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Related papers: Motility induced phase separation of deformable ce…

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The motility-induced phase separation exhibited by active particles with repulsive interactions is well known. We show that the interaction softness of active particles destabilizes the highly ordered dense phase, leading to the formation…

Soft Condensed Matter · Physics 2022-09-21 Monika Sanoria , Raghunath Chelakkot , Amitabha Nandi

In active systems, whose constituents have non-equilibrium dynamics at local level, fluid-fluid phase separation is widely observed. Examples include the formation of membraneless organelles within cells; the clustering of self-propelled…

Soft Condensed Matter · Physics 2025-07-11 M. E. Cates , C. Nardini

Microphase separation of membrane components is thought to play an important role in many physiological processes, from cell signaling to endocytosis and cellular trafficking. Here, we study how variations in the membrane composition can be…

Subcellular Processes · Quantitative Biology 2015-05-20 Pierre Sens , Matthew S. Turner

Active particles, including swimming microorganisms, autophoretic colloids and droplets, are known to self-organize into ordered structures at fluid-solid boundaries. The entrainment of particles in the attractive parts of their spontaneous…

Soft Condensed Matter · Physics 2018-07-04 Shashi Thutupalli , Delphine Geyer , Rajesh Singh , Ronojoy Adhikari , Howard Stone

We study phase separation frustrated by the long-range Coulomb interaction in two dimensional electronic systems with emphasys in the case of a metallic and an insulating phase. We find that two-dimensional systems are more prone to…

Mesoscale and Nanoscale Physics · Physics 2009-11-11 C. Ortix , J. Lorenzana , C. Di Castro

Biological cells exhibit a hierarchical spatial organization, where various compartments harbor condensates that form by phase separation. Cells can control the emergence of these condensates by affecting compartment size, the amount of the…

Biological Physics · Physics 2025-04-03 Riccardo Rossetto , Gerrit Wellecke , David Zwicker

A hallmark of biological tissues, viewed as complex cellular materials, is the active generation of mechanical stresses by cellular processes, such as cell divisions. Each cellular event generates a force dipole that deforms the surrounding…

Engineered bacteria in which motility is reduced by local cell density generate periodic stripes of high and low density when spotted on agar plates. We study theoretically the origin and mechanism of this process in a kinetic model that…

Soft Condensed Matter · Physics 2015-06-04 Xiongfei Fu , Lei-Han Tang , Chenli Liu , Jian-Dong Huang , Terence Hwa , Peter Lenz

We propose a novel phase-field model to predict elastic microphase separation in polymer gels. To this end, we extend the Cahn-Hilliard free-energy functional to incorporate an elastic strain energy and a coupling term. These contributions…

Materials Science · Physics 2025-05-05 Hamza Oudich , Pietro Carrara , Laura De Lorenzis

Compartmentalization is ubiquitous in the broad cellular context, especially in the formation of membraneless organelles (MOs). Membraneless organelles (MOs) are phase-separated liquid compartments that provide spatiotemporal control of…

Biological Physics · Physics 2022-09-08 Jianhui Liu , Fariza Zhorabek , Ying Chau

Depth-averaged systems of equations describing the motion of fluid-sediment mixtures have been widely adopted by scientists in pursuit of models that can predict the paths of dangerous overland flows of debris. As models have become…

Fluid Dynamics · Physics 2026-04-07 Jake Langham , Xiannan Meng , Jamie P. Webb , Chris G. Johnson , J. M. N. T. Gray

We simulate active Brownian particles (ABPs) with soft-repulsive interactions subjected to a four-roll-mill flow. In the absence of flow, this system exhibits motility-induced phase separation (MIPS). To investigate the interplay between…

Soft Condensed Matter · Physics 2025-05-28 Soni D. Prajapati , Akshay Bhatnagar , Anupam Gupta

The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions. We…

Soft Condensed Matter · Physics 2020-05-28 Guanming Zhang , Romain Mueller , Amin Doostmohammadi , Julia M. Yeomans

Phase separation drives the formation of biomolecular condensates in cells, which comprise many components and sometimes possess multiple phases. The equilibrium physics of phase separation is well understood, but many components in…

Soft Condensed Matter · Physics 2025-08-14 Yicheng Qiang , Chengjie Luo , David Zwicker

Membrane shape fluctuations induce attractive interactions between rigid inclusions. Previous analytical studies showed that the fluctuation-induced pair interactions are rather small compared to thermal energies, but also that multi-body…

Soft Condensed Matter · Physics 2009-11-07 Thomas R Weikl

Studies of active matter, from molecular assemblies to animal groups, have revealed two broad classes of behavior: a tendency to align yields orientational order and collective motion, whereas particle repulsion leads to self-trapping and…

Soft Condensed Matter · Physics 2021-11-23 Jie Zhang , Ricard Alert , Jing Yan , Ned S. Wingreen , Steve Granick

A model of multicellular systems with several types of cells is developed from the phase field model. The model is presented as a set of partial differential equations of the field variables, each of which expresses the shape of one cell.…

Biological Physics · Physics 2015-05-30 Makiko Nonomura

Biological cells sense and respond to mechanical forces, but how such a mechanosensing proccess takes place in a nonlinear inhomogeneous fibrous matrix remains unknown. We show that cells in a fibrous matrix induce deformation fields that…

Biological Physics · Physics 2015-06-10 Jacob Notbohm , Ayelet Lesman , Phoebus Rosakis , David A. Tirrell , Guruswami Ravichandran

We study binary mixtures of small active and big passive athermal particles interacting via soft repulsive forces on a frictional substrate. Athermal self propelled particles are known to phase separate into a dense aggregate and a dilute…

Soft Condensed Matter · Physics 2018-07-05 Pritha Dolai , Aditi Simha , Shradha Mishra

Systems containing active components are intrinsically out of equilibrium, while binary mixtures reach their equilibrium configuration when complete phase separation is achieved. Active particles are found to stabilise non-equilibrium…

Soft Condensed Matter · Physics 2025-03-11 Javier Diaz , Ignacio Pagonabarraga