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The analysis of plaque deposits in the coronary vasculature is an important topic in current clinical research. From a technical side mostly new algorithms for different sub tasks - e.g. centerline extraction or vessel/plaque segmentation -…

Computer Vision and Pattern Recognition · Computer Science 2021-01-12 Felix Denzinger , Michael Wels , Christian Hopfgartner , Jing Lu , Max Schöbinger , Andreas Maier , Michael Sühling

In this work, we investigate how concepts from medical flow visualization can be applied to enhance stroke prevention diagnostics. Our focus lies on carotid stenoses, i.e., local narrowings of the major brain-supplying arteries, which are a…

Medical Physics · Physics 2021-04-07 Pepe Eulzer , Monique Meuschke , Carsten Klingner , Kai Lawonn

Advanced atherosclerosis in the coronary arteries is one of the leading causes of deaths worldwide while being preventable and treatable. In order to image atherosclerotic lesions (plaque), intravascular optical coherence tomography (IVOCT)…

Computer Vision and Pattern Recognition · Computer Science 2018-06-11 Nils Gessert , Markus Heyder , Sarah Latus , Matthias Lutz , Alexander Schlaefer

Coronary heart disease is a common cause of death despite being preventable. To treat the underlying plaque deposits in the arterial walls, intravascular optical coherence tomography can be used by experts to detect and characterize the…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Nils Gessert , Matthias Lutz , Markus Heyder , Sarah Latus , David M. Leistner , Youssef S. Abdelwahed , Alexander Schlaefer

Purpose: Enabling a comprehensive and robust assessment of carotid artery plaques in 3D through extraction and visualization of quantitative plaque parameters. These parameters have potential applications in stroke risk analysis, evaluation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-24 Hinrich Rahlfs , Markus Hüllebrand , Sebastian Schmitter , Christoph Strecker , Andreas Harloff , Anja Hennemuth

Atherosclerosis of the carotid artery increases stroke risk. Atherosclerosis assessment with MRI requires multimodal and multidimensional segmentation of the carotid artery, reproducible extraction of biomarkers, and the visualization of…

Image and Video Processing · Electrical Eng. & Systems 2026-03-24 Hinrich Rahlfs , Markus Hüllebrand , Sebastian Schmitter , Jonathan Andrae , Christoph Strecker , Andreas Harloff , Anja Hennemuth

Analysing the haemodynamics of flow in carotid artery disease serves as a means to better understand the development and progression of associated complex diseases. Carotid artery disease can predispose people to major adverse…

Carotid atherosclerosis is the major cause of ischemic stroke resulting in significant rates of mortality and disability annually. Early diagnosis of such cases is of great importance, since it enables clinicians to apply a more effective…

Image and Video Processing · Electrical Eng. & Systems 2022-02-08 Theofanis Ganitidis , Maria Athanasiou , Kalliopi Dalakleidi , Nikos Melanitis , Spyretta Golemati , Konstantina S Nikita

During the diagnosis of ischemic strokes, the Circle of Willis and its surrounding vessels are the arteries of interest. Their visualization in case of an acute stroke is often enabled by Computed Tomography Angiography (CTA). Still, the…

Image and Video Processing · Electrical Eng. & Systems 2022-04-27 Florian Thamm , Markus Jürgens , Oliver Taubmann , Aleksandra Thamm , Leonhard Rist , Hendrik Ditt , Andreas Maier

Coronary artery disease (CAD) remains the leading cause of death worldwide. Patients with suspected CAD undergo coronary CT angiography (CCTA) to evaluate the risk of cardiovascular events and determine the treatment. Clinical analysis of…

Coronary artery disease (CAD) remains the leading cause of death globally and invasive coronary angiography (ICA) is considered the gold standard of anatomical imaging evaluation when CAD is suspected. However, risk evaluation based on ICA…

Targeted diagnosis and treatment plans for patients with coronary artery disease vary according to atherosclerotic plaque component. Coronary CT angiography (CCTA) is widely used for artery imaging and determining the stenosis degree.…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Jun Li , Kexin Li , Yafeng Zhou , S. Kevin Zhou

The key manifestation of coronary artery disease (CAD) is development of fibroatheromatous plaque, the cap of which may rupture and subsequently lead to coronary artery blocking and heart attack. As such, quantitative analysis of coronary…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Yaopeng Peng , Zhi Chen , Andreas Wahle , Tomas Kovarnik , Milan Sonk , Danny Z. Chen

The analysis of carotid arteries, particularly plaques, in multi-sequence Magnetic Resonance Imaging (MRI) data is crucial for assessing the risk of atherosclerosis and ischemic stroke. In order to evaluate metrics and radiomic features,…

Image and Video Processing · Electrical Eng. & Systems 2025-07-11 Marie-Christine Pali , Christina Schwaiger , Malik Galijasevic , Valentin K. Ladenhauf , Stephanie Mangesius , Elke R. Gizewski

Recent advancements in Artificial Intelligence (AI) have significantly influenced the field of Cardiovascular Disease (CVD) analysis, particularly in image-based diagnostics. Our paper presents an extensive review of AI applications in…

Image and Video Processing · Electrical Eng. & Systems 2025-12-12 Xin Wang , Mingcheng Hu , Connie W. Tsao , Hongtu Zhu

Coronary artery disease, the leading cause of cardiovascular mortality worldwide, can be assessed non-invasively by coronary computed tomography angiography (CCTA). Despite progress in automated CCTA analysis using deep learning, clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Jinkui Hao , Gorkem Durak , Halil Ertugrul Aktas , Ulas Bagci , Bradley D. Allen , Nilay S. Shah , Bo Zhou

Artificial intelligence (AI) methodologies hold great promise for the rapid and accurate diagnosis of coronary artery disease (CAD) from intravascular optical coherent tomography (IVOCT) images. Numerous papers have been published…

Image and Video Processing · Electrical Eng. & Systems 2025-02-03 Xu Chen , Yuan Huang , Benn Jessney , Jason Sangha , Sophie Gu , Carola-Bibiane Schönlieb , Martin Bennett , Michael Roberts

Epidemiology characterizes the influence of causes to disease and health conditions of defined populations. Cohort studies are population-based studies involving usually large numbers of randomly selected individuals and comprising numerous…

Computer Vision and Pattern Recognition · Computer Science 2015-01-19 Bernhard Preim , Paul Klemm , Helwig Hauser , Katrin Hegenscheid , Steffen Oeltze , Klaus Toennies , Henry Völzke

In carotid arteries, plaque can develop as localized elevated lesions. The Jellyfish sign, marked by fluctuating plaque surfaces with blood flow pulsation, is a dynamic characteristic of these plaques that has recently attracted attention.…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Takeshi Yoshidomi , Shinji Kume , Hiroaki Aizawa , Akira Furui

Accurate characterization of carotid plaques is critical for stroke prevention in patients with carotid stenosis. We analyze 500 plaques from CREST-2, a multi-center clinical trial, to identify radiomics-based markers from B-mode ultrasound…

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