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Deep learning approaches are superior in NLP due to their ability to extract informative features and patterns from languages. The two most successful neural architectures are LSTM and transformers, used in large pretrained language models…

Computation and Language · Computer Science 2022-03-03 Matej Klemen , Luka Krsnik , Marko Robnik-Šikonja

Therapeutic peptides have emerged as a pivotal modality in modern drug discovery, occupying a chemically and topologically rich space. While accurate prediction of their physicochemical properties is essential for accelerating peptide…

Machine Learning · Computer Science 2025-12-30 Seungeon Lee , Takuto Koyama , Itsuki Maeda , Shigeyuki Matsumoto , Yasushi Okuno

The massive scale and growth of textual biomedical data have made its indexing and classification increasingly important. However, existing research on this topic mainly utilized convolutional and recurrent neural networks, which generally…

Computation and Language · Computer Science 2022-03-08 Bruce Nguyen , Shaoxiong Ji

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim

There is a long history of building predictive models in healthcare using tabular data from electronic medical records. However, these models fail to extract the information found in unstructured clinical notes, which document diagnosis,…

Computation and Language · Computer Science 2025-04-18 David Anderson , Michaela Anderson , Margret Bjarnadottir , Stephen Mahar , Shriyan Reyya

Professionals in modern healthcare systems are increasingly burdened by documentation workloads. Documentation of the initial patient anamnesis is particularly relevant, forming the basis of successful further diagnostic measures. However,…

Computation and Language · Computer Science 2020-11-04 Anton Schäfer , Nils Blach , Oliver Rausch , Maximilian Warm , Nils Krüger

ClinicalEncoder26AM is a multilingual Diagnosable ColBERT for clinical and biomedical texts, which aligns at multiple levels its token-level semantic with ClinicalMap25, a clinical latent space inspired by BioLORD-2023 and enriched with…

Computation and Language · Computer Science 2026-05-28 François Remy

Large language models have exhibited exceptional performance on various Natural Language Processing (NLP) tasks, leveraging techniques such as the pre-training, and instruction fine-tuning. Despite these advances, their effectiveness in…

Computation and Language · Computer Science 2023-06-19 Guangyu Wang , Guoxing Yang , Zongxin Du , Longjun Fan , Xiaohu Li

Recent years have witnessed a substantial increase in the use of deep learning to solve various natural language processing (NLP) problems. Early deep learning models were constrained by their sequential or unidirectional nature, such that…

Information Retrieval · Computer Science 2024-03-05 Jiajia Wang , Jimmy X. Huang , Xinhui Tu , Junmei Wang , Angela J. Huang , Md Tahmid Rahman Laskar , Amran Bhuiyan

We propose a new Named entity recognition (NER) method to effectively make use of the results of Part-of-speech (POS) tagging, Chinese word segmentation (CWS) and parsing while avoiding NER error caused by POS tagging error. This paper…

Computation and Language · Computer Science 2021-01-28 Xiao Fu , Guijun Zhang

Hypergraphs are characterized by complex topological structure, representing higher-order interactions among multiple entities through hyperedges. Lately, hypergraph-based deep learning methods to learn informative data representations for…

Machine Learning · Computer Science 2024-09-30 Adrián Bazaga , Pietro Liò , Gos Micklem

The United States has experienced a significant increase in violent extremism, prompting the need for automated tools to detect and limit the spread of extremist ideology online. This study evaluates the performance of Bidirectional Encoder…

Computation and Language · Computer Science 2024-08-30 Beidi Dong , Jin R. Lee , Ziwei Zhu , Balassubramanian Srinivasan

Large-scale transformer-based models like the Bidirectional Encoder Representations from Transformers (BERT) are widely used for Natural Language Processing (NLP) applications, wherein these models are initially pre-trained with a large…

Computation and Language · Computer Science 2023-10-09 Mohammad Wali Ur Rahman , Murad Mehrab Abrar , Hunter Gibbons Copening , Salim Hariri , Sicong Shao , Pratik Satam , Soheil Salehi

Automatic pathological speech detection approaches have shown promising results, gaining attention as potential diagnostic tools alongside costly traditional methods. While these approaches can achieve high accuracy, their lack of…

Audio and Speech Processing · Electrical Eng. & Systems 2025-04-01 Mahdi Amiri , Hatef Otroshi Shahreza , Ina Kodrasi

In the expansion of biomedical dataset, the same category may be labeled with different terms, thus being tedious and onerous to curate these terms. Therefore, automatically mapping synonymous terms onto the ontologies is desirable, which…

Computation and Language · Computer Science 2023-11-29 Hanwen Xu , Jiayou Zhang , Zhirui Wang , Shizhuo Zhang , Megh Manoj Bhalerao , Yucong Liu , Dawei Zhu , Sheng Wang

In the field of image-based drug discovery, capturing the phenotypic response of cells to various drug treatments and perturbations is a crucial step. However, existing methods require computationally extensive and complex multi-step…

Machine Learning · Computer Science 2025-02-28 Bo Li , Bob Zhang , Chengyang Zhang , Minghao Zhou , Weiliang Huang , Shihang Wang , Qing Wang , Mengran Li , Yong Zhang , Qianqian Song

Rare diseases are challenging to diagnose due to limited patient data and genetic diversity. Despite advances in variant prioritization, many cases remain undiagnosed. While large language models (LLMs) have performed well in medical exams,…

Motivation: A perennial challenge for biomedical researchers and clinical practitioners is to stay abreast with the rapid growth of publications and medical notes. Natural language processing (NLP) has emerged as a promising direction for…

Computation and Language · Computer Science 2021-12-16 Robert Tinn , Hao Cheng , Yu Gu , Naoto Usuyama , Xiaodong Liu , Tristan Naumann , Jianfeng Gao , Hoifung Poon

Large language models (LLMs) have demonstrated remarkable capabilities for medical question answering and programming, but their potential for generating interpretable computable phenotypes (CPs) is under-explored. In this work, we…

Machine Learning · Computer Science 2025-08-08 Guilherme Seidyo Imai Aldeia , Daniel S. Herman , William G. La Cava

We present a Three-level Hierarchical Transformer Network (3-level-HTN) for modeling long-term dependencies across clinical notes for the purpose of patient-level prediction. The network is equipped with three levels of Transformer-based…

Computation and Language · Computer Science 2021-12-20 Yuqi Si , Kirk Roberts