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Variational quantum algorithms (VQAs) have demonstrated considerable potential in solving NP-hard combinatorial problems in the contemporary near intermediate-scale quantum (NISQ) era. The quantum approximate optimisation algorithm (QAOA)…

Quantum Physics · Physics 2024-05-09 Boy Choy , David J. Wales

Quantum computers have now surpassed classical simulation limits, yet noise continues to limit their practical utility. As the field shifts from proof-of-principle demonstrations to early deployments, there is no standard method for…

Quantum Physics · Physics 2025-05-29 J. A. Montanez-Barrera , Kristel Michielsen , David E. Bernal Neira

Quantum computing offers new heuristics for combinatorial problems. With small- and intermediate-scale quantum devices becoming available, it is possible to implement and test these heuristics on small-size problems. A candidate for such…

Quantum Physics · Physics 2025-07-15 David Fitzek , Toheed Ghandriz , Leo Laine , Mats Granath , Anton Frisk Kockum

The Quantum Approximate Optimization Algorithm (QAOA) represents a significant opportunity for practical quantum computing applications, particularly in the era before error correction is fully realized. This algorithm is especially…

Quantum Physics · Physics 2024-10-08 Yiwen Liu , Qingyue Jiao , Yidong Zhou , Zhiding Liang , Yiyu Shi , Ke Wan , Shangjie Guo

Optimization problems are critical across various domains, yet existing quantum algorithms, despite their great potential, struggle with scalability and accuracy due to excessive reliance on entanglement. To address these limitations, we…

Quantum Physics · Physics 2025-03-04 Seongmin Kim , In-Saeng Suh

As power systems expand, solving the Unit Commitment Problem (UCP) becomes increasingly challenging due to the dimensional catastrophe, and traditional methods often struggle to balance computational efficiency and solution quality. To…

Systems and Control · Electrical Eng. & Systems 2025-03-27 Jingxian Zhou , Ziqing Zhu , Linghua Zhu , Siqi Bu

Traffic optimization on roads is a highly complex problem, with one important aspect being minimization of traffic congestion. By mapping to an Ising formulation of the traffic congestion problem, we benchmark solutions obtained from the…

The quantum approximate optimization algorithm (QAOA) is a method of approximately solving combinatorial optimization problems. While QAOA is developed to solve a broad class of combinatorial optimization problems, it is not clear which…

Quantum Physics · Physics 2020-08-13 James Ostrowski , Rebekah Herrman , Travis S. Humble , George Siopsis

Quantum optimization algorithms (QOAs) have the potential to fundamentally transform the application of optimization methods in decision making. For certain classes of optimization problems, it is widely believed that QOA enables…

Quantum Physics · Physics 2024-01-15 Florian Klug

Quantum Approximation Optimization Algorithm (QAOA) is a highly advocated variational algorithm for solving the combinatorial optimization problem. One critical feature in the quantum circuit of QAOA algorithm is that it consists of…

Quantum Physics · Physics 2022-07-21 Yuwei Jin , Jason Luo , Lucent Fong , Yanhao Chen , Ari B. Hayes , Chi Zhang , Fei Hua , Eddy Z. Zhang

The quantum alternating operator ansatz (QAOA) is a prominent example of variational quantum algorithms. We propose a generalized QAOA called CD-QAOA, which is inspired by the counterdiabatic driving procedure, designed for quantum…

Quantum Physics · Physics 2021-10-05 Jiahao Yao , Lin Lin , Marin Bukov

Variational quantum algorithms are the centerpiece of modern quantum programming. These algorithms involve training parameterized quantum circuits using a classical co-processor, an approach adapted partly from classical machine learning.…

Quantum Physics · Physics 2022-11-09 V. Akshay , H. Philathong , E. Campos , D. Rabinovich , I. Zacharov , Xiao-Ming Zhang , J. Biamonte

The Quantum Approximate Optimization Algorithm (QAOA) requires considered optimization problems to be translated into a compatible format. A popular transformation step in this pipeline involves the quadratization of higher-order binary…

Quantum Physics · Physics 2025-11-26 Damian Rovara , Lukas Burgholzer , Robert Wille

The Quantum Approximate Optimization Algorithm (QAOA) is suggested as a promising application on early quantum computers. Here, a quantum-inspired classical algorithm, the mean-field Approximate Optimization Algorithm (mean-field AOA), is…

Quantum Annealing (QA) and QAOA are promising quantum optimisation algorithms used for finding approximate solutions to combinatorial problems on near-term NISQ systems. Many NP-hard problems can be reformulated as Quadratic Unconstrained…

Quantum Physics · Physics 2025-10-06 Namasi G Sankar , Georgios Miliotis , Simon Caton

The quantum approximate optimization algorithm (QAOA) is a promising quantum-classical hybrid technique to solve combinatorial optimization problems in near-term gate-based noisy quantum devices. In QAOA, the objective is a function of the…

Quantum Physics · Physics 2019-07-24 Mahabubul Alam , Abdullah Ash-Saki , Swaroop Ghosh

Running quantum circuits on quantum computers does not always generate "clean" results, unlike on a simulator, as noise plays a significant role in any quantum device. To explore this, we experimented with the Quantum Approximate…

Quantum Physics · Physics 2025-10-09 Abyan Khabir Irfan , Chansu Yu

With the rapid advancement of quantum computing, Quantum Approximate Optimization Algorithm (QAOA) is considered as a promising candidate to demonstrate quantum supremacy, which exponentially solves a class of Quadratic Unconstrained Binary…

Quantum Physics · Physics 2023-10-11 Bo Yue , Shibei Xue , Yu Pan , Min Jiang , Daoyi Dong

Virtual screening, including molecular docking, plays an essential role in drug discovery. Many traditional and machine-learning based methods are available to fulfil the docking task. The traditional docking methods are normally…

Chemical Physics · Physics 2023-03-20 YuPeng Huang , Hong Zhang , Siyuan Jiang , Dajiong Yue , Xiaohan Lin , Jun Zhang , Yi Qin Gao

Demonstrating the practical utility of Noisy Intermediate-Scale Quantum (NISQ) hardware for recurrent tasks in Computer-Aided Drug Discovery is of paramount importance. We tackle this challenge by performing three-dimensional protein…

Quantum Physics · Physics 2025-12-12 Daniele Loco , Kisa Barkemeyer , Andre R. R. Carvalho , Jean-Philip Piquemal