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As a sensitive functional imaging technique, positron emission tomography (PET) plays a critical role in early disease diagnosis. However, obtaining a high-quality PET image requires injecting a sufficient dose (standard dose) of…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Caiwen Jiang , Mianxin Liu , Kaicong Sun , Dinggang Shen

To acquire high-quality positron emission tomography (PET) images while reducing the radiation tracer dose, numerous efforts have been devoted to reconstructing standard-dose PET (SPET) images from low-dose PET (LPET). However, the success…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Jiaqi Cui , Pinxian Zeng , Yuanyuan Xu , Xi Wu , Jiliu Zhou , Yan Wang

While Computed Tomography (CT) reconstruction from X-ray sinograms is necessary for clinical diagnosis, iodine radiation in the imaging process induces irreversible injury, thereby driving researchers to study sparse-view CT reconstruction,…

Image and Video Processing · Electrical Eng. & Systems 2021-11-29 Ce Wang , Kun Shang , Haimiao Zhang , Qian Li , Yuan Hui , S. Kevin Zhou

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation…

Computer Vision and Pattern Recognition · Computer Science 2017-12-13 Junshen Xu , Enhao Gong , John Pauly , Greg Zaharchuk

18F-fluorodeoxyglucose (18F-FDG) Positron Emission Tomography (PET) imaging usually needs a full-dose radioactive tracer to obtain satisfactory diagnostic results, which raises concerns about the potential health risks of radiation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-15 Yu Fu , Shunjie Dong , Yi Liao , Le Xue , Yuanfan Xu , Feng Li , Qianqian Yang , Tianbai Yu , Mei Tian , Cheng Zhuo

This paper studies 3D low-dose computed tomography (CT) imaging. Although various deep learning methods were developed in this context, typically they focus on 2D images and perform denoising due to low-dose and deblurring for…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Zhihao Chen , Chuang Niu , Qi Gao , Ge Wang , Hongming Shan

The adoption of Vision Transformers (ViTs) based architectures represents a significant advancement in 3D Medical Image (MI) segmentation, surpassing traditional Convolutional Neural Network (CNN) models by enhancing global contextual…

Computer Vision and Pattern Recognition · Computer Science 2024-04-25 Shehan Perera , Pouyan Navard , Alper Yilmaz

One of the major challenges in design and developing of PET, scanners are the presence of inactive areas between the detector blocks which degrade the image spatial resolution and leads to streaking artifacts especially when we employ…

Medical Physics · Physics 2019-06-19 Isaac Shiri , Peyman Sheikhzadeh , Mohammad Reza Ay

Cross-spectral image guided denoising has shown its great potential in recovering clean images with rich details, such as using the near-infrared image to guide the denoising process of the visible one. To obtain such image pairs, a…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Runmin Zhang , Zhu Yu , Zehua Sheng , Jiacheng Ying , Si-Yuan Cao , Shu-Jie Chen , Bailin Yang , Junwei Li , Hui-Liang Shen

Low-dose PET imaging is crucial for reducing patient radiation exposure but faces challenges like noise interference, reduced contrast, and difficulty in preserving physiological details. Existing methods often neglect both…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Mengxiao Geng , Ran Hong , Xiaoling Xu , Bingxuan Li , Qiegen Liu

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Positron Emission Tomography (PET) is a functional imaging modality that enables the visualization of biochemical and physiological processes across various tissues. Recently, deep learning (DL)-based methods have demonstrated significant…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Yiran Sun , Osama Mawlawi

Positron emission tomography (PET) offers powerful functional imaging but involves radiation exposure. Efforts to reduce this exposure by lowering the radiotracer dose or scan time can degrade image quality. While using magnetic resonance…

Computer Vision and Pattern Recognition · Computer Science 2026-02-13 Yingkai Zhang , Shuang Chen , Ye Tian , Yunyi Gao , Jianyong Jiang , Ying Fu

Low-Dose Computed Tomography (LDCT) technique, which reduces the radiation harm to human bodies, is now attracting increasing interest in the medical imaging field. As the image quality is degraded by low dose radiation, LDCT exams require…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Liutao Yang , Zhongnian Li , Rongjun Ge , Junyong Zhao , Haipeng Si , Daoqiang Zhang

Positron emission tomography(PET) image reconstruction is an ill-posed inverse problem and suffers from high level of noise due to limited counts received. Recently deep neural networks especially convolutional neural networks(CNN) have…

Image and Video Processing · Electrical Eng. & Systems 2022-10-25 Rui Hu , Huafeng Liu

Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…

Computer Vision and Pattern Recognition · Computer Science 2022-04-28 Ida Häggström , C. Ross Schmidtlein , Gabriele Campanella , Thomas J. Fuchs

Deep learning has significantly advanced PET image re-construction, achieving remarkable improvements in image quality through direct training on sinogram or image data. Traditional methods often utilize masks for inpainting tasks, but…

Computer Vision and Pattern Recognition · Computer Science 2025-03-12 Bin Huang , Binzhong He , Yanhan Chen , Zhili Liu , Xinyue Wang , Binxuan Li , Qiegen Liu

Positron Emission Tomography (PET) image reconstruction is inherently challenged by Poisson noise and physical degradation factors, which are further exacerbated in limited-angle acquisitions. While deep learning methods demonstrate…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Rüveyda Yilmaz , Yuli Wu , Johannes Stegmaier , Volkmar Schulz

Positron emission tomography (PET) is an advanced medical imaging technique that plays a crucial role in non-invasive clinical diagnosis. However, while reducing radiation exposure through low-dose PET scans is beneficial for patient…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Bin Huang , Xubiao Liu , Lei Fang , Qiegen Liu , Bingxuan Li
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