers of eosinophils. Disease diagnosis and monitoring requires determining the concentration of eosinophils in…

Eosinophilic esophagitis (EoE) is a chronic allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. Second only to gastroesophageal reflux disease, EoE is one of the leading causes of chronic…

Eosinophilic esophagitis (EoE) is a chronic, food antigen-driven, allergic inflammatory condition of the esophagus associated with elevated esophageal eosinophils. EoE is a top cause of chronic dysphagia after GERD. Diagnosis of EoE relies…

Eosinophilic esophagitis (EoE) is a chronic and relapsing disease characterized by esophageal inflammation. Symptoms of EoE include difficulty swallowing, food impaction, and chest pain which significantly impact the quality of life,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yilin Liu , Ruining Deng , Juming Xiong , Regina N Tyree , Hernan Correa , Girish Hiremath , Yaohong Wang , Yuankai Huo

Eosinophilic Esophagitis (EoE) is an allergic condition increasing in prevalence. To diagnose EoE, pathologists must find 15 or more eosinophils within a single high-power field (400X magnification). Determining whether or not a patient has…

Image and Video Processing · Electrical Eng. & Systems 2023-11-09 Kevin Lin , Donald Brown , Sana Syed , Adam Greene

Chronic rhinosinusitis (CRS) is characterized by persistent inflammation in the paranasal sinuses, leading to typical symptoms of nasal congestion, facial pressure, olfactory dysfunction, and discolored nasal drainage, which can…

Image and Video Processing · Electrical Eng. & Systems 2024-11-26 Yifei Wu , Juming Xiong , Tianyuan Yao , Ruining Deng , Junlin Guo , Jialin Yue , Naweed Chowdhury , Yuankai Huo

Normally eosinophils are present in the gastrointestinal (GI) tract of healthy individuals. When the eosinophils increase beyond their usual amount in the GI tract, a patient gets varied symptoms. Clinicians find it difficult to diagnose…

Quantitative Methods · Quantitative Biology 2022-11-30 Harsh Shah , Thomas Jacob , Amruta Parulekar , Anjali Amarapurkar , Amit Sethi

Accurate segmentation of lesions is crucial for diagnosis and treatment of early esophageal cancer (EEC). However, neither traditional nor deep learning-based methods up to today can meet the clinical requirements, with the mean Dice score…

Image and Video Processing · Electrical Eng. & Systems 2023-06-12 Haipeng Li , Dingrui Liu , Yu Zeng , Shuaicheng Liu , Tao Gan , Nini Rao , Jinlin Yang , Bing Zeng

Purpose: Exercise-induced pulmonary hemorrhage (EIPH) is a common syndrome in sport horses with negative impact on performance. Cytology of bronchoalveolar lavage fluid by use of a scoring system is considered the most sensitive diagnostic…

Objective: To systematically evaluate the value of endocytoscopy (ECS) in the diagnosis of early esophageal cancer (EC). Methods: Pubmed, Ovid and EMbase databases were searched to collect diagnostic tests of ECS assisted diagnosis of early…

Tissues and Organs · Quantitative Biology 2023-01-10 Lu Wang , Bofu Tang , Feifei Liu , Zhenyu Jiang , Xianmei Meng

Endoscopy is a crucial tool for diagnosing the gastrointestinal tract, but its effectiveness is often limited by a narrow field of view and the dynamic nature of the internal environment, especially in the esophagus, where complex and…

Computer Vision and Pattern Recognition · Computer Science 2024-10-03 Muyang Li , Juming Xiong , Ruining Deng , Tianyuan Yao , Regina N Tyree , Girish Hiremath , Yuankai Huo

Early detection of esophagitis is important because this condition can progress to cancer if left untreated. However, the accuracies of different deep learning models in detecting esophagitis have yet to be compared. Thus, this study aimed…

Image and Video Processing · Electrical Eng. & Systems 2023-01-09 Kyoka Yoshiok , Kensuke Tanioka , Satoru Hiwa , Tomoyuki Hiroyasu

Video endoscopy represents a major advance in the investigation of gastrointestinal diseases. Reviewing endoscopy videos often involves frequent adjustments and reorientations to piece together a complete view, which can be both…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Juming Xiong , Muyang Li , Ruining Deng , Tianyuan Yao , Shunxing Bao , Regina N Tyree , Girish Hiremath , Yuankai Huo

Artificial intelligence (AI) has transformed digital pathology by enabling biomarker prediction from high-resolution whole-slide images (WSIs). However, current methods are computationally inefficient, processing thousands of redundant…

Deep learning-based methods, such as the sliding window approach for cropped-image classification and heuristic aggregation for whole-slide inference, for analyzing histological patterns in high-resolution microscopy images have shown…

Image and Video Processing · Electrical Eng. & Systems 2019-12-05 Naofumi Tomita , Behnaz Abdollahi , Jason Wei , Bing Ren , Arief Suriawinata , Saeed Hassanpour

Oral epithelial dysplasia (OED) is a premalignant histopathological diagnosis given to lesions of the oral cavity. Its grading suffers from significant inter-/intra- observer variability, and does not reliably predict malignancy…

Most existing Human-Object Interaction~(HOI) Detection methods rely heavily on full annotations with predefined HOI categories, which is limited in diversity and costly to scale further. We aim at advancing zero-shot HOI detection to detect…

Computer Vision and Pattern Recognition · Computer Science 2022-11-28 Mingrui Wu , Jiaxin Gu , Yunhang Shen , Mingbao Lin , Chao Chen , Xiaoshuai Sun
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