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Early detection and diagnosis of coronary artery disease (CAD) could save lives and reduce healthcare costs. The current clinical practice is to perform CAD diagnosis through analysing medical images from computed tomography coronary…

Medical Informatics and the application of modern signal processing in the assistance of the diagnostic process in medical imaging is one of the more recent and active research areas today. This thesis addresses a variety of issues related…

Computer Vision and Pattern Recognition · Computer Science 2009-10-20 Harris Georgiou

Enhancing the precision of segmenting coronary atherosclerotic plaques from CT Angiography (CTA) images is pivotal for advanced Coronary Atherosclerosis Analysis (CAA), which distinctively relies on the analysis of vessel cross-section…

Image and Video Processing · Electrical Eng. & Systems 2025-01-15 Ziheng Zhang , Zihan Li , Dandan Shan , Yuehui Qiu , Qingqi Hong , Qingqiang Wu

Coronary heart disease (CHD) caused by hardening of artery walls due to cholesterol known as atherosclerosis is responsible for large number of deaths world-wide. The disease progression is slow, asymptomatic and may lead to sudden cardiac…

Machine Learning · Computer Science 2015-02-03 V. Sree Hari Rao , M. Naresh Kumar

Extensive studies suggested that fluid mechanical markers of intracranial aneurysms (IAs) derived from Computational Fluid Dynamics (CFD) can indicate disease progression risks, but to date this has not been translated clinically. This is…

Machine Learning · Computer Science 2026-01-30 Yiying Sheng , Wenhao Ding , Dylan Roi , Leonard Leong Litt Yeo , Hwa Liang Leo , Choon Hwai Yap

Intravascular ultrasound and optical coherence tomography are widely available for characterizing coronary stenoses and provide critical vessel parameters to optimize percutaneous intervention. Intravascular polarization-sensitive optical…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Mohammad Haft-Javaherian , Martin Villiger , Kenichiro Otsuka , Joost Daemen , Peter Libby , Polina Golland , Brett E. Bouma

Hemodynamic quantities are valuable biomedical risk factors for cardiovascular pathology such as atherosclerosis. Non-invasive, in-vivo measurement of these quantities can only be performed using a select number of modalities that are not…

Quantitative Methods · Quantitative Biology 2026-02-23 Julian Suk , Dieuwertje Alblas , Barbara A. Hutten , Albert Wiegman , Christoph Brune , Pim van Ooij , Jelmer M. Wolterink

In patients with obstructive coronary artery disease, the functional significance of a coronary artery stenosis needs to be determined to guide treatment. This is typically established through fractional flow reserve (FFR) measurement,…

Image and Video Processing · Electrical Eng. & Systems 2019-11-12 Majd Zreik , Robbert W. van Hamersvelt , Nadieh Khalili , Jelmer M. Wolterink , Michiel Voskuil , Max A. Viergever , Tim Leiner , Ivana Išgum

Computational hemodynamics is becoming an increasingly important tool in clinical applications and surgical procedures involving the cardiovascular system. Aim of this review is to provide a compact summary of state of the art 0D-1D…

Medical Physics · Physics 2022-01-03 Stefania Scarsoglio , Luca Ridolfi

Cardiovascular Diseases (CVD) and strokes produce immense health and economic burdens globally. Coronary Artery Disease (CAD) is the most common type of cardiovascular disease. Coronary Angiography, which is an invasive treatment, is also…

Artificial Intelligence · Computer Science 2020-05-22 Ioannis Apostolopoulos , Peter Groumpos

Coronary stenosis is a major risk factor for ischemic heart events leading to increased mortality, and medical treatments for this condition require meticulous, labor-intensive analysis. Coronary angiography provides critical visual cues…

Image and Video Processing · Electrical Eng. & Systems 2025-08-04 Sumin Seo , In Kyu Lee , Hyun-Woo Kim , Jaesik Min , Chung-Hwan Jung

Cardiovascular disease is a large worldwide healthcare issue; symptoms often present suddenly with minimal warning. The electrocardiogram (ECG) is a fast, simple and reliable method of evaluating the health of the heart, by measuring…

Signal Processing · Electrical Eng. & Systems 2022-01-15 Yola Jones , Fani Deligianni , Jeff Dalton

Cerebrovascular diseases such as brain aneurysms are a primary cause of adult disability. The flow dynamics in brain arteries, both during periods of rest and increased activity, are known to be a major factor in the risk of aneurysm…

Distributed, Parallel, and Cluster Computing · Computer Science 2015-04-30 Mohamed A. Itani , Ulf D. Schiller , Sebastian Schmieschek , James Hetherington , Miguel O. Bernabeu , Hoskote Chandrashekar , Fergus Robertson , Peter V. Coveney , Derek Groen

Automatically identifying the structural substrates underlying cardiac abnormalities can potentially provide real-time guidance for interventional procedures. With the knowledge of cardiac tissue substrates, the treatment of complex…

Image and Video Processing · Electrical Eng. & Systems 2022-06-10 Ziyi Huang , Yu Gan , Theresa Lye , Yanchen Liu , Haofeng Zhang , Andrew Laine , Elsa Angelini , Christine Hendon

Visual analytics (VA) systems have been widely used in various application domains. However, VA systems are complex in design, which imposes a serious problem: although the academic community constantly designs and implements new designs,…

Human-Computer Interaction · Computer Science 2024-02-27 Lu Ying , Aoyu Wu , Haotian Li , Zikun Deng , Ji Lan , Jiang Wu , Yong Wang , Huamin Qu , Dazhen Deng , Yingcai Wu

Atherosclerosis is one of the principle pathologies of cardiovascular disease with blood cholesterol a significant risk factor. The World Health Organisation estimates that approximately 2.5 million deaths occur annually due to the risk…

Tissues and Organs · Quantitative Biology 2015-10-08 Andrew Parton , Victoria McGilligan , Maurice OKane , Francina R Baldrick , Steven Watterson

Coronary angiography remains the gold standard for diagnosis of coronary artery disease, the most common cause of death worldwide. While this procedure is performed more than 2 million times annually, there remain few methods for fast and…

Image and Video Processing · Electrical Eng. & Systems 2023-10-25 Tom Liu , Hui Lin , Aggelos K. Katsaggelos , Adrienne Kline

With coronary artery disease (CAD) persisting to be one of the leading causes of death worldwide, interest in supporting physicians with algorithms to speed up and improve diagnosis is high. In clinical practice, the severeness of CAD is…

Coronary angiography is the "gold standard" for diagnosing coronary artery disease (CAD). At present, the methods for detecting and evaluating coronary artery stenosis cannot satisfy the clinical needs, e.g., there is no prior study of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-15 Yaofang Liu , Xinyue Zhang , Wenlong Wan , Shaoyu Liu , Yingdi Liu , Hu Liu , Xueying Zeng , Qing Zhang

Coronary angiography is the "gold standard" for diagnosing coronary artery disease (CAD). At present, the methods for detecting and evaluating coronary artery stenosis cannot satisfy the clinical needs, e.g., there is no prior study of…

Image and Video Processing · Electrical Eng. & Systems 2021-12-16 Yaofang Liu , Xinyue Zhang , Wenlong Wan , Shaoyu Liu , Yingdi Liu , Hu Liu , Xueying Zeng , Qing Zhang