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We present a single-image numerical phase retrieval method for Zernike phase-contrast microscopy (ZPM) that addresses halo and shade-off artifacts, as well as the weak phase condition, without requiring hardware modifications. By employing…
Optical diffraction tomography (ODT) is a three-dimensional (3D) label-free imaging technique. The 3D refractive index distribution of a sample can be reconstructed from multiple two-dimensional optical field images via ODT. Herein, we…
This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…
The rise in virtual and mixed reality systems has prompted a resurgence of interest in two-dimensional and three-dimensional real-time computer generated holography. Phase randomisation is an integral part of holographic projection as it…
We present a novel approach to implement compressive sensing in laser scanning microscopes (LSM), specifically in image scanning microscopy (ISM), using a single-photon avalanche diode (SPAD) array detector. Our method addresses two…
We demonstrate two-step phase-shifting interferometry (holography) of complex laser modes generated by a spatial light modulator (SLM), in which the amplitude and phase of the signal are determined directly from measurements of…
Reflections often degrade the visual quality of images captured through transparent surfaces, and reflection removal methods suffers from the shortage of paired real-world samples.This paper proposes a hybrid approach that combines…
Computer-generated holograms (CGHs) are used in holographic three-dimensional (3D) displays and holographic projections. The quality of the reconstructed images using phase-only CGHs is degraded because the amplitude of the reconstructed…
Super Resolution (SR) plays a critical role in computer vision, particularly in medical imaging, where hardware and acquisition time constraints often result in low spatial and temporal resolution. While diffusion models have been applied…
Flexible fiber-optic endoscopes provide a minimally-invasive solution for imaging at depths beyond the reach of conventional microscopes. Current endoscopes require focusing and/or scanning mechanisms at the distal end, which limit…
We develop a novel algorithm for large-scale holographic reconstruction of 3D particle fields. Our method is based on a multiple-scattering beam propagation method (BPM) combined with sparse regularization that enables recovering dense 3D…
Medical head CT-scan imaging has been successfully combined with deep learning for medical diagnostics of head diseases and lesions[1]. State of the art classification models and algorithms for this task usually are based on 3d convolution…
Multimodal nonlinear endoscopes have been a topic of intense research over the past two decades, enabling sub-cellular and label-free imaging in areas not reachable with table-top microscopes. They are sophisticated systems that can be…
Label-free single-cell imaging offers a scalable, non-invasive alternative to fluorescence-based cytometry, yet inferring molecular phenotypes directly from bright-field morphology remains challenging. We present a unified Deep Learning…
High-dynamic-range (HDR) imaging is an essential technique for overcoming the dynamic range limits of image sensors. The classic method relies on multiple exposures, which slows capture time, resulting in motion artifacts when imaging…
Medical image segmentation has achieved remarkable advancements using deep neural networks (DNNs). However, DNNs often need big amounts of data and annotations for training, both of which can be difficult and costly to obtain. In this work,…
Binary amplitude spatial light modulators, such as digital micromirror devices (DMDs), are increasingly relevant for computer generated holography due to their high refresh rates, low cost, and due to the emergence of subwavelength pixel…
This work describes a novel approach to time-multiplexed holographic projection on binary phase devices. Unlike other time-multiplexed algorithms where each frame is the inverse transform of independently modified target images,…
Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer…
Laser Doppler holography (LDH) is an interferometric blood flow imaging technique based on full-field measurements of the Doppler spectrum. LDH has so far been demonstrated in the retina with ultrafast cameras, typically at 75 kHz. We show…