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Topological data analysis is an emerging field that applies the study of topological invariants to data. Perhaps the simplest of these invariants is the number of connected components or clusters. In this work, we explore a topological…

Computational Geometry · Computer Science 2023-12-19 Ian Stewart Joyce , Grant Erdmann , Kirk P. Gardner , Ryan Kramer , Kyle Siegrist

The theory of multidimensional persistent homology was initially developed in the discrete setting, and involved the study of simplicial complexes filtered through an ordering of the simplices. Later, stability properties of…

Computational Geometry · Computer Science 2013-03-28 Niccolò Cavazza , Marc Ethier , Patrizio Frosini , Tomasz Kaczynski , Claudia Landi

Topological Data Analysis (TDA) has emerged as a powerful framework for extracting robust and interpretable features from noisy high-dimensional data. In the context of Social Choice Theory, where preference profiles and collective…

Algebraic Topology · Mathematics 2025-07-22 Athanasios Andrikopoulos , Nikolaos Sampanis

Algebraic topology has been widely applied to point cloud data to capture geometric shapes and topological structures. However, its application to genome sequence analysis remains rare. In this work, we propose topological sequence analysis…

Algebraic Topology · Mathematics 2025-07-09 Jian Liu , Li Shen , Dong Chen , Guo-Wei Wei

A fundamental tool in topological data analysis is persistent homology, which allows extraction of information from complex datasets in a robust way. Persistent homology assigns a module over a principal ideal domain to a one-parameter…

Algebraic Topology · Mathematics 2019-06-19 Heather A. Harrington , Nina Otter , Hal Schenck , Ulrike Tillmann

Understanding the response of an output variable to multi-dimensional inputs lies at the heart of many data exploration endeavours. Topology-based methods, in particular Morse theory and persistent homology, provide a useful framework for…

Graphics · Computer Science 2022-08-16 Yarden Livnat , Dan Maljovec , Attila Gyulassy , Dr Baptiste Mouginot , Valerio Pascucci

Topological data analysis (TDA) studies the shape patterns of data. Persistent homology is a widely used method in TDA that summarizes homological features of data at multiple scales and stores them in persistence diagrams (PDs). In this…

Machine Learning · Statistics 2022-09-16 Theodore Papamarkou , Farzana Nasrin , Austin Lawson , Na Gong , Orlando Rios , Vasileios Maroulas

A time-delay embedding (TDE), grounded in the framework of Takens's Theorem, provides a mechanism to represent and analyze the inherent dynamics of time-series data. Recently, topological data analysis (TDA) methods have been applied to…

Methodology · Statistics 2024-10-18 Sixtus Dakurah , Jessi Cisewski-Kehe

We propose a study of multipartite entanglement through persistent homology, a tool used in topological data analysis. In persistent homology, a 1-parameter filtration of simplicial complexes called persistence complex is used to reveal…

Quantum Physics · Physics 2024-06-05 Gregory A. Hamilton , Felix Leditzky

The natural occurrence of singular spaces in applications has led to recent investigations on performing topological data analysis (TDA) in a stratified framework. In many applications, there is no a priori information on what points should…

Algebraic Topology · Mathematics 2023-12-12 Tim Mäder , Lukas Waas

Accurate prediction of Drug-Target Affinity (DTA) is crucial for reducing experimental costs and accelerating early screening in computational drug discovery. While sequence-based deep learning methods avoid reliance on costly 3D…

Machine Learning · Computer Science 2025-11-03 Minghui Li , Yuanhang Wang , Peijin Guo , Wei Wan , Shengshan Hu , Shengqing Hu

Various kinds of data are routinely represented as discrete probability distributions. Examples include text documents summarized by histograms of word occurrences and images represented as histograms of oriented gradients. Viewing a…

Computational Geometry · Computer Science 2019-03-29 Herbert Edelsbrunner , Ziga Virk , Hubert Wagner

Topological data analysis, as a tool for extracting topological features and characterizing geometric shapes, has experienced significant development across diverse fields. Its key mathematical techniques include persistent homology and the…

Algebraic Topology · Mathematics 2024-04-19 Jian Liu , Dong Chen , Guo-Wei Wei

Convolutional neural networks (CNNs) are a standard tool for computer vision tasks such as image classification. However, typical model architectures may result in the loss of topological information. In specific domains such as…

Image and Video Processing · Electrical Eng. & Systems 2026-03-05 Shrunal Pothagoni , Benjamin Schweinhart

Accurate and interpretable brain tumor classification from medical imaging remains a challenging problem due to the high dimensionality and complex structural patterns present in magnetic resonance imaging (MRI). In this study, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Faisal Ahmed

Complex prediction models such as deep learning are the output from fitting machine learning, neural networks, or AI models to a set of training data. These are now standard tools in science. A key challenge with the current generation of…

Machine Learning · Computer Science 2022-10-21 Meng Liu , Tamal K. Dey , David F. Gleich

Topological data analysis (TDA) offers novel mathematical tools for deep learning. Inspired by Carlsson et al., this study designs topology-aware convolutional kernels that significantly improve speech recognition networks. Theoretically,…

Machine Learning · Computer Science 2025-05-28 Zhiwang Yu

Appropriately representing elements in a database so that queries may be accurately matched is a central task in information retrieval; recently, this has been achieved by embedding the graphical structure of the database into a manifold in…

Machine Learning · Statistics 2023-07-10 Yueqi Cao , Athanasios Vlontzos , Luca Schmidtke , Bernhard Kainz , Anthea Monod

This paper introduces topological data analysis. Starting from notions of a metric space and some elementary graph theory, we take example sets of data and demonstrate some of their topological properties. We discuss simplicial complexes…

History and Overview · Mathematics 2020-04-09 Dayten Sheffar

Biomolecular structure comparison not only reveals evolutionary relationships, but also sheds light on biological functional properties. However, traditional definitions of structure or sequence similarity always involve superposition or…

Quantitative Methods · Quantitative Biology 2017-07-13 Kelin Xia