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The availability of digital twins for the cardiovascular system will enable insightful computational tools both for research and clinical practice. This, however, demands robust and well defined models and methods for the different steps…

Computational Engineering, Finance, and Science · Computer Science 2024-11-21 Pau Romero , Abel Pedrós , Rafael Sebastian , Miguel Lozano , Ignacio García-Fernández

Dielectric elastomers are widely studied for their use in robotic and medical devices due to their shape changing properties. Recently, they have also been incorporated into acoustic devices, motivating the development of an electroacoustic…

Fluid Dynamics · Physics 2023-06-07 C. Solano , Y. Zhang , L. N. Cattafesta

A theoretical model of thermal boundary layers and acoustic heating in microscale acoustofluidic devices is presented. It includes effective boundary conditions allowing for simulations in three dimensions. The model is extended by an…

Fluid Dynamics · Physics 2021-12-21 Jonas Helboe Joergensen , Henrik Bruus

The manipulation of acoustic wave propagation in fluids has numerous applications, including some in everyday life. Acoustic technologies frequently develop in tandem with optics, using shared concepts such as waveguiding and metamedia. It…

Mesoscale and Nanoscale Physics · Physics 2015-03-24 Zhaoju Yang , Fei Gao , Xihang Shi , Xiao Lin , Zhen Gao , Yidong Chong , Baile Zhang

A model of vesicle electrodeformation is described which obtains a parametrized vesicle shape by minimizing the sum of the membrane bending energy and the energy due to the electric field. Both the vesicle membrane and the aqueous media…

Biological Physics · Physics 2010-08-23 Primoz Peterlin

The interaction of targeted drug carriers with epithelial and endothelial barriers in vivo is largely determined by the dynamics of the body fluids. To simulate these conditions in binding assays, a fully biocompatible in vitro model was…

Acoustic waves can generate steady streaming within a fluid owing to the generation of viscous boundary layers near walls, of typical thickness $\delta$. In microchannels, the acoustic wavelength $\lambda$ is adjusted to twice the channel…

Fluid Dynamics · Physics 2020-11-04 Chuanyu Zhang , Xiaofeng Guo , Laurent Royon , Philippe Brunet

The way living tissues respond to external mechanical forces is crucial in physiological processes like embryogenesis, homeostasis or tumor growth. Providing a complete description across length scales which relates the properties of…

Soft Condensed Matter · Physics 2025-11-07 Majid Layachi , Remi Merindol , Laura Casanellas

Making use of the poroelastic theory for hydrated polymeric matrices, the ultrasound (US) propagation in a gel medium filled by spherical cells is studied . The model describes the connection between the poroelastic structure of living…

Soft Condensed Matter · Physics 2012-10-10 Piero Chiarelli , Bruna Vinci , Antonio Lanatá , Clara Lagomarsini , Simone Chiarelli

We demonstrate theoretically that acoustic forces acting on inhomogeneous fluids can be used to pattern and manipulate solute concentration fields into spatio-temporally controllable configurations stabilized against gravity. A theoretical…

Fluid Dynamics · Physics 2017-03-29 Jonas T. Karlsen , Henrik Bruus

In this paper, we present a unit cell showing a band-gap in the lower acoustic domain. The corresponding metamaterial is made up of a periodic arrangement of this unit cell. We rigorously show that the relaxed micromorphic model can be used…

Applied Physics · Physics 2022-09-07 F. Demore , G. Rizzi , M. Collet , P. Neff , A. Madeo

Lipid vesicles consist of aqueous cores surrounded by a bilayer of phospholipids. Hybrid polymer-lipid vesicles incorporate both polymers and lipids, offering promising properties for developing pharmaceuticals, biosensors, and artificial…

The dynamics of active viscoelastic surfaces plays an important role in biological systems. One prominent example is the actin cortex, a thin bio-polymer sheet underneath the outer membrane of biological cells which combines active…

Ultrasound waves propagating in water or soft biological tissue are strongly reflected when encountering the skull, which limits the use of ultrasound-based techniques in transcranial imaging and therapeutic applications. Current knowledge…

Medical Physics · Physics 2017-06-07 Héctor Estrada , Johannes Rebling , Daniel Razansky

The efficient mixing of fluid samples in miniaturized total analysis systems is essential for numerous applications including biological screening assays, chemical extraction, polymerization, cell analysis, and protein folding. Miniaturized…

Fluid Dynamics · Physics 2022-10-25 S. A. Iqrar , J. Park , M. Afzal , H. J. Sung

Inexpensive, portable lab-on-a-chip devices would revolutionize fields like environmental monitoring and global health, but current microfluidic chips are tethered to extensive off-chip hardware. Insects, however, are self-contained and…

Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…

Fluid Dynamics · Physics 2025-08-04 Maxx Yung

The steady motion and deformation of a lipid-bilayer vesicle translating through a circular tube in low Reynolds number pressure-driven flow are investigated numerically using an axisymmetric boundary element method. This fluid-structure…

Fluid Dynamics · Physics 2020-05-05 Paul G. Chen , J. M. Lyu , M. Jaeger , M. Leonetti

In this paper, we present an approach to ultrasonic beam-forming and beam-steering in structures based on the concept of embedded non-resonant acoustic metamaterial lenses. The lens design exploits the principle of acoustic drop-channel…

Classical Physics · Physics 2015-06-22 Hongfei Zhu , Fabio Semperlotti

On-chip cavity optomechanics, in which strong co-localization of light and mechanical motion is engineered, relies on efficient coupling of light both into and out of the on-chip optical resonator. Here we detail our particular style of…

Mesoscale and Nanoscale Physics · Physics 2014-05-19 Bradley D Hauer , Paul H Kim , Callum Doolin , Allison JR MacDonald , Hugh Ramp , John P Davis