English
Related papers

Related papers: Molecular docking via quantum approximate optimiza…

200 papers

Molecular docking is a critical process for drug discovery and challenging due to the complexity and size of biomolecular systems, where the optimal binding configuration of a drug to a target protein is determined. Hybrid classical-quantum…

Emerging Technologies · Computer Science 2025-03-07 Christos Papalitsas , Yanfei Guan , Shreyas Waghe , Athanasios Liakos , Ioannis Balatsos , Vassilios Pantazopoulos

The quantum approximate optimization algorithm (QAOA) has proved to be an effective classical-quantum algorithm serving multiple purposes, from solving combinatorial optimization problems to finding the ground state of many-body quantum…

Quantum Physics · Physics 2022-03-08 P. Chandarana , N. N. Hegade , K. Paul , F. Albarrán-Arriagada , E. Solano , A. del Campo , Xi Chen

Molecular docking (MD) is a crucial task in drug design, which predicts the position, orientation, and conformation of the ligand when bound to a target protein. It can be interpreted as a combinatorial optimization problem, where quantum…

Chemical Physics · Physics 2024-04-15 Yunting Li , Xiaopeng Cui , Zhaoping Xiong , Bowen Liu , Bi-Ying Wang , Runqiu Shu , Nan Qiao , Man-Hong Yung

Quantum Approximate Optimization Algorithm (QAOA) is one of the fundamental variational quantum algorithms, while a version of QAOA that includes counterdiabatic driving, termed Digitized Counterdiabatic QAOA (DC-QAOA), is generally…

Quantum Physics · Physics 2025-06-02 Jie Liu , Xin Wang

The bin packing problem, a classical NP-hard combinatorial optimization challenge, has emerged as a promising candidate for quantum computing applications. In this work, we address the one-dimensional bin packing problem (1dBPP) using a…

Quantum Physics · Physics 2026-04-28 Ruoqian Xu , Sebastián V. Romero , Jialiang Tang , Yue Ban , Xi Chen

Solving optimization tasks using variational quantum algorithms has emerged as a crucial application of the current noisy intermediate-scale quantum devices. However, these algorithms face several difficulties like finding suitable ansatz…

Quantum Physics · Physics 2022-06-22 Pranav Chandarana , Pablo S. Vieites , Narendra N. Hegade , Enrique Solano , Yue Ban , Xi Chen

Molecular docking is an important tool for structure-based drug design, accelerating the efficiency of drug development. Complex and dynamic binding processes between proteins and small molecules require searching and sampling over a wide…

Chemical Physics · Physics 2024-02-23 Runqiu Shu , Bowen Liu , Zhaoping Xiong , Xiaopeng Cui , Yunting Li , Wei Cui , Man-Hong Yung , Nan Qiao

Perfect Domination Problem (PDP), a canonical challenge in combinatorial optimization, finds critical applications in real-world systems such as error-correcting codes, wireless communication networks, and social networks. Decades of…

Quantum Physics · Physics 2025-09-18 Haoqian Pan , Changhong Lu , Yuqing Zheng , Chunxing Yan

The quantum approximate optimization algorithm (QAOA) is a near-term hybrid algorithm intended to solve combinatorial optimization problems, such as MaxCut. QAOA can be made to mimic an adiabatic schedule, and in the $p\to\infty$ limit the…

Quantum Physics · Physics 2022-02-02 Jonathan Wurtz , Peter J. Love

The Quantum Approximate Optimization Algorithm (QAOA) is an algorithmic framework for finding approximate solutions to combinatorial optimization problems, derived from an approximation to the Quantum Adiabatic Algorithm (QAA). In solving…

Quantum Physics · Physics 2020-02-05 Yue Ruan , Samuel Marsh , Xilin Xue , Xi Li , Zhihao Liu , Jingbo Wang

Developing quantum algorithms adaptive to specific constraints of near-term devices is an essential step towards practical quantum advantage. In a recent work [Phys. Rev. Lett. 131, 103601(2023)], we show cold atoms in an optical cavity can…

Quantum Physics · Physics 2024-06-12 Yuchen Luo , Xiaopeng Li , Jian Lin

We consider digitized-counterdiabatic quantum computing as an advanced paradigm to approach quantum advantage for industrial applications in the NISQ era. We apply this concept to investigate a discrete mean-variance portfolio optimization…

Quantum Physics · Physics 2022-12-29 N. N. Hegade , P. Chandarana , K. Paul , X. Chen , F. Albarrán-Arriagada , E. Solano

Protein folding -- the problem of predicting the spatial structure of a protein given its sequence of amino-acids -- has attracted considerable research effort in biochemistry in recent decades. In this work, we explore the potential of…

Quantum Physics · Physics 2022-04-06 Sami Boulebnane , Xavier Lucas , Agnes Meyder , Stanislaw Adaszewski , Ashley Montanaro

We introduce a counterdiabatic (CD) extension of the Quantum Approximate Optimization Algorithm (QAOA) for constrained portfolio optimization. By incorporating approximate adiabatic gauge potentials generated from nested commutators of the…

Quantum Physics · Physics 2026-05-11 Jose Falla , Ilya Safro

We propose a faster digital quantum algorithm for portfolio optimization using the digitized-counterdiabatic quantum optimization (DCQO) paradigm in the impulse regime, that is, where the counterdiabatic terms are dominant. Our approach…

Quantum approximate optimization algorithm (QAOA) has shown promise in solving combinatorial optimization problems by providing quantum speedup on near-term gate-based quantum computing systems. However, QAOA faces challenges for…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-03-24 Seongmin Kim , Vincent R. Pascuzzi , Zhihao Xu , Tengfei Luo , Eungkyu Lee , In-Saeng Suh

New computational strategies, such as molecular docking, are emerging to speed up the drug discovery process. This method predicts the activity of molecules at the binding site of proteins, helping to select the ones that exhibit desirable…

Quantum Physics · Physics 2024-02-13 Mathieu Garrigues , Victor Onofre , Noé Bosc-Haddad

Combinatorial optimization problems are ubiquitous and computationally hard to solve in general. Quantum approximate optimization algorithm (QAOA), one of the most representative quantum-classical hybrid algorithms, is designed to solve…

Quantum Physics · Physics 2024-03-12 Lixue Cheng , Yu-Qin Chen , Shi-Xin Zhang , Shengyu Zhang

The Quantum Approximate Optimization Algorithm (QAOA) is a well-known hybrid quantum-classical algorithm for combinatorial optimization problems. Improving QAOA involves enhancing its approximation ratio while addressing practical…

Quantum Physics · Physics 2025-02-07 Yukun Wang , ZeYang Li , Linchun Wan

Recently, Digitized-Counterdiabatic (CD) Quantum Approximate Optimization Algorithm (QAOA) has been proposed to make QAOA converge to the solution of an optimization problem in fewer steps, inspired by Trotterized counterdiabatic driving in…

Quantum Physics · Physics 2024-01-09 Mara Vizzuso , Gianluca Passarelli , Giovanni Cantele , Procolo Lucignano
‹ Prev 1 2 3 10 Next ›