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Recent advancements in AI agents have demonstrated their growing potential to drive and support scientific discovery. In this work, we introduce MLR-Bench, a comprehensive benchmark for evaluating AI agents on open-ended machine learning…

Machine Learning · Computer Science 2025-10-23 Hui Chen , Miao Xiong , Yujie Lu , Wei Han , Ailin Deng , Yufei He , Jiaying Wu , Yibo Li , Yue Liu , Bryan Hooi

We analyze the challenges of benchmarking scientific (multi)-agentic systems, including the difficulty of distinguishing reasoning from retrieval, the risks of data/model contamination, the lack of reliable ground truth for novel research…

Computers and Society · Computer Science 2026-04-07 Marcin Abram

Accelerated material discovery increasingly relies on artificial intelligence and machine learning, collectively termed "AI/ML". A key challenge in using AI is ensuring that human scientists trust the models are valid and reliable.…

Materials Science · Physics 2025-12-02 Benhour Amirian , Ashley S. Dale , Sergei Kalinin , Jason Hattrick-Simpers

Large Language Models (LLMs) demonstrate potentials for automating scientific code generation but face challenges in reliability, error propagation in multi-agent workflows, and evaluation in domains with ill-defined success metrics. We…

Artificial Intelligence · Computer Science 2026-03-04 Zihang Zeng , Jiaquan Zhang , Pengze Li , Yuan Qi , Xi Chen

As AI becomes more common in students' everyday experiences, a major challenge for K-12 AI education is designing learning experiences that can be meaningfully integrated into existing subject-area instruction. This paper presents the…

Computers and Society · Computer Science 2026-04-16 Griffin Pitts , Kimia Fazeli , Tirth Bhatt , Jennifer Albert , Marnie Hill , Tiffany Barnes , Shiyan Jiang , Bita Akram

Benchmarks are pivotal in driving AI progress, and invalid benchmark questions frequently undermine their reliability. Manually identifying and correcting errors among thousands of benchmark questions is not only infeasible but also a…

Scientific discovery is a complex cognitive process that has driven human knowledge and technological progress for centuries. While artificial intelligence (AI) has made significant advances in automating aspects of scientific reasoning,…

Machine Learning · Computer Science 2024-12-24 Chandan K Reddy , Parshin Shojaee

Medical data poses a daunting challenge for AI algorithms: it exists in many different modalities, experiences frequent distribution shifts, and suffers from a scarcity of examples and labels. Recent advances, including transformers and…

Machine learning (ML) is increasingly adopted in scientific research, yet the quality and reliability of results often depend on how experiments are designed and documented. Poor baselines, inconsistent preprocessing, or insufficient…

Machine Learning · Computer Science 2025-12-01 Umberto Michelucci , Francesca Venturini

The transformative potential of artificial intelligence (AI) in medical Imaging (MI) is well recognized. Yet despite promising reports in research settings, many AI tools fail to achieve clinical adoption in practice. In fact, more…

Medical Physics · Physics 2025-11-26 Ahmad Fayaz-Bakhsh , Janice Tania , Syaheerah Lebai Lutfi , Abhinav K. Jha , Arman Rahmim

The ongoing artificial intelligence (AI) revolution has the potential to change almost every line of work. As AI capabilities continue to improve in accuracy, robustness, and reach, AI may outperform and even replace human experts across…

Digital Libraries · Computer Science 2024-06-04 Jian Gao , Dashun Wang

Machine-learning force fields (MLFFs) have emerged as a promising solution for speeding up ab initio molecular dynamics (MD) simulations, where accurate force predictions are critical but often computationally expensive. In this work, we…

Machine Learning (ML) is profoundly reshaping the way researchers create, implement, and operate data-intensive software. Its adoption, however, introduces notable challenges for computing infrastructures, particularly when it comes to…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-10-30 Lucio Anderlini , Giulio Bianchini , Diego Ciangottini , Stefano Dal Pra , Diego Michelotto , Rosa Petrini , Daniele Spiga

Sea ice plays a critical role in the global climate system and maritime operations, making timely and accurate classification essential. However, traditional manual methods are time-consuming, costly, and have inherent biases. Automating…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Samira Alkaee Taleghan , Andrew P. Barrett , Walter N. Meier , Farnoush Banaei-Kashani

There is an increasing need in our society to achieve faster advances in Science to tackle urgent problems, such as climate changes, environmental hazards, sustainable energy systems, pandemics, among others. In certain domains like…

Artificial intelligence (AI) is currently spearheaded by machine learning (ML) methods such as deep learning which have accelerated progress on many tasks thought to be out of reach of AI. These recent ML methods are often compute hungry,…

Machine Learning · Computer Science 2025-03-25 Dustin Wright , Christian Igel , Gabrielle Samuel , Raghavendra Selvan

Artificial Intelligence (AI) workloads drive a rapid expansion of high-performance computing (HPC) infrastructures and increase their power and energy demands towards a critical level. AI benchmarks representing state-of-the art workloads…

Performance · Computer Science 2026-03-18 Martin Mayr , Sebastian Wind , Lukas Schröder , Georg Hager , Harald Köstler , Gerhard Wellein

Simulating atomic-scale processes, such as protein dynamics and catalytic reactions, is crucial for advancements in biology, chemistry, and materials science. Machine learning force fields (MLFFs) have emerged as powerful tools that achieve…

Chemical Physics · Physics 2024-12-30 Lars L. Schaaf , Ilyes Batatia , Christoph Brunken , Thomas D. Barrett , Jules Tilly

The literature has witnessed an emerging interest in AI agents for automated assessment of scientific papers. Existing benchmarks focus primarily on the computational aspect of this task, testing agents' ability to reproduce or replicate…

The convergence of artificial intelligence and materials science presents a transformative opportunity, but achieving true acceleration in discovery requires moving beyond task-isolated, fine-tuned models toward agentic systems that plan,…